Inhibitors & Agonists

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Cat. No.	Product Name	Field of Application
DC21402	Deoxynyboquinone	Deoxynyboquinone, also known as DNQ, is a potent inducer of cancer cell death. DNQ potently induces death of cancer cells in culture, with IC(50) values between 16 and 210 nM. In addition, unlike the experimental therapeutic elesclomol, DNQ is still able to induce cancer cell death under hypoxic conditions. This mechanistic understanding of DNQ will allow for a more comprehensive evaluation of the potential of direct ROS generation as an anticancer strategy, and DNQ itself has potential as a novel anticancer agent.
DC23791	Deoxyspergualin	Deoxyspergualin is a derivative of the antitumor antibiotic spergualin that binds specifically to Hsc70, also inhibits poly(rC) binding protein 2 (PCBP2)..
DC8911	Deracoxib	Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).
DC10559	Derazantinib (ARQ 087) Featured	Derazantinib (Derazantinib) is an ATP competitive tyrosine kinase inhibitor; exhibits potent activity against FGFR1-3 chondrocytes with IC50s of 4.5, 1.8, and 4.5 nM, respectively.
DC24197	Derenofylline(SLV320) Featured	Derenofylline(SLV320) is a potent and selective adenosine A1 receptor antagonist (Ki values are 1, 200, 398 and 3981 nM at human A1, A3, A2A and A2B receptors respectively).
DC11402	Desidustat Featured	Desidustat is an inhibitor of HIF hydroxylase.
DC9057	Desloratadine	Desloratadine(Sch34117) is a potent antagonist for human histamine H1 receptor used to treat allergies.
DC11055	Desmethyl dabrafenib Featured	Desmethyl dabrafenib (GSK2167542, Dabrafenib metabolite M8) is the desmethyl- metabolic byproduct of Dabrafenib, ameliorates developmental pathologies of Kabuki Syndrome in vivo..
DC8833	Desmethyl VS-5584 Featured	Desmethyl VS-5584 is a PI3K/mTOR kinase inhibitor
DC9604	Desogestrel Featured	Desogestrel(Org-2969) is a third-generation 19-nortestosterone derivative progestogen; is contained in many oral contraceptive preparations, both combined (COCs) to ethinyl-estradiol (EE) or alone in a progestin-only pill (POP).
DCAPI1287	Desonide	Desonide
DC11331	Desoximetasone	Desoximetasone is a glucocorticoid.
DC9631	Desvenlafaxine (succinate hydrate)	Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
DC8097	Detomidine hydrochloride	Detomidine hydrochloride produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonist
DC20273	Deuterated AZ5104 Featured	Deuterated AZ5104 is a potent EGFR inhibitor.
DCAPI1025	Dexamethasone Featured	Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs used as an anti-inflammatory and immunosuppressant.
DC4240	Dexmedetomidine hydrochloride Featured	Dexmedetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties.
DC10231	D panthenol	Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent.
DCAPI1475	Dexrazoxane Hydrochloride	Dexrazoxane Hydrochloride
DCAPI1431	Dextromethorphan hydrobromide	Dextromethorphan hydrobromide
DC9093	Dextromethorphan HBr	Dextromethorphan hydrobromide hydrate is an antitussive drug.
DC23104	D-Fagomine	D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively.
DC22187	DFMO	DFMO (Ornithine Decarboxylase inhibitor DFMO) is an irreversible inhibitor of ornithine decarboxylase (ODC), inhibits polyamine biosynthesis.
DC22074	DFP00173 Featured	DFP00173 (DFP-00173) is a potent and selective aquaporin-3 (AQP3) inhibitor, inhibits glycerol permeability in erythrocytes with IC50 of 0.2 uM..
DC24079	DG-172 dihydrochloride Featured	DG-172 is a cutting-edge compound designed as a selective ligand for PPARβ/δ, exhibiting remarkable binding affinity with an IC50 value of 27 nM. It demonstrates robust inverse agonistic activity, positioning it as a promising candidate for research targeting PPARβ/δ signaling pathways.
DC20357	D-G23	D-G23 is a small molecule that inhibits RAD52-mediated ssDNA annealing with IC50 of 5.8 uM, binds to RAD52 with Kd of 34 uM and inhibits D-loop formation with IC50 of 7.2 uM in vitro.
DC9414	DGAT-1 inhibitor 2	DGAT-1 inhibitor 2 is an effective inhibitor of DGAT-1;antiobesity agents.
DC23686	DGAT1-IN-1	DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM..
DC20358	DGAT2 inhibitor 2	DGAT2 inhibitor 2 is a novel potent, selective DGAT2 inhibitor with IC50 of 6 nM (hDGAT2), shows no significant activity for DGAT1 (IC50>20 uM).
DCAPI1274	D-glutamine	D-glutamine is a D type stereoisomer of glutamine which is one of the 20 amino acids encoded by the standard genetic code.

Inhibitors & Agonists

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