Diprotin A| cas 90614-48-5

Cas No.:	90614-48-5
Chemical Name:	Diprotin A
Synonyms:	L-Isoleucine,L-isoleucyl-L-prolyl-;DiprotinA;H-Ile-Pro-Ile-OH;ILE-PRO-ILE;DIPEPTIDYLPEPTIDASE IV INHIBITOR I;H-ILE-PRO-ILE-OH H2O;ILE-PRO-ILE H2O;Ile-Pro-Ile-OH;L-Ile-L-Pro-L-Ile-OH;L-Isoleucyl-L-prolyl-L-isoleucine;Diprotin A;Ile-Pro-Ile;L-Isoleucine, N-(1-L-isoleucyl-L-prolyl)- (ZCI);L-Isoleucyl-L-prolyl-L-isoleucine (ACI);3: PN: JP2011182742 SEQID: 3 unclaimed protein;JNTMAZFVYNDPLB-PEDHHIEDSA-N;Dipeptidyl peptidase IV inhibitor;isoleucylprolylisoleucine;BSPBio_003515;SMP1_000085;NCGC00178015-01;(2S,3S)-2-((S)-1-((2S,3S)-2-amino-3-methylpentanoyl)pyrrolidine-5-carboxamido)-3-methylpentanoic acid;BDBM50229666;BCBcMAP01_000164;CHEMBL214381;L-Isoleucine, N-(1-L-isoleucyl-L-prolyl)-;CS-0034521;Spectrum2_001480;CHEBI:93213;BRD-K69032158-001-02-2;IPI;AKOS030210980;SCHEMBL6404766;HY-111174;90614-48-5;Spectrum3_001838;DTXSID80920277;(2S,3S)-2-[[[(2S)-1-[(2S,3S)-2-amino-3-methyl-1-oxopentyl]-2-pyrrolidinyl]-oxomethyl]amino]-3-methylpentanoic acid;MFCD00038707;N-(1-L-Isoleucyl-L-prolyl)-L-isoleucine;N-[Hydroxy(1-isoleucylpyrrolidin-2-yl)methylidene]isoleucine;MS-25221;CCG-38872;l-isoleucyl-l-prolyl-l-isoleucine;Diprotin A (H-L-Ile-L-Pro-L-Ile-OH);isoleucyl-prolyl-isoleucine;Diprotin A (Ile-Pro-Ile);(2S,3S)-2-((S)-1-((2S,3S)-2-Amino-3-methylpentanoyl)pyrrolidine-2-carboxamido)-3-methylpentanoic acid;SPBio_001439;KBio3_003020;diprotin A;Q27164930
SMILES:	C(N1CCC[C@H]1C(=O)N[C@H](C(=O)O)[C@@H](C)CC)(=O)[C@@H](N)[C@@H](C)CC
Formula:	C₁₇H₃₁N₃O₄
M.Wt:	341.445744752884
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Diprotin A is a tripeptide inhibitor of dipeptidyl peptidase 4 (DPP-4; IC50 = 1.1 μg/ml).It inhibits degradation of glucagon-like peptide 1 in culture with insulin-secreting BRIN-BD11 rat pancreatic β-cells when used at a concentration of 25 μM.Diprotin A (5 mg/ml) pre-incubation enhances chemotaxis of murine embryonic stem cells towards stromal cell-derived factor-1 (SDF-1/CXCL12) in vitro.Pre-incubation of CD34+ human umbilical cord blood cells with diprotin A (5 mM) prior to injection increases engraftment in NOD/SCID recipient mice.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC33635	DODAP	DODAP, also known as 1,2-Dioleoyl-3-dimethylammonium-propane, is a cationic lipid. It has been used as a component in liposomes that can be used to encapsulate siRNA, immunostimulatory oligodeoxynucleotides, antisense oligonucleotides, or chemotherapeutic agents for in vitro and in vivo delivery.
DC31074	Isopropyl myristate	Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
DC74557	PREX-in1	PREX-in1 is a specific small-molecule inhibitor of P-Rex1 and P-Rex2 Rac-GEF activity with IC50 of 4.5 uM (P-Rex1 DHPH Rac-GEF activity) in liposome-based GEF assay, inhibits P-Rex1 and P-Rex2 through their catalytic DH domain.
DC74555	GYS32661	GYS32661 (GYS 32661) is a potent Rac inhibitor capable of inhibiting both Rac1 and Rac1b, inhibited activated Rac1 with IC50 of 1.18 uM in in vitro pull-down assays.
DC74539	L557-0155	L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.
DC74528	K284	K284 is a selective small molecule inhibitor of chitinase 3 like1 (CHI3L1) with strong binding affinity (Kd=-9.7 kcal·mol-1), inhibits lung metastasis by blocking IL-13Rα2-mediated JNK-AP-1 signals.
DC74225	YB-537	YB-537 (YB537) is a potent, highly specific quinone reductase 2 (QR2) inhibitor with IC50 of 3 nM, shows no activity against QR1 (IC50>10 uM).
DC74218	UT-59	UT-59 is a specific inhibitor of cholesterol-sensing membrane protein Scap, binds to Scap's cholesterol-binding site, blocks SREBP activation and inhibits lipid synthesis.
DC74205	Tryptolinamide	Tryptolinamide (TLAM) is a small-molecule compound that activates mitochondrial respiration in cybrids generated from patient-derived mitochondria and fibroblasts from patient-derived iPSCs, inhibits phosphofructokinase-1 (PFK1) with an ATP-uncompetitive
DC74198	TMX-4102	TMX-4102 (TMX4102) is a highly potent, selective PIP4K2C binder with KD of 0.45 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM).