Cas No.: | 171336-24-6 |
Chemical Name: | RU1968 bis-TFA salt |
Synonyms: | RU1968 bis-TFA salt |
SMILES: | FC(C(=O)O)(F)F.FC(C(=O)O)(F)F.OC1C=CC2=C(C=1)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(C)NCCN(C)C)CC[C@H]21 |
Formula: | C28H40F6N2O5 |
M.Wt: | 598.618029594421 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | RU1968 is a potent, cross-species sperm-specific Ca2+ channel CatSper inhibitor that is selective for CatSper over Slo3; suppresses progesterone- and prostaglandin-induced Ca2+ signals in human sperm (IC50=4 and 3.8 uM), potently abolishes CatSper-mediated Ca2+ signals in mouse, human, and sea urchin sperm. |