| DC22517 |
Exendin-4 acetate
Featured
|
Exenatide acetate (Exendin-4 acetate) is the acetate of Exenatide, which is highly potent, long-acting glucagon-like peptide-1 receptor (GLP-1) agonist with IC50 of 3.22 nM.. |
|
| DC9532 |
ADH-1 trifluoroacetate
Featured
|
Exherin (ADH-1) trifluoroacetate is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities; selectively and competitively binds to and blocks N-cadherin.
|
|
| DC10905 |
Exo1
Featured
|
Exo1 is a cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 µM). |
|
| DC7204 |
Ezatiostat(TER199; TLK199)
Featured
|
Ezatiostat(TER199; TLK199) is a glutathione analog inhibitor of glutathione S-transferase (GST) P1-1. |
|
| DCAPI1084 |
Ezetimibe (Zetia)
Featured
|
Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. |
|
| DC10679 |
EZM2302
Featured
|
EZM2302 (GSK3359088) is the first potent and selective inhibitor of CARM1 enzymatic activity that exhibits anti-proliferative effects both in vitro and in vivo,in biochemical assays (IC50=6nM) with broad selectivity against histone methyltransferases. |
|
| DC9821 |
Ezutromid
Featured
|
Ezutromid is a novel Small utrophin's translation modulator with EC50 of 0.4 uM . |
|
| DC10838 |
F1063-0967
Featured
|
F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM. |
|
| DC11329 |
Fadrozole (hydrochloride)
Featured
|
Fadrozole is a non-steroidal aromatase inhibitor (IC50s = 5 and 1.4 nM for human placental and rat ovarian microsomal aromatase, respectively). |
|
| DC10910 |
Fantofarone
Featured
|
Fantofarone is a calcium channel blocker. |
|
| DC10382 |
Farampator
Featured
|
Farampator (CX-691;Org24448) is an AMPA receptor positive modulator. |
|
| DC24118 |
C75
Featured
|
C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM). |
|
| DC11864 |
Fascaplysin (chloride)|CDK4 inhibitor
Featured
|
Fascaplysin is a potent, selective ATP-competitive CDK4 inhibitor (IC50 = 350 nM). |
|
| DC20381 |
Fasentin
Featured
|
Fasentin is a novel inhibitor of glucose uptake (GLUT) that sensitizes cancer cells to FAS-induced cell death, preferentially inhibits GLUT4 (IC50=68 uM) over GLUT1. |
|
| DC7413 |
Fasudil-HA
Featured
|
Fasudil Hcl(HA-1077; AT-877) is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively. |
|
| DC10213 |
Fatostatin
Featured
|
Fatostatin ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. |
|
| DC23119 |
FB23-2(FTO Demethylase inhibitor FB23-2)
Featured
|
FB23-2 is a potent, selective inhibitor of the mRNA N 6-methyladenosine (m 6A) demethylase FTO, directly bind to FTO, inhibits FTO demethylation of m6 A in RNA in vitro with IC50 of 2.6 uM. |
|
| DC23507 |
FC131
Featured
|
FC131 (cyclo(-D-Tyr-Arg-Arg-Nal-Gly-)) is a selective, cyclopentapeptide CXCR4 antagonist with IC50 of 126 nM, exhibits anti-HIV activity in assays using NL4-3 and IIIB strains with EC50 of 21 nM.. |
|
| DC9753 |
FCCP
Featured
|
FCCP is a very potent uncoupler of oxidative phosphorylation in mitochondria,that disrupts ATP synthesis by transporting protons across cell membranes. |
|
| DC26037 |
FDL-169
Featured
|
FDL-169 is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector being developed by Flatley Discovery Lab for treating cystic fibrosis (CF) patients who carry the F508del mutation |
|
| DCAPI1591 |
FEBUXOSTAT
Featured
|
FEBUXOSTAT is an inhibitor xanthine oxidase and xanthine dehydrogenase |
|
| DC5099 |
Felbamate
Featured
|
Felbamate (Felbatol) is an anticonvulsant drug used in the treatment of epilepsy. |
|
| DC9424 |
Fenoldopam (mesylate)
Featured
|
Fenoldopam(SKF 82526) mesylate is a drug and synthetic benzazepine derivative which acts as a selective D1 receptor partial agonist.
|
|
| DC8684 |
Fenoxaprop-P-ethyl
Featured
|
Fenoxaprop-P-ethyl is a post-emergent phenoxy herbicide of the aryloxyphenoxy propionate group. |
|
| DC7714 |
Fenretinide (4-HPR)
Featured
|
Fenretinide (4-HPR) is a synthetic retinoid deriverative. 4-HBR is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death. |
|
| DC10742 |
Ferrostatin-1 (Fer-1)
Featured
|
Ferrostatin-1 is a selective inhibitor of erastin induced ferroptosis with EC50 value of 60 nM. |
|
| DC20102 |
Ferulic acid methyl ester
Featured
|
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties. Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical s |
|
| DC8912 |
Fesoterodine fumarate
Featured
|
Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist. |
|
| DC11278 |
Fevipiprant
Featured
|
Fevipiprant(QAW039) is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change. |
|
| DC8069 |
Fexaramate
Featured
|
Fexaramate is a potent, selective farnesoid X receptor agonist. |
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