Cat. No. | Product name | CAS No. |
DC23617 |
NAB-14
Featured
NAB-14 is a potent, selective negative allosteric modulator of GluN2C/2D-containing NMDA receptors with IC50 of 580 nM, >800-fold selective over GluN2A/GluN2 receptors; inhibits triheteromeric (GluN1/GluN2A/GluN2C) NMDARs with modestly reduced potency and efficacy compared to diheteromeric (GluN1/GluN2C/GluN2C) receptors; inhibits GluN2D-mediated synaptic currents in rat subthalamic neurons and mouse hippocampal interneurons, but has no effect on synaptic transmission in hippocampal pyramidal neurons. |
1237541-73-9 |
DC21358 |
N-acetyl lysyltyrosylcysteine amide
Featured
N-Acetyl lysyltyrosylcysteine amide is a potent, reversible, specific, and non-toxic tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide effectively inhibits MPO generation of toxic oxidants in vivo. N-Acetyl lysyltyrosylcysteine amide reduces neuronal damage and preserves brain tissue and neurological function in the stroked brain. N-Acetyl lysyltyrosylcysteine amide inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL oxidation. |
1287585-40-3 |
DC23924 |
N-Acetyl-Calicheamicin
Featured
N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic. |
108212-76-6 |
DC21444 |
Nacubactam
Featured
Nacubactam (OP 0595, RG 6080, RO 7079901) is a diazabicyclooctane that inhibits class A and C β-lactamases with IC50 of <1 uM, also acts as a PBP2-active antibacterial. |
2007923-17-1 |
DC9619 |
Nafamostat (mesylate)
Featured
Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant,showed highly potent activity against COVID-19(SARS-COV-2). |
82956-11-4 |
DC23132 |
Nalfurafine hydrochloride
Featured
Nalfurafine (TRK-820, TRK820) is potent, selective agonist of kappa-opioid receptor with Ki of 3.5 nM, 15-fold less potent for μOR and little affinity for δOR (Ki=53 and 1,200 nM, respectively). |
152658-17-8 |
DC23102 |
Nalfurafine
Featured
Nalfurafine (TRK-820, TRK820) is potent, selective agonist of kappa-opioid receptor with Ki of 3.5 nM, 15-fold less potent for μOR and little affinity for δOR (Ki=53 and 1,200 nM, respectively). |
152657-84-6 |
DC20016 |
Naloxegol
Featured
Naloxegol is a CYP3A4 enzyme inhibitor, is a peripherally-selective opioid antagonist, for the treatment of opioid-induced constipation. |
854601-70-0 |
DC8492 |
Naloxegol Oxalate(NKTR-118)
Featured
Naloxegol is the first oral peripherally acting mu opioid receptor antagonists for opioid-induced constipation. |
1354744-91-4 |
DC8407 |
Naloxone HCl Dihydrate
Featured
Naloxone HCl Dihydrate is an opioid inverse agonist drug used to counter the effects of opiate overdose. |
51481-60-8 |
DC10266 |
Nandrolone decanoate
Featured
Nandrolone Decanoate is a mild form of an anabolic steroid. |
360-70-3 |
DC8474 |
Napabucasin (BBI608)
Featured
Napabucasin (BBI608) is an orally-administered small molecule which can block cancer stem cell (CSC) self-renewal and induces cell death in CSCs as well as non-stem cancer cells. |
83280-65-3 |
DC23157 |
Naspm trihydrochloride
Featured
Naspm is a selective antagonist of Ca2+-permeable AMPA receptors, blocks GluR2-lacking AMPARs, suppresses current responses induced by kainate in type II neurons with IC50 of 0.33 uM. |
1049731-36-3 |
DC9341 |
Naspm
Featured
Naspm(1-Naphthylacetyl spermine) is a potent and selective Ca2+ permeable AMPA receptor(Ca-perm AMPAR) blocker. IC50 value: Target: CP-AMPAR blocker Naspm is a selective blocker of Ca(2+)-permeable GluA2-lacking AMPA receptors, reduced MNNG-induced CA1 |
122306-11-0 |
DCAPI1056 |
Nattokinase
Featured
Nattokinase, Natto fermentation is a potent fibrinolytic enzyme. Nattokinase can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Nattokinase can be used for the research of cardiovascular diseases. |
133876-92-3 |
DC26021 |
6,8(2H,7H)-Isoquinolinedione,7-(acetyloxy)-5-chloro-3-(3,5-dimethyl-1,3-heptadienyl)-7-methyl- (9CI)
Featured
Natural product derived from fungal source. |
34695-81-3 |
DC11971 |
NAV-2729(Grassofermata)
Featured
NAV 2729 (NAV2729) is a chemical potentiator for mRNA-LNPs, increasing the delivery efficiencies of mRNA-LNPs in vitro and in vivo. NAV 2729 (NAV2729) is a novel, direct and selective small molecule inhibitor of small GTPase ARF6 with IC50 of 1.5 uM in nucleotide exchange assays. |
419547-11-8 |
DC20472 |
Naxillin
Featured
Naxillin is the first non-auxin-like molecule that promotes root branching, activates a subset of auxin-induced transcripts, including AUX/IAA, SAUR and PIN families; induces auxin response in the basal meristem; represents a valuable tool to further decipher the molecular networks involved in lateral root branching. |
301176-96-5 |
DC9790 |
Nazartinib(EGF816)
Featured
Nazartinib(EGF816) is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC. |
1508250-71-2 |
DC9476 |
NBD-556
Featured
NBD-556 is small molecule mimetic of CD4, NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. |
333353-44-9 |
DC11406 |
NBQX
Featured
NBQX is a potent aminomethylphosphonic acid receptor (AMPAR) antagonist with an IC50 of 0.7 ± 0.1 μM. |
118876-58-7 |
DC9770 |
NCB-0846
Featured
NCB-0846 is a novel,first-in-class,orally TNIK inhibitor with an IC50 value of 21 nM,that have shown strong anti-tumor efficacy against several cancer models. |
1792999-26-8 |