Cat. No. | Product name | CAS No. |
DC22316 |
NCC007
Featured
NCC007 is a novel CKIα and CKIδ dual inhibitor. NCC007 that showed stronger period effects (0.32 μM for 5 h period lengthening) in a cellbased circadian assay. |
|
DC21369 |
NCGC 00067819
Featured
NCGC 00067819 is a small molecule compound that potentiates CREB signaling with EC50 of 16 nM in the primary screen and 79 nM in the CHO CRE-β-lactamase confirmation assay. |
847163-23-9 |
DC10476 |
NCGC00244536
Featured
NCGC00244536 is a potent KDM4A inhibitor with an IC50 of 10 nM. |
2003260-55-5 |
DC10486 |
NCT-503
Featured
NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 2.5 µM. |
1916571-90-8 |
DC12128 |
NCT-505
Featured
NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM, and weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 (IC50s, >57, 22.8, 20.1, >57 μM). |
2231079-74-4 |
DC20004 |
NCT-506
Featured
NCT-506 is an orally bioavailable aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with an IC50 of 7 nM. |
2231098-99-8 |
DC10173 |
Firsocostat(ND-630,GS-0976)
Featured
ND-630 is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively. |
1434635-54-7 |
DC9810 |
ND-646
Featured
ND-646(ND646) is a small-molecule allosteric inhibitor of acetyl-CoA carboxylase (ACC). |
1434639-57-2 |
DC9347 |
N-desmethyl Enzalutamide
Featured
N-desmethyl Enzalutamide(N-desmethyl MDV3100) is a major metabolite of Enzalutamide, Enzalutamide(MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM. |
1242137-16-1 |
DC10438 |
N-Desmethylclozapine
Featured
N-Desmethylclozapine is a dengue virus inhibitor, and an agonist of δ-opioid receptor. |
6104-71-8 |
DC12348 |
NE 10790 (3-PEHPC)
Featured
NE 10790, a poor farnesyl pyrophosphate synthase inhibitor, is a phosphonocarboxylate analogue of the potent bisphosphonate risedronate and is a weak antiresorptive agent. |
152831-36-2 |
DC10455 |
NE-100
Featured
NE100 hydrochloride is a potent and selective σ1 receptor antagonist (Ki = 0.86 nM) that displays > 55-fold selectivity over σ2 receptors and > 6000-fold selectivity over D1, |
149409-57-4 |
DC10551 |
Necrostatin 2 racemate
Featured
Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM. |
852391-15-2 |
DC2084 |
Necrostatin-1
Featured
Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM. |
4311-88-0 |
DC9817 |
Necrosulfonamide (NSA)
Featured
Necrosulfonamide (NSA) is a very specific and potent necrosis inhibitor with an IC50 less than 0.2 uM. |
1360614-48-7 |
DC23292 |
Necrox-5 methanesulfonate
Featured
NecroX-5 is a novel necroptosis inhibitor that reduces mitochondrial oxidative stress, prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter. |
1383718-29-3 |
DC21375 |
NecroX-2
Featured
NecroX-2 is a small molecule necrosis modulator and potent antioxidant molecule, which can be bound to some types of radicals and especially NAPQI. |
1120333-38-1 |
DCAPI1393 |
Nedaplatin (Aqupla)
Featured
Nedaplatin (Aqupla) is a derivative of cisplatin for inhibition of tumor colony forming units with IC50 of 28.5 μg/mL. |
95734-82-0 |
DC20473 |
NEDD8 inhibitor M22
Featured
NEDD8 inhibitor M22 is a novel, potent, selective reversible NEDD8 activating enzyme (NAE) inhibitor. |
864420-54-2 |
DC9569 |
Nefazodone (hydrochloride)
Featured
Nefazodone hydrochloride is an antidepressant drug. |
82752-99-6 |
DC8194 |
PP3
Featured
Negative control for the Src kinase inhibitor PP2. |
5334-30-5 |
DC8290 |
(S)-PFI-2 HCl
Featured
Negative control of (R)-PFI 2 hydrochloride. Exhibits 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer. |
1627607-88-8 |