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Membrane Transporter/Ion Channel

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Cat. No. Product Name Field of Application Chemical Structure
DC9595 E-4031 Featured E-4031 is a benzenesulfonamide antiarrhythmic agent; blocks the ATP-sensitive potassium channel.
DC9378 Efonidipine (hydrochloride monoethanolate) Featured Efonidipine(NZ-105) Hcl monoethanolate is a dual T-type and L-type calcium channel blocker (CCB).
DC8301 Elacridar Featured Elacridar is an orally selectly potent P-glycoprotein (P-gp/ABCG1) inhibitor.
DC8268 Eliprodil Featured Eliprodil is a non-competitive NMDA receptor antagonist that acts at the polyamine modulatory site.
DC8706 Emamectin Benzoate Emamectin Benzoate works as a chloride channel activator by binding gamma aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods.
DC4171 Escitalopram oxalate Featured Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
DC8821 Etifoxine Hydrochloride Featured Etifoxine Hydrochloride is a psychotropic agent with anxiolytic and anticonvulsant activity. Etifoxine Hydrochloride is an activator of GABAA R β2 and GABAA R β3.
DC9893 Evans Blue Evans Blue is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, also an AMPA/kainate receptor antagonist
DC7987 Encenicline hydrochloride (EVP-6124) Featured Encenicline hydrochloride (EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
DC10382 Farampator Featured Farampator (CX-691;Org24448) is an AMPA receptor positive modulator.
DC11309 Fipronil Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 and 1,600 nM for cockroach and rat receptors, respectively).
DC9623 Flecainide (acetate) Featured Flecainide(Tambocor) is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.
DC9451 Flumazenil Flumazenil(Ro 15-1788) is a benzodiazepine antagonist, non-selective for α1, α2, α3 or α5-containing GABAA receptors.
DC9078 Fluoxetine Hydrochloride Featured Fluoxetine HCl is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
DC4239 Flupirtine maleate Flupirtine maleateis a non-opioid, centrally acting analgesia, muscle relaxation and neuroprotection. Currently under a clinical trial (recruiting phase) as a treatment for Multiple Sclerosis and has been used as an analgesic.
DC10158 Fluralaner Featured Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
DC6917 Vonoprazan Featured For the detailed information of Vonoprazan, the solubility of Vonoprazan in water, the solubility of Vonoprazan in DMSO, the solubility of Vonoprazan in PBS buffer, the animal experiment (test) of Vonoprazan, the cell expriment (test) of Vonoprazan, the in vivo, in vitro and clinical trial test of Vonoprazan, the EC50, IC50,and affinity,of Vonoprazan, For the detailed information of Vonoprazan, the solubility of Vonoprazan in water, the solubility of Vonoprazan in DMSO, the solubility of Vonoprazan in PBS buffer, the animal experiment (test) of Vonoprazan, the cell expriment (test) of Vonoprazan, the in vivo, in vitro and clinical trial test of Vonoprazan, the EC50, IC50,and affinity,of Vonoprazan, Please contact DC Chemicals..
DC10947 FPL64176 Featured FPL64176 is a potent L-type Ca++ channel activator with EC50 of 16 nM.
DC9381 Gabapentin (hydrochloride) Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog.
DC8954 Gabapentin Featured Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain.
DC9859 GAL-021 Featured GAL-021 is a new intravenous BKCa-channel blocker.
DC7130 GBR 12935 dihydrochloride Featured GBR 12935 is a potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).
DC10721 Gefapixant(AF-219,MK-7264) Featured Gefapixant(AF-219,MK-7264) is novel P2X3 receptor antagonist.
DC10753 GLPG-1837(ABBV-974) Featured GLPG-1837(ABBV-974) is a novel cystic fibrosis transmembrane conductance regulator CFTR potentiator.
DC11678 GLPG-2222 GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM.
DC11035 GlyT1 inhibitor 46 GlyT1 inhibitor 46 is a novel potent, selective, orally available inhibitor of glycine transporter-1 (GlyT1) with IC50 of 38 and 21 nM for rat and human GlyT1, respectively.
DC10874 GlyT2-IN-1(YODA 1) Featured GlyT2-IN-1(YODA 1) is a glycine transporters GLYT2 inhibitor.
DC10907 GNE-131 Featured GNE-131 is a novel NaV1.7 inhibitor with IC50 0.003uM,improving metabolic stability,efficacy in mouse IEM model at C-plasma <2.8uM.
DC11090 GR3027 Featured GR3027 (Golexanolone) is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC.
DC8006 GS967(GS-458967) Featured GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late INa).

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