DC4193 |
Decitabine
Featured
|
Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively. |
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DC12144 |
Decursin ((+)-Decursin)
Featured
|
Decursin is an anticancer agent, with potential anti-inflammatory activity. |
|
DC7695 |
Defactinib (VS-6063, PF-04554878)
Featured
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Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel. |
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DC10100 |
Defactinib hydrochloride
Featured
|
Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel. |
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DC10822 |
Defensamide(MHP)
Featured
|
Defensamide, also known as MHP and methyl caprooyl tyrosinate, is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC. |
|
DCAPI1107 |
Deferasirox (Exjade)
Featured
|
Deferasirox (Exjade) |
|
DC7399 |
Deferitrin
Featured
|
Deferitrin (GT-56-252) is the first drug in a class of desferrithiocin-derived hexadentate iron chelators. |
|
DC11332 |
Degarelix (acetate)
Featured
|
Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist (IC50 = 3 nM in HEK293 cells expressing the human receptor). |
|
DC9337 |
Deguelin
Featured
|
Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to have an anti-tumor effect on several cancers; decrease levels of phosphorylated Akt.
|
|
DC5201 |
Dehydroepiandrosterone (DHEA) |
Dehydroepiandrosterone(DHEA) is a 19-carbon endogenous natural steroid hormone. |
|
DC23727 |
Dehydromutactin |
Dehydromutactin is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 40 nM. |
|
DC12073 |
Dehydronitrosonisoldipine |
Dehydronitrosonisoldipine is a calcium channel antagonist. |
|
DC8866 |
DEL-22379
Featured
|
DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ∼0.5 μM. |
|
DC10458 |
Delafloxacin(ABT-492)
Featured
|
Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. |
|
DC20116 |
Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine)
Featured
|
Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and |
|
DC7764 |
Delamanid (OPC-67683)
Featured
|
Delamanid (OPC-67683) is an experimental drug for the treatment of multi-drug-resistant tuberculosis. |
|
DC8481 |
Delanzomib(CEP-18770)
Featured
|
Delanzomib(CEP-18770) is a novel orally-active inhibitor of the chymotrypsin-like activity of the proteasome that down-modulates the nuclear factor-kappaB (NF-kappaB) activity. |
|
DC11352 |
Delavirdine (mesylate) |
Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that selectively inhibits HIV-1 reverse transcriptase over DNA polymerase α and δ in vitro (IC50s = 0.26, 440, and >550 μM, respectively). |
|
DC8897 |
Delavirdine |
Delavirdine(U 90152) is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI). |
|
DC20772 |
Deleobuvir |
Deleobuvir (BI-207127, BI207127) is a potent, selective HCV NS5B polymerase inhibitor with IC50 of 50 nM against GT-1 HCV polymerase activity. |
|
DC11890 |
Delgocitinib
Featured
|
Delgocitinib (JTE-052, LEO 124249) is a potent, selective, orally active, pan-JAK inhibitor with IC50 of 2.8, 2.6, 13 and 58 nM for JAK1,2,3 and Tyk2, respectively. |
|
DC10612 |
Delpazolid (LCB01-0371)
Featured
|
Delpazolid (LCB01-0371) is a new oxazolidinone with cyclic amidrazone. |
|
DC8205 |
Deltarasin
Featured
|
Deltarasin is a novel and small molecule inhibitor which can inhibit the KRAS-PDEδ interaction(Kd= 41 nM. binding to PDEδ) and impairs oncogenic KRAS signalling. |
|
DC20948 |
Deltasonamide 2 |
Deltasonamide 2 (Deltasonamide-2) is a novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM. |
|
DC26004 |
delta-Valerobetaine (hydrobromide)
Featured
|
Delta-Valerobetaine (hydrobromide) is a precursor of trimethylamine N-oxide (TMAO). |
|
DC20949 |
Deltazinone 1 |
Deltazinone 1 (Deltazinone1) is a novel highly selective PDEδ inhibitor that inhibits PDEδ/Ras interaction with Kd of 8±4 nM. |
|
DC10850 |
Dencichine |
Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity. |
|
DC7199 |
Denibulin (MN-029) |
Denibulin (MN-029) is a novel vascular-disrupting agent that reversibly inhibits microtubule assembly, resulting in disruption of the cytoskeleton of tumor vascular endothelial cells. |
|
DC8712 |
Deoxycorticosterone acetate
Featured
|
Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. |
|
DC10308 |
Deoxycytidine triphosphate |
Deoxycytidine triphosphate (dCTP), a nucleoside triphosphate, is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. |
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