| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21406 | AZ-1355 | AZ-1355 is an effctive lipid-lowering compound that inhibits platelet aggregation in vivo and elevates the prostaglandin I2/thromboxane A2 ratio in vitro.. |
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| DC20712 | AZ13705339 Featured | AZ13705339 is a potent, selective PAK1 inhibitor with IC50 of 0.33 nM, displays 14-, 470-, 4100- and 2600-fold selectivity over Src, FGFR1, KDR and PAK4. |
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| DC20713 | AZ13711265 | AZ13711265 is a potent, selective, in vivo active PAK1 inhibitor with IC50 of 0.58 nM, displays 880-, 2100- and 90-fold selectivity over Src, FGFR1, KDR and PAK4. |
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| DC23484 | AZ1729 | AZ1729 is a novel direct, positive allosteric modulator of fatty acid receptor FFA2 (pEC50=6.9), selectively activates Gi signaling but lacks the capacity to activate FFA2 Gq/G11-mediated signaling pathways. |
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| DC7746 | AZ191 Featured | AZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM, about 5- and 110-fold selectivity over DYRK1A and DYRK2, respectively. |
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| DC20315 | AZ-2 | AZ-2 is a small molecule inducer of ABCA1 and apoE that act through indirect activation of the LXR pathway, shows purinergic receptor P2X7 antagonist activity. |
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| DC7906 | AZ20 Featured | AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM, 8-fold selectivity over mTOR. |
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| DC23855 | AZ-23 | AZ-23 is a potent, selective, orally bioavailable Trk kinase inhibitor with IC50 of 2 and 8 nM for TrkA and TrkB, respectively. |
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| DC12376 | AZ304 Featured | AZ304 is a novel potent, dual BRAF inhibitor targeting the kinase domains of wild type BRAF, V600E mutant BRAF and wild type CRAF with IC50 of 79 nM, 38 nM and 68 nM, respectively. |
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| DC10906 | AZ31 Featured | AZ31 is a novel ATM inhibitor. |
|
| DC7072 | AZ3146 Featured | AZ3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM); less potent to FAK, JNK1, JNK2, and Kit. |
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| DC10891 | AZ-32 Featured | AZ32 is an orally bioavailable and blood-brain-barrier penetrating ATM inhibitor (AZ32) that radiosensitizes intracranial gliomas in mice. |
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| DC9667 | AZ-33(AZ33) Featured | AZ-33 is a inhibitor of LDH-A with an IC50 of 0.5 μM. |
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| DC10879 | AZ3451 Featured | AZ3451 is a potent and selective allosteric antagonist of protease-activated receptor 2 (PAR2) |
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| DC20715 | AZ-4217 | AZ-4217 is a potent and selective, orally active, brain-permeable BACE1 inhibitor with IC50 of 160 pM in human SH-SY5Y cells. |
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| DC22293 | AZ-505 ditrifluoroacetate Featured | AZ505 ditrifluoroacetate is a potent and selective SMYD2 inhibitor with IC50 of 0.12 μM. |
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| DC8537 | AZ505 Featured | AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=0.12 uM) with potential anticancer activity, >600 fold than SMYD3(IC50>83.3 uM); DOT1L(IC50>83.3 uM);EZH2(IC50>83.3 uM). |
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| DC8052 | AZ5104 Featured | AZ5104 is an active circulating metabolite of AZD9291. |
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| DC7926 | AZ-6102 Featured | AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows 5 nM Wnt pathway inhibition in DLD-1 cells. |
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| DC10985 | AZ6197 | AZ6197 (AZ-6197) is a potent, selective, reversible inhibitor of ERK1/2 with IC50 of <0.3 nM (ERK2), inhibits pERK/pRSK with IC50 of 12/62 nM in A375 cells, respectively. |
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| DC8842 | AZ-7371（DprE1-IN-1） Featured | AZ-7371（DprE1-IN-1） is a novel non-covalent DprE1 inhibitor. |
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| DC12274 | AZ82 | AZ82 is a selective HSET/KIFC1 inhibitor, with a Ki of 43 nM and an IC50 of 300 nM for KIFC1. |
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| DC12677 | AZ876 Featured | AZ876 is a novel high-affinity LXR agonist. |
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| DC11742 | AZ-8838 | AZ-8838 (AZ8838) is a potent, and selective PAR2 antagonist with Kd of 125 nM. |
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| DC23407 | AZ8838 racemate | AZ8838 racemate(AZ-8838 racemate) is the racemate form of AZ8838, which is a potent, and selective PAR2 antagonist with Kd of 125 nM.. |
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| DC10056 | AZ9482 Featured | AZ9482, a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. |
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| DC8713 | Azaperone | Azaperone acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in |
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| DCAPI1427 | Azasetron HCL | Azasetron Hydrochloride is a 5-HT3 receptor antagonist which is used as an anti-emetic. |
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| DC9469 | Azatadine (dimaleate) | Azatadine dimaleate is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively. |
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| DCAPI1182 | Azathioprine (Azasan, Imuran) Featured | Azathioprine (Azasan, Imuran) is the analytical standard of Azathioprine. This product is intended for research and analytical applications. Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis. |
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