ALX-1393|ALX 1393;ALX1393

Cas No.:	949164-09-4
Chemical Name:	(2S)-2-amino-3-[(3-fluorophenyl)-(2-phenylmethoxyphenyl)methoxy]propanoic acid
Synonyms:	ALX 1393;ALX1393
SMILES:	C(O)(=O)[C@H](N)COC(C1=CC=CC(F)=C1)C1=CC=CC=C1OCC1=CC=CC=C1
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

ALX-1393 (ALX 1393, ALX1393) is a potent, specific GlyT2 inhibitor with Ki of <1 uM; ameliorates dynamic and static mechanical allodynia in mice with herpetic or postherpetic pain, displays antinociceptive effects on in vivo.

Cat. No.	Product name	Field of application
DC11035	GlyT1 inhibitor 46	GlyT1 inhibitor 46 is a novel potent, selective, orally available inhibitor of glycine transporter-1 (GlyT1) with IC50 of 38 and 21 nM for rat and human GlyT1, respectively.
DC11840	ALX-1393	ALX-1393 (ALX 1393, ALX1393) is a potent, specific GlyT2 inhibitor with Ki of <1 uM.
DC11839	Org 25543	A potent, highly selective glycine transporter 1 (GlyT2) inhibitor with IC50 of 16 nM with negligible affinity for GlyT1..