| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21600 | S1P Lyase inhibitor 31 | A potent, selective and orally bioavailable S1P lyase (S1PL) inhibitor with enzyme IC50 of 44 nM, cell IC50 of 110 nM. |
|
| DC21464 | Eribaxaban | A potent, selective and orally efficacious factor Xa (FXa) inhibitor with IC50 of 0.32 nM. |
|
| DC25047 | Calphostin C | A potent, selective and photo-dependent inhibitor of PKC with IC50 of 50 nM. |
|
| DC11511 | A-485 Featured | A potent, selective and, cell and in vivo active p300/CBP catalytic inhibitor with IC50 of 9.8/2.6 nM. |
|
| DC20602 | 5F 203 Featured | A potent, selective antitumour agent through activation the aryl hydrocarbon receptor (AhR) pathway. |
|
| DC21576 | RO-5508887 | A potent, selective BACE inhibitor with IC50 of 30 nM for BACE1, equally potent against BACE2 (IC50=40 nM) but >1,000-fold selectivity over cathepsin D, cathepsin E, pepsin and renin. |
|
| DC21103 | GW405833 hydrochloride | A potent, selective cannabinoid receptor CB2 agonist with Ki of 3.6 nM, 1200-fold selectivity over CB1. |
|
| DC20658 | AM1241 Featured | A potent, selective cannabinoid receptor CB2 agonist with Ki of 7.1 nM, >80-fold selectivity over CB1 receptors in radioligand binding assay. |
|
| DC21376 | NESS-0327 | A potent, selective CB1 cannabinoid receptor antagonist with Ki of 350 fM, >60,000-fold selective for the CB1 receptor versus CB2 receptor (Ki=21 nM). |
|
| DC23357 | CBP bromodomain inhibitor | a potent, selective CBP bromodomain inhibitor with IC50 of 69 nM, displays exquisite selectivity over BRD4(1) (IC50=18 uM) and the broader bromodomain family.. |
|
| DC22697 | PF-04756956 | A potent, selective CCK1 receptor agonist with EC50 of 0.47 nM. |
|
| DC21393 | nNOS-IN-25 | A potent, selective cell permeable neuronal nitric oxide synthase (nNOS) inhibitor with Ki of 30 nM. |
|
| DC11519 | Ceclazepide | A potent, selective cholecystokinin receptor CCK2 antagonist for treatment of gastroesophageal reflux disease (GERD).. |
|
| DC20633 | ACG-548B | A potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM, >400-fold selectivity over ChoKβ. |
|
| DC20632 | ACG-416B | A potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.13 uM, >385-fold selectivity over ChoKβ. |
|
| DC21741 | RSM-932A | A potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 1.0 uM, 33-fold selectivity over ChoKβ. |
|
| DC22917 | SCH 79797 dihydrochloride Featured | A potent, selective competitive and nonpeptide PAR-1 antagonist with IC50 of 70 nM. |
|
| DC20580 | Vitacoxib | A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL). |
|
| DC11675 | Synta-66 | A potent, selective CRAC channel Orai1 blocker with IC50 of 3 uM. |
|
| DC22418 | CCX-771 | A potent, selective CXCR7 antagonist with IC50 of 4.1 nM. |
|
| DC22912 | SCH39166 | A potent, selective D1 dopamine receptor antagonist with Ki of 3.6 nM, >300-fold selectivity over D2 and 5-HT2 receptors. |
|
| DC11897 | Garvagliptin | A potent, selective dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment for type 2 diabetes.. |
|
| DC12015 | SKF 83566 hydrobromide | A potent, selective dopamine D1 receptor antagonist with Ki of 0.56 nM. |
|
| DC22910 | ABT-724 | A potent, selective dopamine D4 receptor agonist that activates human dopamine D4 receptors with EC50 of 12.4 nM, with no effect on dopamine D1, D2, D3, or D5 receptors. |
|
| DC22909 | ABT-724 trihydrochloride | A potent, selective dopamine D4 receptor agonist that activates human dopamine D4 receptors with EC50 of 12.4 nM, with no effect on dopamine D1, D2, D3, or D5 receptors. |
|
| DC11973 | A-412997 | A potent, selective dopamine D4 receptor agonist with Ki of 12.1 and 7.9 nM for rat and human D4 receptors, respectively. |
|
| DC11866 | AZD 3147 Featured | A potent, selective dual mTORC1 and mTORC2 inhibitor with enzyme IC50 of 1.5 nM. |
|
| DC22586 | AZD9496 maleate | A potent, selective estrogen receptor downregulator (SERD) with ER downregulation pIC50 of 9.68. |
|
| DC20378 | FABP4 inhibitor 1 | A potent, selective FABP4 inhibitor with Ki of 30 nM.. |
|
| DC11956 | CCG 258748 | A potent, selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 8 nM. |
|
