| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11572 | E3 Ligand-Linker Conjugate 6 Featured | An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC11573 | E3 Ligand-Linker Conjugate 7 Featured | An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC11574 | E3 Ligand-Linker Conjugate 8 Featured | An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC11576 | E3 Ligand-Linker Conjugate 10 | An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC22869 | E3 Ligand-Linker Conjugate 3(E3 Ligase Ligand-Linker Conjugates 19) Featured | An E3 ligase ligand-linker conjugate for PROTAC. |
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| DC11569 | E3 Ligand-Linker Conjugate 4 | An E3 ligase ligand-linker conjugate for PROTAC... |
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| DC26084 | LE-135 Featured | LE135 is a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels. |
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| DC22495 | Lenampicillin hydrochloride | An efficient prodrug of ampicillin with enhanced absorption and decreased side effects.. |
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| DC24168 | (R)-(-)-Ibuprofen Featured | An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids. |
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| DC22361 | (S)-(+)-Ibuprofen | An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form. |
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| DC24138 | Synaptamide | An endogenous DHA metabolite that promotes neurite growth, synaptogenesis, and synaptic function both in vitro and in vivo. |
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| DC11747 | Iperoxo | Iperoxo is a superagonist of the muscarinic acetylcholine receptors and an OxotremorineM analog. |
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| DC23324 | C-1311 dihydrochloride | An imidazoacridinone analogue with potent in vivo antitumour activity, inhibits the catalytic activity of Topoisomerase II. |
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| DC25076 | Imazamox | An imidazolinone herbicide that effectively controls a broad spectrum of weed species.. |
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| DC23914 | Thymalfasin GMP grade Featured | An immunoactive peptide that has been shown to inhibit cell proliferation and induce apoptosis in human leukemia, non-small cell lung cancer, melanoma, and other human cancers. |
|
| DC1001 | FK-506 (Tacrolimus) Featured | Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties. |
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| DC22995 | IRES-J007 Featured | IRES-J007 ia an improved IRES inhibitor that blocks IRES-hnRNP A1 binding; binds to a small pocket structure within the RRM-containing fragment of hnRNP A1 (UP1 fragment), inhibits cyclin D1 and c-MYC IRES activity to a greater extent compared with C11 (IRES-C11); significantly reduces tumor growth of GBM xenografts in mice, and markedly reduces the mRNA translational state of cyclin D1 and c-MYC transcripts combined with PP242. |
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| DC22542 | Roflumilast Impurity E | An impurity of Roflumilast, which is a selective and long-acting inhibitor of PDE-4 with IC50 value of 0.8 nM.. |
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| DC20988 | Indirubin E804 | An indirubin derivative that potently blocks constitutive STAT3 signaling in human breast and prostate cancer cells, directly inhibits Src kinase activity (IC50=0.43 uM) in vitro. |
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| DC22998 | MIND4-17 | An inducer of NRF2 that selectively activates NRF2 signaling with CD value (The concentration that doubles the specific activity) of 0.18 uM. |
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| DC23993 | Aldose reductase-IN-1 | An inhibitor of aldose reductase with IC50 of 28.9 pM. |
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| DC22549 | KDM5A-IN-1 | An inhibitor of histone demethylase.. |
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| DC6311 | Pomalidomide Featured | An inhibitor of LPS-induced TNFαrelease.Pomalidomide is thalidomide derivative that displays inhibition of LPS-induced TNFα release. Shows immunomodulator and anticancer effects. |
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| DC23937 | SIBA | An inhibitor of the IMP-selective cytosolic 5'-nucleotidase (IC50=2-6 mM). |
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| DC22360 | Valifenalate | An insecticide agent that is approved for application on high-value crops such as grapes, tomatoes and other vegetables.. |
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| DC24195 | Benoxafos | An insecticide agent.. |
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| DC24177 | Mitiglinide calcium hydrate Featured | An insulin secretion stimulator by closing the ATP-sensitive potassium KATP channels in pancreatic β cells. |
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| DC24164 | Proparacaine hydrochloride | An irreversible local anesthetic. |
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| DC22612 | Afatinib Featured | An irreversible, dual EGFR/HER2 inhibitor with IC50 of 0.5/0.4/10/14 nM for wt EGFR/EGFR L858R/EGFR L858R+T790M/HER2 respectively. |
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| DC11640 | PK-11195 Featured | PK 11195 is a ligand of translocator protein. It targets Leishmania chemotherapy (IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively). |
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