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CL-82198

  Cat. No.:  DC23189   Featured
Chemical Structure
307002-71-7
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More than 5000 active chemicals with high quality for research!
Field of application
CL-82198 is a selective inhibitor of MMP-13. CL-82198 binds to the entire S1’ pocket of MMP-13, which is the basis for its selectivity towards MMP-13 and the lack of inhibitory activities against other MMPs. CL-82198 is a pharmacologic treatment for preventing osteoarthritis (OA) progression.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 307002-71-7
Chemical Name: CL-82198
Synonyms: CL 82198 hydrochloride;CL-82198;N-(4-morpholin-4-ylbutyl)-1-benzofuran-2-carboxamide,hydrochloride;CL82198;IN1376;N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide;N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxaMidehydrochloride
SMILES: O=C(C1=CC2=CC=CC=C2O1)NCCCCN3CCOCC3
Formula: C17H22N2O3.HCl
M.Wt: 338.82912
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A potent, selective inhibitor of MMP-13 (89% inhibition at 10 ug/mL); displays no activity at MMP-1, MMP-9 and TACE; significantly reduces the migration of LS174 cells by 55% at 10 uM.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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