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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC4193 Decitabine Featured Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively.
DC12144 Decursin ((+)-Decursin) Featured Decursin is an anticancer agent, with potential anti-inflammatory activity.
DC7695 Defactinib (VS-6063, PF-04554878) Featured Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel.
DC10100 Defactinib hydrochloride Featured Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel.
DC10822 Defensamide(MHP) Featured Defensamide, also known as MHP and methyl caprooyl tyrosinate, is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.
DCAPI1107 Deferasirox (Exjade) Featured Deferasirox (Exjade)
DC7399 Deferitrin Featured Deferitrin (GT-56-252) is the first drug in a class of desferrithiocin-derived hexadentate iron chelators.
DC11332 Degarelix (acetate) Featured Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist (IC50 = 3 nM in HEK293 cells expressing the human receptor).
DC9337 Deguelin Featured Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to have an anti-tumor effect on several cancers; decrease levels of phosphorylated Akt.
DC5201 Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone(DHEA) is a 19-carbon endogenous natural steroid hormone.
DC23727 Dehydromutactin Dehydromutactin is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 40 nM.
DC12073 Dehydronitrosonisoldipine Dehydronitrosonisoldipine is a calcium channel antagonist.
DC8866 DEL-22379 Featured DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ∼0.5 μM.
DC10458 Delafloxacin(ABT-492) Featured Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent.
DC20116 Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) Featured Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and
DC7764 Delamanid (OPC-67683) Featured Delamanid (OPC-67683) is an experimental drug for the treatment of multi-drug-resistant tuberculosis.
DC8481 Delanzomib(CEP-18770) Featured Delanzomib(CEP-18770) is a novel orally-active inhibitor of the chymotrypsin-like activity of the proteasome that down-modulates the nuclear factor-kappaB (NF-kappaB) activity.
DC11352 Delavirdine (mesylate) Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that selectively inhibits HIV-1 reverse transcriptase over DNA polymerase α and δ in vitro (IC50s = 0.26, 440, and >550 μM, respectively).
DC8897 Delavirdine Delavirdine(U 90152) is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI).
DC20772 Deleobuvir Deleobuvir (BI-207127, BI207127) is a potent, selective HCV NS5B polymerase inhibitor with IC50 of 50 nM against GT-1 HCV polymerase activity.
DC11890 Delgocitinib Featured Delgocitinib (JTE-052, LEO 124249) is a potent, selective, orally active, pan-JAK inhibitor with IC50 of 2.8, 2.6, 13 and 58 nM for JAK1,2,3 and Tyk2, respectively.
DC10612 Delpazolid (LCB01-0371) Featured Delpazolid (LCB01-0371) is a new oxazolidinone with cyclic amidrazone.
DC8205 Deltarasin Featured Deltarasin is a novel and small molecule inhibitor which can inhibit the KRAS-PDEδ interaction(Kd= 41 nM. binding to PDEδ) and impairs oncogenic KRAS signalling.
DC20948 Deltasonamide 2 Deltasonamide 2 (Deltasonamide-2) is a novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM.
DC26004 delta-Valerobetaine (hydrobromide) Featured Delta-Valerobetaine (hydrobromide) is a precursor of trimethylamine N-oxide (TMAO).
DC20949 Deltazinone 1 Deltazinone 1 (Deltazinone1) is a novel highly selective PDEδ inhibitor that inhibits PDEδ/Ras interaction with Kd of 8±4 nM.
DC10850 Dencichine Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity.
DC7199 Denibulin (MN-029) Denibulin (MN-029) is a novel vascular-disrupting agent that reversibly inhibits microtubule assembly, resulting in disruption of the cytoskeleton of tumor vascular endothelial cells.
DC8712 Deoxycorticosterone acetate Featured Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.
DC10308 Deoxycytidine triphosphate Deoxycytidine triphosphate (dCTP), a nucleoside triphosphate, is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

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