Cas No.: | 2753-30-2 |
Chemical Name: | (1S,3aS,4aR,4bS,5R,6aR,10aR,10bR,12aS)-5-(Acetyloxy)-1-(3-furanyl)-1,5,6,6a,7,10a,10b,11,12,12a,decahydro-4b,7,7,10a,12a,-pentamethyloxireno[c]phenanthro[1,2-d]pyran-3,8(3aH,4bH)-dione |
SMILES: | CC(=O)O[C@H]1[C@@]2(C)[C@]34[C@](CCC2[C@]5(C)C(C(C)(C)C(=O)C=C5)C1)(C)[C@H](C6=COC=C6)OC(=O)[C@H]3O4 |
Formula: | C28H34O7 |
M.Wt: | 482.57 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A natural tetranortriterpenoid compound that inhibits Hsp90 and induce the degradation of Hsp90-dependent client proteins; displays antiproliferative activity in vitro with IC50 of 3.22, 8.84 and 16.8 uM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively; also shows potential antimalarial activity against P. falciparum. |