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Membrane Transporter/Ion Channel

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Cat. No. Product Name Field of Application Chemical Structure
DC9082 Chlorpromazine HCl Featured Chlorpromazine Hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug.
DC9160 Cilnidipine Featured Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.
DC8156 CIQ Featured CIQ is a positive allosteric modulator selective for NR2C/D containing NMDA receptors (EC50 = 2.7 and 2.8 µM for NR2C and NR2D, respectively).
DC12100 Cirsimaritin Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities.
DC9118 Citalopram HBr Citalopram hydrobromide is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has US FDA approval to treat major depression.
DC7387 Clemizole Hydrochloride Featured Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.
DC8832 Clemizole (free base) Featured Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.
DC9380 Cleviprex Featured Clevidipine(Clevidipine) is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension.
DC10671 CNQX disodium salt Featured CNQX is a potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.
DC10670 CNQX Featured CNQX is a potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.
DC7009 CNS-7056 CNS 7056 is a new short-acting sedative/anaesthetic that acts on GABAA receptors in the brain.
DC8095 Raxatrigine hydrochloride Featured CNV1014802(GSK-1014802) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor.
DC8543 CP465022 HCl CP 465022 hydrochloride is a selective GluR (AMPA) antagonist which is non-competitive.
DC11110 CTDP-32476 CTDP-32476 is a potent and selective dopamine transporter (DAT) inhibitor and a competitive inhibitor of cocaine binding to the DAT with Ki of 12 nM.
DC8665 Dantrolene sodium hemiheptahydrate Dantrolene sodium hemiheptahydrate is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. Dantrolene sodium hemiheptahydrate is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ fro
DC9116 Dantrolene sodium Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.
DC6904 DAPAGLIFLOZIN Featured Dapagliflozin, also known as BMS-512148, is a drug used to treat type 2 diabetes approved in 2012 by FDA. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter mechanism causes blood glucose to be eliminated through the urine. In clinical trials, dapagliflozin lowered HbA1c by 0.6 versus placebo percentage points when added to metformin.
DC9630 Dapoxetine (hydrochloride) Featured Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor(SSRI).
DC10073 Dasotraline Hydrochloride Featured Dasotraline is a stereoisomer of desmethylsertraline, which is an active metabolite of the marketed selective serotonin reuptake inhibitor (SSRI) antidepressant sertraline (Zoloft) and an SNDRI similarly.
DC10270 Diazoxide Diazoxide is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions.
DCAPI1300 Diclofensine (Ro 8-4650) Featured Diclofensine(Ro-8-4650) is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively.
DCAPI1152 Diltiazem HCl (Tiazac) Diltiazem HCl (Tiazac)
DC10446 (3R,4S,5S)-tert-butyl 3-Methoxy-5-Methyl-4-(MethylaMino)heptanoate hydroc hloride Featured Diltiazem hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist).
DC7960 (+)MK-801 maleate Featured Dizocilpine maleate(MK 801) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM
DC9250 DL-AP7 Featured DL-AP7 is a competitive antagonist of the ionotropic glutamate receptor, NMDA.
DC10673 DNQX disodium salt Featured DNQX is a elective non-NMDA antagonist
DC10672 DNQX Featured DNQX is a elective non-NMDA antagonist
DC9588 Dofequidar (fumarate) Dofequidar fumarate(MS-209 fumarate), an orally active quinoline compound, has been reported to overcome MDR by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both.
DC11173 DRAinh-A250 Featured DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA), fully and reversibly inhibits SLC26A3-mediated Cl- exchange with HCO3-, I-, and thiocyanate (SCN-) with IC50 of ~0.2 uM.
DCAPI1457 Dronedarone Hydrochloride Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium and sodium and is a calcium channel protein inhibitor.

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