Home > Inhibitors & Agonists > Membrane Transporter/Ion Channel
Cat. No. Product name CAS No.
DC10843 CGP 52432 Featured

CGP 52432 is a potent, selective GABAB receptor antagonist (IC50 = 85 nM).

139667-74-6
DC9849 CGP37849

CGP37849 is a potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). Anticonvulsive following oral administration in vivo.

127910-31-0
DC9082 Chlorpromazine HCl Featured

Chlorpromazine Hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug.

69-09-0
DC9160 Cilnidipine Featured

Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.

132203-70-4
DC8156 CIQ Featured

CIQ is a positive allosteric modulator selective for NR2C/D containing NMDA receptors (EC50 = 2.7 and 2.8 µM for NR2C and NR2D, respectively).

486427-17-2
DC12100 Cirsimaritin

Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities.

6601-62-3
DC9118 Citalopram HBr

Citalopram hydrobromide is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has US FDA approval to treat major depression.

59729-32-7
DC7387 Clemizole Hydrochloride Featured

Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.

1163-36-6
DC8832 Clemizole (free base) Featured

Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.

442-52-4
DC9380 Cleviprex Featured

Clevidipine(Clevidipine) is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension.

167221-71-8
DC10671 CNQX disodium salt Featured

CNQX is a potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.

479347-85-8
DC10670 CNQX Featured

CNQX is a potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.

115066-14-3
DC7009 CNS-7056

CNS 7056 is a new short-acting sedative/anaesthetic that acts on GABAA receptors in the brain.

308242-62-8
DC8095 Raxatrigine hydrochloride Featured

CNV1014802(GSK-1014802) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor.

934240-31-0
DC8543 CP465022 HCl

CP 465022 hydrochloride is a selective GluR (AMPA) antagonist which is non-competitive.

199655-36-2
DC11110 CTDP-32476

CTDP-32476 is a potent and selective dopamine transporter (DAT) inhibitor and a competitive inhibitor of cocaine binding to the DAT with Ki of 12 nM.

928046-68-8
DC8665 Dantrolene sodium hemiheptahydrate

Dantrolene sodium hemiheptahydrate is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. Dantrolene sodium hemiheptahydrate is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ fro

24868-20-0
DC9116 Dantrolene sodium

Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.

14663-23-1
DC6904 DAPAGLIFLOZIN Featured

Dapagliflozin, also known as BMS-512148, is a drug used to treat type 2 diabetes approved in 2012 by FDA. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter mechanism causes blood glucose to be eliminated through the urine. In clinical trials, dapagliflozin lowered HbA1c by 0.6 versus placebo percentage points when added to metformin.

461432-26-8
DC9630 Dapoxetine (hydrochloride) Featured

Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor(SSRI).

129938-20-1
DC10073 Dasotraline Hydrochloride Featured

Dasotraline is a stereoisomer of desmethylsertraline, which is an active metabolite of the marketed selective serotonin reuptake inhibitor (SSRI) antidepressant sertraline (Zoloft) and an SNDRI similarly.

675126-08-6
DC10270 Diazoxide

Diazoxide is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions.

364-98-7
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