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Higenamine hydrochloride

  Cat. No.:  DCZ-139   Featured
Chemical Structure
11041-94-4
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More than 5000 active chemicals with high quality for research!
Field of application
Higenamine hydrochloride is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 11041-94-4
Chemical Name: Higenamine hydrochloride
Synonyms: 6,7-Dihydroxy-1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline Hydrochloride;Demethylcoclaurine hydrochloride;6,7-Isoquinolinediol,1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-, hydrochloride (1:1);Demethyl;Higenamine HCL;HigenaMine hydrochloride;pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-6(7H)-one;(±)-Norcoclaurine hydrochloride;(±)-Demethylcoclaurine hydrochloride;(±)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-Isoquinolinediol hydrochloride;(±)-Demethylcoclaurine;(±)-O-Demethylcoclaurine hydrochloride;(RS)-Norcoclaurine hydrochloride;1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-isoquinolinediol hydrochloride;dl-Demethylcoclaurine hydrochloride;1,2,3,4-Tetrahydro-1-((4-hydroxyphenyl)methyl)-6,7-isoquinolinediol hydrochloride;norcoclaurine hcl;6,7-dihydroxy-1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline;1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride;6,7-DIHYDROXY-1-(4-HYDROXYBENZYL)-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHL+;(+-)-Demethylcoclaurine hydrochloride;(+-)-1,2,3,4-Tetrahydro-1-((4-hydroxyphenyl)methyl)-6,7-isoquinolinediol hydrochloride;6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-((4-hydroxyph;Higenamine (hydrochloride);6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-((4-hydroxyphenyl)methyl)-, hydrochloride, (+-)-;6,7-Isoqui;norcoclaurine HCl;J-503750;Higenamine HCl;FT-0696741;1-[(4-Hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol--hydrogen chloride (1/1);(+/-)-DEMETHYLCOCLAURINE HYDROCHLORIDE;AKOS025287070;1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydro-6,7-isoquinolinediol hydrochloride;6,7-dihydroxy-1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride;XH163199;11041-94-4;11041-94-4 (HCl);(+/-)-Higenamine HCl - natural;1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride;1ST40288A;Higenamine?Hydrochloride;(+/-)-Higenamine HCl - synthetic;AS-10415;Q27286703;PQ432PID6E;6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-, hydrochloride (1:1);MFCD01717353;DTXSID10911673;DEMETHYLCOCLAURINE HYDROCHLORIDE, (+/-)-;1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride;1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrochloride;6 pound not7-Dihydroxy-1-(4-Hydroxybenzyl)-1 pound not2 pound not3 pound not4-tetrahydroisoquinoline Hydrochloride;AC-26395;CS-0016803;Demethylcoclaurine HCl;BCP07397;6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-1-((4-HYDROXYPHENYL)METHYL)-, HYDROCHLORIDE (1:1);HY-N2037A;CCG-267555;UNII-PQ432PID6E;SY029900;6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-1-((4-HYDROXYPHENYL)METHYL)-, HYDROCHLORIDE, (+/-)-;6,7-Dihydroxy-1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline HCl;Z2940609369;s3960;_x000D_67-Dihydroxy-1-(4-Hydroxybenzyl)-1234-tetrahydroisoquinoline Hydrochloride;EN300-822191;Norcoclaurine hydrochloride;1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydro-6,7-isoquinolinedi...
SMILES: Cl[H].O([H])C1=C(C([H])=C2C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])C3C([H])=C([H])C(=C([H])C=3[H])O[H])C2=C1[H])O[H]
Formula: C16H18ClNO3
M.Wt: 307.7720
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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