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Cat. No.	Product Name	Field of Application
DC22698	CE-326597	A potent, selective agonist of the human and rat CCK1 receptor with Ki of 36 nM.
DC20295	2-PCCA	A potent, selective agonist of the orphan GPR88 receptor with EC50 of 877 nM.
DC24029	PF-4840154	A potent, selective agonist of the rat (EC50=97 nM) and human (EC50=23 nM) TRPA1 channel.
DC23831	TASP0382088	A potent, selective ALK5 inhibitor with IC50 of 4.8 nM, >100-fold selectivity over 95 different kinases.
DC20564	TBBz Featured	A potent, selective and ATP-competitive CK2 inhibitor with Ki of 0.5-1 uM.
DC20686	AS602868	A potent, selective and ATP-competitive inhibitor of IKK2 with IC50 of 60 nM and Ki of 20 nM, also interfers directly with FLT3 kinase activation.
DC22817	RUSKI-201	A potent, selective and cell active Hedgehog acyltransferase (Hhat) inhibitor with IC50 of 0.87 uM.
DC11820	A-893	A potent, selective and cell active lysine methyltransferase SMYD2 inhibitor with IC50 of 2.8 nM.
DC22867	HR22C16	A potent, selective and cell permeable inhibitor of mitotic kinesin Eg5 with IC50 of 0.8 uM, does not interact with other microtubule motor proteins.
DC20309	ANTISAUVAGINE-30 Featured	A potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist with Ki of 1.4 nM, 100-fold selectiivity over CRF1.
DC11979	SB 332235	A potent, selective and competitive CXCR2 inhibitor that selectively inhibits CXCR2-mediated recruitment of β-arrestin-2 with pKi of 8.92.
DC11755	L-732138 Featured	A potent, selective and competitive NK1 receptor antagonist with IC50 of 2.3 nM.
DC22763	Rilapladib	A potent, selective and oral lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.23 nM, for the treatment of Alzheimer's disease and atherosclerosis..
DC21210	Rolofylline	A potent, selective and orally active adenosine A1 receptor antagonist with Ki of 1.3 nM.
DC21827	XE 991 dihydrochloride Featured	A potent, selective and orally active blocker of voltage-gated potassium channels Kv7 (KCNQ) that blocks KCNQ1, KCNQ2 and KCNQ2+KCNQ3 with Kd of 0.78, 0.7 and 0.6 uM, respectively.
DC23371	NI-42 Featured	NI-42 is a potent, selective and orally active BRPF1 bromodomain inhibitor with IC50 of 7.9 nM, with excellent selectivity over nonclass IV BRDs; weakly inhibits BRPF2 (BRD1), BRPF3, BRD9 and BRD4 (BD1) with IC50 of 48, 260, 310 and 4500 nM respectively, and no activity for ATAD2A/2B (IC50>100 uM); shows a modest (GI50=1-10 uM) and selective inhibition of proliferation of certain cancer lines, particularly those lines exhibiting monocytic lineage differentiation; a novel, structurally orthogonal chemical probe for the BRPFs suitable for cellular and in vivo studies.
DC11710	GDC-0425	A potent, selective and orally active Chk1 inhibitor.
DC24158	Rofecoxib	A potent, selective and orally active COX-2 inhibitor with IC50 of 26 nM for inhibition of the COX-2-dependent production of PGE2 in human osteosarcoma cells.
DC20810	Pexacerfont	A potent, selective and orally active CRF1 receptor antagonist with IC50 of 6.1 nM, >1,000-fold selectivity over CRF-binding protein and biogenic amine receptors.
DC20923	CP 376395 hydrochloride	A potent, selective and orally active CRF1 receptor antagonist with Ki of 12 nM, shows no affinity for CRF2 receptor (Ki>10 uM).
DC20689	ASB 14780	A potent, selective and orally active cytosolic phospholipase A2α (cPLA2α) inhibitor with IC50 of 20 nM.
DC11868	Freselestat	A potent, selective and orally active human neutrophil elastase (HNE) inhibitor with Ki of 12 nM.
DC21689	SR 142948A Featured	A potent, selective and orally active neurotensin receptor antagonist with IC50 of 1.19 nM.
DC23621	YM543	A potent, selective and orally active SGLT2 inhibitor with IC50 of 8.9 nM, 280-fold selectivity over SGLT1.
DC11514	Atogepant	A potent, selective and orally available CGRP receptor antagonist for the prevention of migraine. Migraine.
DC21842	Darexaban	A potent, selective and orally available factor Xa (FXa) inhibitor with IC50 of 54.6 nM.
DC21718	T-3364366	A potent, selective and orally available inhibitor of delta-5 desaturase (D5D) with Ki of <2.7 nM and IC50 of 19 nM, with excellent selectivity over D6D and SCD.
DC20768	Tonapofylline	A potent, selective and orally bioavailable adenosine A1 (A1A) receptor antagonist with Ki of 7 nM.
DC22682	INCB9471	A potent, selective and orally bioavailable CCR5 antagonist IC50 of 6.5 nM, Kd of 3.1 nM in human PBMCs.
DC23643	JNJ 54166060	A potent, selective and orally bioavailable P2X7 receptor with IC50 of 4 nM and 115 nM for hP2X7 and rP2X7, respectively.

Novel inhibitors

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