| DC22566 |
Glesatinib hydrochloride |
Glesatinib (MGCD-265) is a tyrosine kinase inhibitor that potently and selectively inhibits Met and Axl kinase.. |
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| DC25053 |
Glesatinib |
Glesatinib (MGCD-265) is a tyrosine kinase inhibitor that potently and selectively inhibits Met and Axl kinase.. |
|
| DC12257 |
Gln-AMS TFA |
Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. Gln-AMS inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 µM. |
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| DC12354 |
Gln-AMS |
Gln-AMS is an aminoacyl-tRNA synthetases (AARS) inhibitor, which binds the A-domain within the NRPS enzymes. |
|
| DC12223 |
GLP-1 receptor agonist-1 |
GLP-1 receptor agonist-1 is a glucagon-like peptide-1 receptor (GLP-1R) agonist. |
|
| DC10319 |
GLP-17-3 |
GLP-1(7-36) is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells. |
|
| DC11296 |
GLP-26
Featured
|
GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM. |
|
| DC21051 |
GLPG 0974 |
GLPG 0974 is a potent, selective free fatty acid receptor 2 (FFA2, GPR43) antagonist with IC50 of 95 nM. |
|
| DC11678 |
GLPG-2222 |
GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM. |
|
| DC26048 |
GLS1 Inhibitor
Featured
|
GLS1 inhibitor is an inhibitor of glutaminase 1 |
|
| DC21052 |
GLS 4(Morphothiadin)
Featured
|
GLS4 (Morphothiadin) is a potent inhibitor of HBV capsid assembly, inhibits HBV replication (EC50=62.24 nM) and reduces HBV-DNA levels in HepG.2.2.15 cells (IC50=14 nM), shows efficacy against ADV-resistant HBV mutations. |
|
| DC20026 |
Glucokinase activator 1 |
Glucokinase activator 1 is a liver-directed glucokinase activator with an EC50 of 34 nM. |
|
| DC11543 |
Glumetinib
Featured
|
Glumetinib (SCC 244) is a novel potent and highly selective inhibitor of c-Met kinase with IC50 of 0.42 nM. |
|
| DC12236 |
Glycodeoxycholate Sodium |
Glycodeoxycholate Sodium is a bile salt. |
|
| DC12082 |
Glycodeoxycholic acid monohydrate |
Glycodeoxycholic acid monohydrate is a nuclear receptor ligand. |
|
| DC12229 |
Glycogen |
Glycogen is a glycolytic intermediates and high-energy phosphates that can serve as a form of energy storage in humans, animals, fungi, and bacteria. |
|
| DC20889 |
Glycopyrronium bromide |
Glycopyrronium bromide (CHF 5259) is a peripherally-acting quaternary ammonium antimuscarinic agent with little or no central nervous system activity. |
|
| DC11035 |
GlyT1 inhibitor 46 |
GlyT1 inhibitor 46 is a novel potent, selective, orally available inhibitor of glycine transporter-1 (GlyT1) with IC50 of 38 and 21 nM for rat and human GlyT1, respectively. |
|
| DC20113 |
Gly-β-MCA |
Gly-β-MCA, a bile acid, is a potent, sable, intestine-selective and oral bioactive farnesoid X receptor (FXR) inhibitor that may be a candidate for the treatment of metabolic disorders. |
|
| DC21568 |
GMI-1070 |
GMI-1070 (Rivipansel, PF-06460031) is a novel small molecule glycomimetic pan-Selectin antagonist with IC50 of 4.3 uM, 423 uM and 337 uM for E-selectin, P-selectin and L-selectin, respectively. |
|
| DC11070 |
GNA002 |
GNA002 (GNA-002) is a gambogenic acid (GNA) derivative that specifically and covalently binds to Cys668 within the EZH2-SET domain, trigges EZH2 degradation (IC50=1.1 uM) through COOH terminus of Hsp70-interacting protein (CHIP)-mediated ubiquitination. |
|
| DC12343 |
GNE 220 Hydrochloride |
GNE 220 (Hydrochloride) is a potent and selective inhibitor of MAP4K4, with an IC50 of 7 nM. |
|
| DC23124 |
GNE-0439 |
GNE-0439 is a novel potent, selective inhibitor of Nav1.7 channel with IC50 of 0.34 uM, shows high selectivity over Nav1.5 (IC50=38.3 uM). |
|
| DC22532 |
GNE-049 |
GNE-049 (GNE049) is a potent, selective, orally available inhibitor of CBP/p300 bromodomain with biochemical IC50 of 1.1/2.3 nM, respectively. |
|
| DC23805 |
GNE-220 |
GNE-220 is a potent and selective inhibitor of MAP4K4 with IC50 of 7 nM, also inhibits MINK (MAP4K6), DMPK and KHS1 (MAP4K5) with IC50 of 9 nM, 476 nM and 1,110 nM. |
|
| DC9934 |
GNE-272 |
GNE-272 is a in Vivo Probe for the Bromodomains of CBP/EP300. |
|
| DC23337 |
GNE-2861 |
GNE-2861 is a potent, selective group II PAK (PAK4/5/6) inhibitor with IC50 of 7.5/126/36 nM, respectively, shows selectivity over group I PAKs (IC50=5.42/0.97/>10 uM for PAK1/2/3). |
|
| DC21057 |
GNE-293 |
GNE-293 is a potent and selective PI3Kδ inhibitor with Ki of 0.47 nM, displays 256, 420, 219-fold selectivity over PI3Kα, PI3Kβ, PI3Kγ, respectively. |
|
| DC11845 |
GNE-3500 |
GNE-3500 (GNE3500) is a potent, selective, and orally bioavailable RORγ inhibitor with IC50 of 47 nM in IL-17 promoter assays. |
|
| DC12313 |
GNE-371 |
GNE-371 is a potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like, with an IC50 of 10 nM for TAF1(2). |
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