DC9082 |
Chlorpromazine HCl
Featured
|
Chlorpromazine Hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug. |
|
DC9160 |
Cilnidipine
Featured
|
Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity. |
|
DC8156 |
CIQ
Featured
|
CIQ is a positive allosteric modulator selective for NR2C/D containing NMDA receptors (EC50 = 2.7 and 2.8 µM for NR2C and NR2D, respectively). |
|
DC12100 |
Cirsimaritin |
Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities. |
|
DC9118 |
Citalopram HBr |
Citalopram hydrobromide is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has US FDA approval to treat major depression. |
|
DC7387 |
Clemizole Hydrochloride
Featured
|
Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication. |
|
DC8832 |
Clemizole (free base)
Featured
|
Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication. |
|
DC9380 |
Cleviprex
Featured
|
Clevidipine(Clevidipine) is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension.
|
|
DC10671 |
CNQX disodium salt
Featured
|
CNQX is a potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex. |
|
DC10670 |
CNQX
Featured
|
CNQX is a potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex. |
|
DC7009 |
CNS-7056 |
CNS 7056 is a new short-acting sedative/anaesthetic that acts on GABAA receptors in the brain. |
|
DC8095 |
Raxatrigine hydrochloride
Featured
|
CNV1014802(GSK-1014802) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor. |
|
DC8543 |
CP465022 HCl |
CP 465022 hydrochloride is a selective GluR (AMPA) antagonist which is non-competitive. |
|
DC11110 |
CTDP-32476 |
CTDP-32476 is a potent and selective dopamine transporter (DAT) inhibitor and a competitive inhibitor of cocaine binding to the DAT with Ki of 12 nM. |
|
DC8665 |
Dantrolene sodium hemiheptahydrate |
Dantrolene sodium hemiheptahydrate is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. Dantrolene sodium hemiheptahydrate is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ fro |
|
DC9116 |
Dantrolene sodium |
Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. |
|
DC6904 |
DAPAGLIFLOZIN
Featured
|
Dapagliflozin, also known as BMS-512148, is a drug used to treat type 2 diabetes approved in 2012 by FDA. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter mechanism causes blood glucose to be eliminated through the urine. In clinical trials, dapagliflozin lowered HbA1c by 0.6 versus placebo percentage points when added to metformin. |
|
DC9630 |
Dapoxetine (hydrochloride)
Featured
|
Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor(SSRI).
|
|
DC10073 |
Dasotraline Hydrochloride
Featured
|
Dasotraline is a stereoisomer of desmethylsertraline, which is an active metabolite of the marketed selective serotonin reuptake inhibitor (SSRI) antidepressant sertraline (Zoloft) and an SNDRI similarly. |
|
DC10270 |
Diazoxide |
Diazoxide is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions. |
|
DCAPI1300 |
Diclofensine (Ro 8-4650)
Featured
|
Diclofensine(Ro-8-4650) is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively. |
|
DCAPI1152 |
Diltiazem HCl (Tiazac) |
Diltiazem HCl (Tiazac) |
|
DC10446 |
(3R,4S,5S)-tert-butyl 3-Methoxy-5-Methyl-4-(MethylaMino)heptanoate hydroc hloride
Featured
|
Diltiazem hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). |
|
DC7960 |
(+)MK-801 maleate
Featured
|
Dizocilpine maleate(MK 801) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM |
|
DC9250 |
DL-AP7
Featured
|
DL-AP7 is a competitive antagonist of the ionotropic glutamate receptor, NMDA. |
|
DC10673 |
DNQX disodium salt
Featured
|
DNQX is a elective non-NMDA antagonist |
|
DC10672 |
DNQX
Featured
|
DNQX is a elective non-NMDA antagonist |
|
DC9588 |
Dofequidar (fumarate) |
Dofequidar fumarate(MS-209 fumarate), an orally active quinoline compound, has been reported to overcome MDR by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both.
|
|
DC11173 |
DRAinh-A250
Featured
|
DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA), fully and reversibly inhibits SLC26A3-mediated Cl- exchange with HCO3-, I-, and thiocyanate (SCN-) with IC50 of ~0.2 uM. |
|
DCAPI1457 |
Dronedarone Hydrochloride |
Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium and sodium and is a calcium channel protein inhibitor. |
|