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Enalkiren

  Cat. No.:  DC72378  
Chemical Structure
113082-98-7
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More than 5000 active chemicals with high quality for research!
Field of application
Enalkiren (A-64662) is a potent dipeptide renin inhibitor with an IC50 of 0.78 nM in a purified renal renin-angiotensinogen system (pH=6.0). Enalkiren suppresses renin activity, and also reduces systolic and diastolic blood pressure. Enalkiren can be used to research essential hypertension.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 113082-98-7
Chemical Name: Enalkiren
SMILES: O=C(N[C@H]([C@@H](O)[C@@H](O)CC(C)C)CC1CCCCC1)[C@@H](NC([C@@H](NC(CC(C)(N)C)=O)CC(C=C2)=CC=C2OC)=O)CC3=CN=CN3
Formula: C35H56N6O6
M.Wt: 656.86
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_36829_DC72378_113082-98-7
COA
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Cat. No. Product name Field of application
DC72378 Enalkiren Enalkiren (A-64662) is a potent dipeptide renin inhibitor with an IC50 of 0.78 nM in a purified renal renin-angiotensinogen system (pH=6.0). Enalkiren suppresses renin activity, and also reduces systolic and diastolic blood pressure. Enalkiren can be used to research essential hypertension.
DC72222 Remikiren Remikiren (Ro 42-5892) is an orally active and highly specific renin inhibitor. Remikiren specifically inhibits human reninand human plasma renin with IC50 values of 0.7 and 0.8 nM, respectively. Remikiren also reduces mean arterial blood pressure in sodium-depleted marmosets and squirrel monkeys. Remikiren can be used in study of hypertension.
DC72054 Aliskiren hydrochloride Aliskiren (CGP 60536; CGP60536B; SPP 100) hydrochloride is an orally active and selective renin inhibitor, with IC50 of 1.5 nM. Aliskiren hydrochloride can be used for the research of hypertension, cardiovascular diseases and cancer cachexia-.
DC71547 Aliskiren fumarate Aliskiren fumarate is an orally active, highly potent and selective renin inhibitor, with IC50 of 1.5 nM. Aliskiren fumarate can be used for the research of hypertension, cardiovascular diseases and cancer cachexia.
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