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Cat. No. Product name CAS No.
DC10670 CNQX Featured

CNQX is a potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.

115066-14-3
DC23180 CNV1014802(Raxatrigine) Featured

CNV1014802 (GSK-1014802, Raxatrigine, Vixotrigine, BIIB074) is a potent, selective Nav1.7 sodium channel blocker, shows analgesic effects and potential in the treatment of cognitive symptoms of schizophrenia in vivo.

934240-30-9
DC8095 Raxatrigine hydrochloride Featured

CNV1014802(GSK-1014802) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor.

934240-31-0
DC7105 CNX-2006 Featured

CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.

1375465-09-0
DC7161 CNX-774 Featured

CNX-774 is a potent, selective, and orally available small molecule inhibitor of Btk (IC50< 1 nM) that forms a ligand-directed covalent bond with Cys-481, a non-conserved amino acid within the active site of the enzyme.

1202759-32-7
DC8651 CO-1686 hydrobromide Featured

CO-1686 hydrobromide is a novel, irreversible and orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M (IC50=21 nM).

1446700-26-0
DC7106 Rociletinib (CO-1686) Featured

CO-1686 is a novel, irreversible and orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M(IC50=21 nM).

1374640-70-6
DC2046 Cobicistat (GS-9350) Featured

Cobicistat (GS-9350) is a potent and selective inhibitor of CYP3A with IC50 of 30-285 nM.

1004316-88-4
DC8863 Coelenterazine Featured

Coelenterazine is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques.

55779-48-1
DC10336 Coenzyme Q9 Featured

Coenzyme Q9, a nine isoprenyl group-containing member of the ubiquinone family, is a normal constituent of human plasma.

303-97-9
DC11955 Takeda compound 101 Featured

Compound 101 (GRK2 inhibitor 101, Takeda compound 101, Cmpd101) is a novel membrane-permeable, small-molecule inhibitor of GRK2 and GRK3.

865608-11-3
DC2085 Compound 401 Featured

Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over FRAP (mTOR) (IC50 = 5.3 µM).

168425-64-7
DC8340 myo-Inositol,1,2-anhydro- Featured

Conduritol B Epoxide (CBE) is a specific covalent inhibitor of β-glucosidase which results in the accumulation of glucocerebroside.

6090-95-5
DCAPI1091 Conivaptan hydrochloride Featured

Conivaptan(YM 087) is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist) with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively.

168626-94-6
DC8477 VER-49009 Featured

Consistent with inhibition of Hsp90, VER-49009 induces the expression of Hsp27 and Hsp72 while reducing the client proteins C-RAF, B-RAF, survivin, and PRMT5, causing cell cycle arrest and apoptosis.

558640-51-0
DC10776 Cordycepin Featured

Cordycepin is an adenosine analogue, which is readily phosphorylated to its mono-, di-, and triphosphate intracellularly. It has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities.

73-03-0
DC12098 Corin Featured

Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1.

1808113-09-8
DC11104 Tildacerfont Featured

corticotropin releasing factor (CRF) antagonist.

1014983-00-6
DC22488 Corticotropin-releasing factor (human) Featured

Corticotropin-releasing hormone (CRH) is a peptide hormone involved in the stress response..

86784-80-7
DC23908 Cortisone Featured

Cortisone is a pregnane (21-carbon) steroid hormone, one of the main hormones released by the adrenal gland in response to stress.

53-06-5
DC10686 Cosan-528 Featured

Cosan-528 is a bioactive chemical.

96686-51-0
DC10657 COTI-2 Featured

COTI-2 is a small molecule candidate anti-cancer drug which can convert mutant p53 to wild-type conformation.

1039455-84-9
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