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Cat. No. Product name CAS No.
DC22316 NCC007 Featured

NCC007 is a novel CKIα and CKIδ dual inhibitor. NCC007 that showed stronger period effects (0.32 μM for 5 h period lengthening) in a cellbased circadian assay.

DC21369 NCGC 00067819 Featured

NCGC 00067819 is a small molecule compound that potentiates CREB signaling with EC50 of 16 nM in the primary screen and 79 nM in the CHO CRE-β-lactamase confirmation assay.

847163-23-9
DC10476 NCGC00244536 Featured

NCGC00244536 is a potent KDM4A inhibitor with an IC50 of 10 nM.

2003260-55-5
DC10486 NCT-503 Featured

NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 2.5 µM.

1916571-90-8
DC12128 NCT-505 Featured

NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM, and weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 (IC50s, >57, 22.8, 20.1, >57 μM).

2231079-74-4
DC20004 NCT-506 Featured

NCT-506 is an orally bioavailable aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with an IC50 of 7 nM.

2231098-99-8
DC10173 Firsocostat(ND-630,GS-0976) Featured

ND-630 is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively.

1434635-54-7
DC9810 ND-646 Featured

ND-646(ND646) is a small-molecule allosteric inhibitor of acetyl-CoA carboxylase (ACC).

1434639-57-2
DC9347 N-desmethyl Enzalutamide Featured

N-desmethyl Enzalutamide(N-desmethyl MDV3100) is a major metabolite of Enzalutamide, Enzalutamide(MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM.

1242137-16-1
DC10438 N-Desmethylclozapine Featured

N-Desmethylclozapine is a dengue virus inhibitor, and an agonist of δ-opioid receptor.

6104-71-8
DC12348 NE 10790 (3-PEHPC) Featured

NE 10790, a poor farnesyl pyrophosphate synthase inhibitor, is a phosphonocarboxylate analogue of the potent bisphosphonate risedronate and is a weak antiresorptive agent.

152831-36-2
DC10455 NE-100 Featured

NE100 hydrochloride is a potent and selective σ1 receptor antagonist (Ki = 0.86 nM) that displays > 55-fold selectivity over σ2 receptors and > 6000-fold selectivity over D1,

149409-57-4
DC10551 Necrostatin 2 racemate Featured

Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.

852391-15-2
DC2084 Necrostatin-1 Featured

Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.

4311-88-0
DC9817 Necrosulfonamide (NSA) Featured

Necrosulfonamide (NSA) is a very specific and potent necrosis inhibitor with an IC50 less than 0.2 uM.

1360614-48-7
DC23292 Necrox-5 methanesulfonate Featured

NecroX-5 is a novel necroptosis inhibitor that reduces mitochondrial oxidative stress, prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter.

1383718-29-3
DC21375 NecroX-2 Featured

NecroX-2 is a small molecule necrosis modulator and potent antioxidant molecule, which can be bound to some types of radicals and especially NAPQI.

1120333-38-1
DCAPI1393 Nedaplatin (Aqupla) Featured

Nedaplatin (Aqupla) is a derivative of cisplatin for inhibition of tumor colony forming units with IC50 of 28.5 μg/mL.

95734-82-0
DC20473 NEDD8 inhibitor M22 Featured

NEDD8 inhibitor M22 is a novel, potent, selective reversible NEDD8 activating enzyme (NAE) inhibitor.

864420-54-2
DC9569 Nefazodone (hydrochloride) Featured

Nefazodone hydrochloride is an antidepressant drug.

82752-99-6
DC8194 PP3 Featured

Negative control for the Src kinase inhibitor PP2.

5334-30-5
DC8290 (S)-PFI-2 HCl Featured

Negative control of (R)-PFI 2 hydrochloride. Exhibits 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer.

1627607-88-8
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