Cas No.: | 21963-95-1 |
Chemical Name: | (1R,4bR,5R,6aR,10aR,10bR,12aR)-5-(Acetyloxy)-1-(3-furanyl)-1,5,6,6a,7,10a,10b,11,12,12a-decahydro-4b,7,7,10a,12a-pentamethyl-3H-phenanthro[2,1-c]pyran-3,8(4bH)-dione |
Synonyms: | 14,15-deoxygedunin |
Formula: | C28H34O6 |
M.Wt: | 466.566 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A naturally occurring tetranortriterpenoid that has been found to act as a potent, selective, small-molecule agonist of TrkB with Kd of 1.4 uM; activates TrkB in mouse brain in a BDNF-independent way, prevents the degeneration of vestibular ganglion in BDNF -/- pups, and produces TrkB-dependent neurotrophic and neuroprotective effects in mice and enhances learning processes. |