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H-7 inhibitor

  Cat. No.:  DC50088   Featured
Chemical Structure
84477-87-2
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More than 5000 active chemicals with high quality for research!
Field of application
H-7 is a specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 84477-87-2
Chemical Name: Protein kinase inhibitor H-7
Synonyms: Isoquinoline,5-[(2-methyl-1-piperazinyl)sulfonyl]-;1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE;5-[(2-methyl-1-piperazinyl)sulfonyl]Isoquinoline;H-7;H-7 dihydrochloride,(±)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazinedihydrochloride;(±)-1-(5-Isoquinolinesulphonyl)-2-Methylpiperazinedihydrochloride;H-7 dihydrochloride;H-72HCl;1-(5-Isoquinolinesulfonyl)-2-methylpiperazine;Isoquinoline-5-sulfonic 2-methyl-1-piperazide;Protein kinase inhibitor H-7
SMILES: CC1CNCCN1S(C1C=CC=C2C=1C=CN=C2)(=O)=O
Formula: C14H17N3O2S
M.Wt: 291.36868
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC50088 H-7 inhibitor H-7 is a specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
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DC28223 Bisindolylmaleimide IV Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM). Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM.
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