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Cat. No. Product Name Field of Application Chemical Structure
DC10460 BT-11 Featured BT-11 is an orally active and selective LANCL2 modulator.
DC10164 BTB-1 Featured BTB-1 is a small molecule inhibitor of the mitotic motor protein Kif18A.
DC20199 BTK inhibitor 1;Compound 27 Featured BTK inhibitor 1 (Compound 27)
DC23413 BTRX335140 Featured BTRX-335140 (CYM-53093, BTRX335140, CYM53093) is a potent, selective, orally active κ opioid receptor (KOR) antagonist with IC50 of 0.8 nM.
DC12456 BTT-266 Featured BTT-266 (BTT266) is a voltage-gated CaV2.2 calcium channel inhibitor that disrupts the CaVα·CaVβ3 protein-protein interaction, directly binds to CaVβ3 with Kd of 3.6 uM.
DC23703 BTYNB Featured BTYNB is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA with IC50 of 5 uM.
DC9704 Unii-G55ZH52P57 Featured BTZ043 is a inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), It can display nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro.
DCAPI1392 BTZ043 racemate Featured BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.
DC22041 BTZO-1 Featured BTZO-1 is a cardioprotective agent and Macrophage migration inhibitory factor (MIF) activator, binds to MIF with Kd of 68.6 nM, regulates ARE-mediated gene expression.
DC6501 Bufalin Featured Bufalin inhibits steroid receptor coactivator 1 (SRC-1) and SRC-3 at doses as low as 5 nM, promotes the degradation of SRC-3 protein, and inhibits cancer cell growth both in vitro and in vivo.
DCAPI1140 Bumetanide Featured Bumetanide
DC11381 Butabindide (oxalate) Featured Butabindide is a potent inhibitor of cholecystokinin-inactivating peptidase/tripeptidyl peptidase 2 (CCK-inactivating peptidase/TPP-2; Ki = 7 nM).1 It is selective for CCK-inactivating peptidase/TPP-2 over a panel of serine proteases (Kis = >1 μM) as well as CCK receptors (Kis = >0.1 mM).
DC10693 O-Butyryl timolol Featured Butyryltimolol is a lipophilic ester prodrug of timolol, a beta adrenergic blocer with antihypertensive and hemodynamic properties.
DC7563 BV6 Featured BV6 induced apoptotic and necrotic cell death in monocytes while T-cells, dendritic cells and macrophages were largely protected against BV6-induced cell death.
DC8089 BVT 2733(BVT.2733) Featured BVT 2733 is a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor,protecting osteoblasts against endogenous glucocorticoid induced dysfunction.
DC8278 BVT-14225 Featured BVT 14225 is a new selective 11b-HSD1 inhibitor, it belongs to a class of arylsulfonamidothiazoles with in vitro and in vivo antidiabetic effects
DC21685 BVT-948 Featured BVT-948 (SPS8I-3) is a noncompetitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) with IC50 of 0.09-1.7 uM. Results show that the effect of BVT948 (BVT.948) is to strengthen the insulin signal and has no effects on the duration of th
DC12041 BW-A 78U Featured BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM.
DC7675 BX-471(ZK 811752) Featured BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1); exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
DC8808 BX-513 hydrochloride Featured BX-513 hydrochloride inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM).
DC8062 BX517 Featured BX517 is a novel phosphoinositide-dependent kinase-1 (PDK1) inhibitor.
DC7092 BX795 Featured BX795 is a potent and selective dual inhibitor of TBK1/PDK1 with IC50s of 2 nM/6 nM respectively; > 50 fold selectivity over PKA, PKC, c-Kit, GSK3β etc.
DC7093 BX912 Featured BX-912 is a selective inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1) with IC50 of 12 nM; >10 fold selectivity over PKA, PKC, C-Kit, EGFR etc.
DC11219 BXI-72 Featured BXI-72 (NSC334072) is a potent, selective small molecule Bcl-XL inhibitor that targets the BH3 domain of Bcl-XL (Kd=0.9 nM).
DC7094 Alpelisib(BYL-719) Featured BYL719 is a potent and selective PI3Kα inhibitor with IC50 of 5 nM, ;liitle or no effect on PI3Kβ/γ/δ.
DC26049 Bz-IEGR-pNA (acetate) Featured Bz-IEGR-pNA is a colorimetric substrate for Factor Xa.
DC11453 Bz-Nle-Lys-Arg-Arg-AMC Featured Bz-Nle-Lys-Arg-Arg-AMC is a substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease.
DC10864 C188-9 Featured C188-9 is a potent inhibitor of STAT3 that binds to STAT3 with high affinity (KD=4.7±0.4 nM). C188-9 is well tolerated in mice, shows good oral bioavailability, and is concentrated in tumors.
DC10937 C25-140 Featured C25-140 is a specific, first-in-class small molecule inhibitor of the TRAF6-Ubc13 interaction, binds TRAF6, inhibits TRAF6-Ubc13 interaction and TRAF6 activity.
DC10276 C29 Featured C29 is a potential TLR2 inhibitor.

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