| DC72381 |
α-Demethylnaproxen
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α-Demethylnaproxen is the major metabolite of Nabumetone, Nabumetone is an orally active COX-2 inhibitor with anti-inflammatory activity. |
| DC72057 |
Ilaprazole sulfone
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Ilaprazole sulfone is the major metabolite of Ilaprazole, is predominantly catalysed by CYP3A4/5. Ilaprazole (IY-81149) is an orally active proton pump inhibitor.
|
| DC71390 |
Ribavirin carboxylic acid
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Ribavirin carboxylic acid (TR-COOH) is a metabolite of ribavirin, ribavirin has strong antiviral activity. |
| DC49764 |
3-Amino-2-oxazolidinone-d4
|
3-Amino-2-oxazolidinone-d4 is a deuterium labeled 3-Amino-2-oxazolidinone. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone. 3-Amino-2-oxazolidinone is always be detected as an indicator of furazolidone residues.
|
| DC46299 |
4'-Hydroxy diclofenac D4
|
4'-Hydroxy diclofenac D4 is the deuterium labeled 4'-Hydroxy diclofenac. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties. |
| DC42345 |
Dasatinib metabolite M6
|
Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib. Dasatinib is a potent and orally active dual Bcr-Abl and Src family tyrosine kinase.
|
| DC42073 |
(E)-10-Hydroxynortriptyline
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(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression.
|
| DC41481 |
Ferulic acid acyl-β-D-glucoside
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Ferulic acid acyl-β-D-glucoside is a metabolite of Ferulic Acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
|
| DC41289 |
N-Desmethyl imatinib mesylate
|
N-Desmethyl imatinib mesylate (Norimatinib mesylate) is a metabolite of Imatinib. Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR.
|
| DC41188 |
(S)-(+)-O-Desmethyl Venlafaxine D6
|
(S)-(+)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (S)-(+)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.
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