Cat. No. | Product name | CAS No. |
DC11508 |
AC1903
Featured
AC1903 is a specific and selective inhibitor of TRPC5 and has podocyte-protective properties. AC1903 does no effects on TRPC4 or TRPC6 currents and shows no off-target effects in kinase profiling assays. AC1903 suppresses severe proteinuria and prevents podocyte loss in focal segmental glomerulosclerosis (FSGS) rat model. |
831234-13-0 |
DC7783 |
AF-353(Ro-4)
Featured
AF-353 is a novel, orally bioavailable, highly potent and selective P2X3/P2X2/3 receptor antagonist. |
865305-30-2 |
DC9026 |
Afloqualone
Afloqualone is a agonist of GABA receptor . |
56287-74-2 |
DC9764 |
Afoxolaner
Featured
Afoxolaner is an isoxazoline that inhibits insect and acarine ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), blocking pre and post synaptic transfer of chloride ions across cell membranes. |
1093861-60-9 |
DC10311 |
Allopregnanolone
Featured
Allopregnanolone is a progesterone metabolite. Allopregnanolone is an allosteric modulator of the GABA receptor. |
516-54-1 |
DC11840 |
ALX-1393
ALX-1393 (ALX 1393, ALX1393) is a potent, specific GlyT2 inhibitor with Ki of <1 uM. |
949164-09-4 |
DC11289 |
AM-0466
Featured
AM-0466 is a potent and selective NaV1.7 Inhibitor (Nav 1.7 IC50 = 21 nM; Nav 1.5 IC50 =>30.0 uM. PXR = 22% @10 uM; CYP 2C9 IC50 = 4.6 uM; CYP3A4 TDI IC50 =>50.0 uM.). |
1642113-59-4 |
DC9909 |
AM2099
Featured
AM-2099 is a potent and selective NaV1.7 Inhibitor. |
1443373-17-8 |
DC11239 |
AMG-333
Featured
AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM. |
1416799-28-4 |
DC7055 |
AMG517
Featured
AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM. |
659730-32-2 |
DC10132 |
AMG9810
Featured
AMG9810 is a potent and selective, competitive vanilloid TRPV1 receptor antagonist (IC50 = 17 nM). |
545395-94-6 |
DC9189 |
Amiodarone HCl
Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM. |
19774-82-4 |
DC5075 |
BDP-12(Ampalex)
Featured
Ampalex (Ampakine CX516) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). |
154235-83-3 |
DC11076 |
Ampreloxetine
Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively. |
1227056-84-9 |
DC11657 |
PPT(Propyl pyrazole triol )
Featured
Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%). |
263717-53-9 |
DC11649 |
Jamaicin (AnCoA4)
Featured
AnCoA4 (AnCoA-4, AnCoA 4) is a potent Orai1 channel inhibitor that inhibits store-operated calcium (SOC) with EC50 of 0.88 uM. |
24211-36-7 |
DC8976 |
Aniracetam
Aniracetam(Ro 13-5057) is a nootropics and neuroprotective drug, which is selectively modulates the AMPA receptor and nAChR. |
72432-10-1 |
DC11196 |
AP14145
AP14145 (AP-14145) is a potent, selective negative allosteric modulator of KCa2.2 and KCa2.3 with equal potency (IC50=1.1±0.3 uM). |
1446770-54-2 |
DC10558 |
ASP 7663
Featured
ASP 7663 is a selective TRPA1 activator (EC50 values are ~0.5 μM in human, mouse and rat). |
1190217-35-6 |
DC9034 |
Atomoxetine HCl
Atomoxetine Hcl(LY 139603; Tomoxetine Hcl) is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). |
82248-59-7 |
DC11999 |
AUT-1
Featured
AUT-1 is a novel specific, cell permeant modulator of Kv3 channels with EC50 of 4.7 and 4.9 uM for Kv3.1b and Kv3.2a, respectively. |
1311136-84-1 |
DC9263 |
AZD-3965
Featured
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM. |
1448671-31-5 |