Cat. No. | Product name | CAS No. |
DC10843 |
CGP 52432
Featured
CGP 52432 is a potent, selective GABAB receptor antagonist (IC50 = 85 nM). |
139667-74-6 |
DC7381 |
CGP-57380
Featured
CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 (IC50 = 2.2 μM) with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases. |
522629-08-9 |
DC10722 |
CGP-71683A
Featured
CGP 71683A is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity. |
192322-50-2 |
DC23919 |
CGP-42112
Featured
CGP-42112 (CGP42112A) is a highly potent, selective Angiotensin-II subtype 2 receptor(AT2 receptor) agonist with Ki of 0.24 nM. |
127060-75-7 |
DC8471 |
CGS 21680 hydrochloride
Featured
CGS 21680 hydrochloride is an A2A adenosine receptor agonist (Ki = 27 nM). |
124431-80-7 |
DC7939 |
CH-223191
Featured
CH-223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor. |
301326-22-7 |
DC7102 |
CH5132799
Featured
CH5132799 selectively inhibits class I PI3Ks, such as PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ with IC50 values of 0.014, 0.12, 0.50, and 0.36 uM, respectively; shows less inhibition of class II PI3Ks, class III PI3ks, and mTOR. |
1007207-67-1 |
DC8418 |
CH5183284 (Debio-1347)
Featured
CH5183284 is a selective and orally available FGFR inhibitor with IC50 of 9.3 nM, 7.6 nM, 22 nM, and 290 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Phase 1. |
1265229-25-1 |
DC7383 |
CH5424802(Alectinib)
Featured
CH5424802(AF 802; Alectinib) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. |
1256580-46-7 |
DC8728 |
CH5424802(Alectinib HCl)
Featured
CH5424802(AF 802; Alectinib) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. |
1256589-74-8 |
DC22054 |
CH5447240
Featured
CH5447240 is a novel potent, selective, orally active hPTHR1 agonist with EC20 of 3.0 nM and EC50 of 12 nM. |
1253919-92-4 |
DC12415 |
CH7057288
Featured
CH7057288 (CH-7057288) is a novel potent and selective pan-TRK inhibitor with IC50 of 1.1/7.8/5.1 nM for TRKA/TRKB/TRKC, respectively. |
2095616-82-1 |
DC23101 |
Chelerythrine chloride
Featured
Chelerythrine is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase, or calcium/calmodulin-dependent protein kinase. |
3895-92-9 |
DC20266 |
Chelerythrine
Featured
Chelerythrine is a well-known protein kinase C inhibitor, can inhibit telomerase activity, it also can block the human P2X 7 receptor. |
34316-15-9 |
DC20100 |
Chelidonic acid
Featured
Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blo |
99-32-1 |
DC21405 |
Chetomin
Featured
Chetomin (NSC 289491) is a natural product isolated from Chaetomium species which shows antibacterial and antifungal properties, disrupts the interaction of HIF-1α/p300 at low nanomolar concentrations, strongly increases retinal pigment epithelial cells d |
1403-36-7 |
DC7978 |
Tucidinostat(Chidamide)
Featured
Chidamide is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM); no inhibition on HDAC4/5/7/9/6(IC50>30 uM). |
743420-02-2 |
DC9292 |
CHIR-090
Featured
CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. |
728865-23-4 |
DC7384 |
CHIR-98014
Featured
CHIR-98014 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2. |
252935-94-7 |
DC9703 |
CHIR-99021 HCl
Featured
CHIR-99021 HCl is a glycogen synthase kinase 3 beta inhibitor that has antiproliferative activity in vitro and in vivo. |
1797989-42-4 |
DC1023 |
CHIR-99021 (CT99021)
Featured
CHIR-99021 is a glycogen synthase kinase 3 beta inhibitor that has antiproliferative activity in vitro and in vivo. |
252917-06-9 |
DC9082 |
Chlorpromazine HCl
Featured
Chlorpromazine Hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug. |
69-09-0 |