TC-DAPK-6|cas 315694-89-4|Price|Buy|DC Chemicals

Cas No.:	315694-89-4
Synonyms:	DAPK inhibitor
SMILES:	O=C(OC(/C=C/C1=CC=CC=C1)=N/2)C2=C/C3=CC=CN=C3
Formula:	C₁₇H₁₂N₂O₂
M.Wt:	276.29
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Death-associated protein kinase (DAPK) is a serine/threonine protein kinase implicated in diverse programmed cell death pathways. DAPK is a promising target protein For the treatment of ischemic diseases. TC-DAPK 6 is an oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 ?M ATP); while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 ?M.For the detailed information of TC-DAPK-6, the solubility of TC-DAPK-6 in water, the solubility of TC-DAPK-6 in DMSO, the solubility of TC-DAPK-6 in PBS buffer, the animal experiment (test) of TC-DAPK-6, the cell expriment (test) of TC-DAPK-6, the in vivo, in vitro and clinical trial test of TC-DAPK-6, the EC50, IC50,and Affinity of TC-DAPK-6, Please contact DC Chemicals.

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2018-0101

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