Cat. No. | Product name | CAS No. |
DC22050 |
CCI-006
CCI-006 (CCI 006) is a novel inhibitor of MLL-rearranged and CALM-AF10 translocated leukemias that share common leukemogenic pathways. |
292053-42-0 |
DC22049 |
CCI-007
CCI-007 (CCI 007) is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485. |
939228-52-1 |
DC26030 |
CCMI
Featured
CCMI is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (nAChR). |
917837-54-8 |
DC12639 |
CCR1 inhibitor 19e
CCR1 inhibitor 19e is a novel potent, selective CCR1 antagonist with IC50 of 6.8 nM, inhibits CCR1chemotaxis in THP-1 cells with IC50 of 28 nM.. |
1220026-26-5 |
DC23528 |
CCR10 antagonist 1
CCR10 antagonist 1 is a potent, selective CCR10 antagonist with IC50 of 690 nM. |
1191031-97-6 |
DC12177 |
CCR2 antagonist 1
CCR2 antagonist 1 is a high-affinity and long-residence-time CCR2 antagonist, with a Ki of 2.4 nM. |
1683534-96-4 |
DC11204 |
CCR6 inhibitor 35
CCR6 inhibitor 35 is a potent and selective CCR6 inhibitor with IC50 of 6.0 nM (hCCR6). |
|
DC20876 |
CCT 068127
CCT 068127 (CCT68127) is a novel potent inhibitor of CDK2 and CDK9 with IC50 of 10 and 90 nM for CDK2/E and CDK9/T, respectively. |
660822-23-1 |
DC8776 |
CCT 137690
CCT 137690 is a potent inhibitor of Aurora kinases (IC50 values are 0.015, 0.019 and 0.025 μM at Aurora A, Aurora C and Aurora B respectively). |
1095382-05-0 |
DC20875 |
CCT 365623 hydrochloride
CCT 365623 (CCT365623) hydrochloride is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM. |
2126136-98-7 |
DC20874 |
CCT 365623
CCT 365623(CCT365623, CCT-365623) is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM. |
2126134-01-6 |
DC7803 |
CCT007093
Featured
CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM. |
176957-55-4 |
DC22464 |
CCT-018159
CCT-01815 is a novel potent inhibitor of Hsp90 ATPase activity with IC50 of 7.1 uM. |
171009-07-7 |
DC12283 |
CCT020312
CCT020312 is capable of delivering potent, and eukaryotic initiation factor 2-alpha kinase 3 (EIF2AK3) selective, proliferation control and also is an activator of RNA-like endoplasmic reticulum kinase (PERK). |
324759-76-4 |
DC20872 |
CCT-031374
CCT-031374 is a selective β-catenin signaling inhibitor with IC50 of 6.1 uM. |
442535-46-8 |
DC23168 |
CCT128930
CCT128930 is a potent, selective, ATP-competitive AKT inhibitor with IC50 of 6 nM (AKT2), 28-fold selectivity over the closely related PKA. |
885499-61-6 |
DC23163 |
CCT129202
CCT129202 is a potent, selective, ATP-competitive pan-Aurora kinase inhibitor with IC50 of 42, 198 and 227 nM for Aurora A, Aurora B and Aurora C, respectively. |
942947-93-5 |
DC23828 |
CCT241161
CCT241161 is a potent pan-RAF inhibitor with IC50 of 30, 15 and 6 nM for BRAF, V600E-BRAF and C-RAF, also potently inhibits SRC and LCK (IC50=10 and 3 nM, respectively).. |
1163719-91-2 |
DC9399 |
CCT241533 (hydrochloride)
CCT241533 Hcl is a potent serine/threonine checkpoint kinase (Chk2) inhibitor with IC50 of 3 nM; shows minimal cross-reactivity against a panel of kinases at 1 uM. |
1431697-96-9 |
DC9968 |
CCT251545
Featured
CCT251545 is an orally bioavailable and potent inhibitor of WNT signaling with IC50 value of 5 nM. |
1661839-45-7 |
DC9969 |
CCT251921
CCT251921 is a potent, selective, and orally bioavailable small-molecule modulators of the mediator complex-associated kinases CDK8 and CDK19. (IC50 data: CDK8:=2.3 nM; CDK19 = 2.6 nM). |
1607837-31-9 |
DC11679 |
CCT-367766
Featured
CCT367766 is a potent and the third generation heterobifunctional and PROTAC-based pirin targeting protein degradation probe (PDP), depletes pirin protein expression at low concentration. CCT367766 exhibits a moderate affinity for the CRBN-DDB1 complex with an IC50 value of 490 nM. CCT367766 reveals a good affinity for the recombinant pirin and CRBN with Kd values of 55 nM and 120 nM, respectively. CCT367766 provides a potential chemical tool to study a largely unexplored protein[1]. |
2229856-58-8 |