| DC9597 |
Doxapram (hydrochloride hydrate) |
Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
|
|
| DC9664 |
Doxapram
Featured
|
Doxapram inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively. |
|
| DC9061 |
Doxepin HCl |
Doxepin HCl is a tricyclic antidepressant that is marketed worldwide. |
|
| DCAPI1241 |
Doxercalciferol (Hectorol)
Featured
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Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease. |
|
| DC8994 |
Doxifluridine/5-Fluoro-5′-deoxyuridine |
Doxifluridine(Ro 21-9738; 5'-DFUR) is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM. |
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| DC4188 |
Doxorubicin hydrochloride
Featured
|
Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. |
|
| DC9109 |
Doxylamine succinate |
Doxylamine is a first generation antihistamine; can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief. |
|
| DC8383 |
Dp44mT
Featured
|
Dp44mT is a potent iron chelator, which shows selective antitumor activity. |
|
| DC23775 |
DPA-714 |
DPA-714 is a potent, selective ligand for the translocator protein (TSPO) with Ki of 7.0 nM. |
|
| DC20966 |
DPM-1001
Featured
|
DPM-1001 is a potent, selective, orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B with IC50 of 100 nM, also chelates copper, which enhanced its potency as a PTP1B inhibitor. |
|
| DC9949 |
DprE1-IN-2
Featured
|
DprE1-IN-2 is a potent DprE1 inhibitor. |
|
| DC11173 |
DRAinh-A250
Featured
|
DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA), fully and reversibly inhibits SLC26A3-mediated Cl- exchange with HCO3-, I-, and thiocyanate (SCN-) with IC50 of ~0.2 uM. |
|
| DC20366 |
DRAK2-IN-16 |
DRAK2-IN-116 is a potent, selective DRAK2 inhibitor with IC50 of 3 nM, shows weak inhibition for DRAK1 (IC50=51 nM) and no significant activity against DAPK1/2/3 (IC50>1 uM).. |
|
| DC10039 |
DREADD Agonist 21
Featured
|
DREADD agonist 21 is a potent muscarinic hM3Dq DREADD agonist (EC50 = 1.7 nM). Highly selective for hM3Dq DREADDs over endogenous hM3 receptors. |
|
| DC20103 |
D-Ribose(mixture of isomers)
Featured
|
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation |
|
| DC20967 |
DRI-C21045 |
DRI-C21045 is a novel small-molecule inhibitor of CD40-CD40L protein-protein interaction with IC50 of 0.17 uM in cell-based assays. |
|
| DCAPI1457 |
Dronedarone Hydrochloride |
Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium and sodium and is a calcium channel protein inhibitor. |
|
| DCAPI1562 |
Drospirenone
Featured
|
Drospirenone is a synthetic progestogen exhibiting antiandrogenic and antimineralocorticoid activity. |
|
| DC2056 |
Droxidopa (L-DOPS,SM-5688)
Featured
|
Droxidopa (L-DOPS) is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). |
|
| DC8350 |
Droxinostat
Featured
|
Droxinostat is a selective HDAC3, HDAC6 and HDAC8 inhibitor. |
|
| DC10919 |
DRP1 inhibitor 4 |
DRP1 inhibitor 4 is a selective, small molecule inhibitor of the mammalian mitochondrial division dynamin, DRP1 with IC50 of 1.0 uM, shows no activity against OPA1 and DYN1 (IC50>100 uM).. |
|
| DC12598 |
DRV1 (GPR32) agonist C2A |
DRV1 (GPR32) agonist C2A (NCGC00135472) is a synthetic molecule that activate human resolvin D1 receptor DRV1/GPR32 receptor with EC50 of 0.37 uM and 0.05 uM in β-arrestin and cAMP assays, respectively. |
|
| DC20968 |
DS-1040 |
DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
|
| DC20969 |
DS-1040 tosylate |
DS-1040 tosylate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
|
| DC20970 |
DS-1040 tosylate hydrate |
DS-1040 tosylate hydrate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
|
| DC20974 |
DS16570511 |
DS16570511 is a cell-permeable inhibitor of the mitochondrial calcium uniporter (MCU) that inhibits serum-induced mitochondrial Ca2+ influx in HEK293A cells with IC50 of 7 uM. |
|
| DC20975 |
DS-2330
Featured
|
DS-2330 is a phosphorous lowering agent for treating hyperphosphatemia in chronic kidney disease.. |
|
| DC20971 |
DS-2969b |
DS-2969b (DS 11960558) is a novel orally active GyrB inhibitor, inhibits the supercoiling activity of C. difficile DNA gyrase with IC50 of 20 ng/mL. |
|
| DC11726 |
Milademetan
Featured
|
Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest, senescence and apoptosis. |
|
| DC12410 |
8-{1-[(1R,4R)-4-aminocyclohexyl]ethenyl}-5,5-dimethyl-5,6-dihydrobenzo[h]quinazolin-4-amine
Featured
|
DS42450411 (DS 42450411, DS-42450411) is a potent, orally active hepcidin production inhibitor with IC50 of 32 nM. |
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