| DC22051 |
CDD-450 |
CDD-450 is an unique inhibitor that selectively blocks p38α activation of proinflammatory kinase MAPK-MK2 while sparing p38α activation of PRAK and ATF2. |
|
| DC8361 |
CDDO(Bardoxolone; RTA 401)
Featured
|
CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. |
|
| DC12026 |
CDDO-2P-Imidazolide
Featured
|
CDDO-2P-Im is a new analogue of CDDO-Imidazolid,showing better bioactive than CDDO-Imidazolid. |
|
| DC12027 |
CDDO-3P-Imidazolide
Featured
|
CDDO-3P-Im is a new analogue of CDDO-Imidazolid,showing better bioactive than CDDO-Imidazolid. |
|
| DC12025 |
CDDO imidazolide
Featured
|
CDDO-imidazolide is a potent inducer of heme oxygenase-1 and Nrf2/ARE signaling,with potent antiproliferative, differentiating, and anti-inflammatory activities. |
|
| DC9277 |
C-DIM12
Featured
|
C-DIM12 is a novel synthetic activator of Nurr1. |
|
| DC10792 |
DIM-C-pPhOCH3(C-DIM5)
Featured
|
C-DIM5 is a Nur77 agonist. Activation of the orphan nuclear receptor Nur77 by C-DIM5 is associated with decreased cancer cell survival, |
|
| DC11158 |
CDK12 inhibitor 2 |
CDK12 inhibitor 2 is a potent, selective, non-covalent CDK12 inhibitor with IC50 of 52 nM, displays >192-fold selectivity over CDK2/7/8/9. |
|
| DC11872 |
CDK12 inhibitor E9 S-isomer |
CDK12 inhibitor E9 S-isomer (E9, CDK12-IN-E9) is a clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux. |
|
| DC20334 |
CDK2 inhibitor 73
Featured
|
CDK2 inhibitor 73 is a potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).. |
|
| DC8596 |
Cdk4/6 Inhibitor IV |
Cdk4/6 Inhibitor IV is a cell-permeable triaminopyrimidine compound acting as a reversible and ATP-competitive inhibitor of Cdk4/6 (IC50 = 1.5 µM and 5.6 µM for Cdk4/D1 and Cdk6/D1, respectively) |
|
| DC20921 |
CDK5 inhibitor 20-223 |
CDK5 inhibitor 20-223 (CP 668863) potent, selective, ATP-competitive CDK2/5 inhibitor with IC50 of 6.0 and 8.8 nM for CDK2/CyclinE and CDK5/p35, with little to no activity against CDK1/4/6/7/9. |
|
| DC12528 |
CDK9 inhibitor HH1
Featured
|
CDK9 inhibitor HH1 is a novel potent, highly selective CDK9 inhibitor.. |
|
| DC20335 |
CDK9-IN-8
Featured
|
CDK9-IN-8 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition. |
|
| DC9478 |
CDK9-IN-1 |
CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection.
|
|
| DC23138 |
CDK-I73
Featured
|
CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM, shows cytotoxicity against a broad CLL samples with mean LD50 of 80 nM. |
|
| DC9390 |
CDK-IN-2
Featured
|
CDK-IN-2 is a potent and sepecific CDK inhibitor. |
|
| DC11393 |
CDM-NAG
Featured
|
CDM-NAG is a useful tool compound to deliver the siRNA. |
|
| DC10948 |
CDN1163
Featured
|
CDN1163 (CDN-1163) is a small molecule, allosteric activator of SERCA2, dose-dependently increases the Vmax of SERCA2 Ca2+-ATPase activity in ER microsomes; increases Ca2+-ATPase activity and significantly enhances Ca2+ uptake into the ER, attenuates H2O2-stimulated cell death in HEK cells; improves glucose homeostasis and metabolic parameters, increases glucose tolerance in ob/ob mice; CDN1163 reduces lipid accumulation and decreases lipogenesis in obese mice livers. |
|
| DC20879 |
CDP-840 |
CDP-840 (CDP840. |
|
| DC20880 |
CDP-840 hydrochloride |
CDP-840 (CDP840. |
|
| DC23463 |
CDPPB
Featured
|
CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively. |
|
| DC22446 |
CE-224535 |
CE-224535 (PF-04905428) is a potent and selective P2X7 receptor antagonist with IC50 of 1.4 nM (inhibition of the release of lL-1b from monocytes stimulated by ATP). |
|
| DC20881 |
CE-245677 |
CE-245677 is a potent, selective, orally active, dual Tie2/Trk kinase inhibitor with IC50 of 4.7 nM, 1 nM for Tie2 and TrkA/B, respectively. |
|
| DC20336 |
CE3F4
Featured
|
CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity. |
|
| DC23912 |
Cecropin B |
Cecropin B is an antimicrobial peptide with MICs(0.5 to 16 ug/ml) against Gramnegative strains. |
|
| DC20987 |
Cedazuridine
Featured
|
Cedazuridine (E7727) is a novel cytidine deaminase inhibitor, and a componet of ASTX727 for treatment of hematologic malignancies.. |
|
| DC3170 |
Cediranib
Featured
|
Cediranib (AZD2171) is a highly potent VEGFR2 inhibitor with IC50 of 0.5 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM. |
|
| DCAPI1386 |
Cefdinir (Omnicef) |
Cefdinir (Omnicef) |
|
| DCAPI1024 |
Cefditoren pivoxil |
Cefditoren pivoxil |
|
