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Cat. No. Product name CAS No.
DC65458 Denintuzumab mafodotin Featured

Depatuxizumab Mafodotin (Depatux-M, ABT-414) is an antibody-drug conjugate consisting of an EGFR IGg1 monoclonal antibody conjugated to the tubulin inhibitor monomethyl auristatin F via a stable maleimidocaproyl link. Depatuxizumab Mafodotin is used in the treatment of recurrent EGFR-amplified Glioblastoma (GBM).

1585973-65-4
DC65459 Enapotamab vedotin Featured

Enapotamab vedotin (EnaV, HuMAX-AXL-ADC) is an AXL-specific human IgG1 antibody conjugated to the microtubule disrupting agent monomethyl auristatin E (MMAE) through a protease cleavable valine-citrulline (vc) linker.

1912424-97-5
DC65460 Zilovertamab vedotin Featured

Zilovertamab vedotin (VLS-101, MK-2140) is an antibody-drug conjugate (ADC) composed of a humanised monoclonal antibody targeting ROR1 and the anti-mitotic cytotoxic agent monomethyl auristatin E (MMAE). It has potential for the treatment of lymphoid malignancies.

2376463-48-6
A274 Patritumab deruxtecan Featured

Patritumab deruxtecan (HER3-DXd) is an antibody-drug conjugate (ADC) consisting of a fully human anti-HER3 IgG1 monoclonal antibody Patritumab (HY-P99275) attached to a topoisomerase I inhibitor payload via a tetrapeptide-based cleavable linker. Patritumab deruxtecan shows anticancer activity[1].

2227102-46-5
DC65462 Cantuzumab mertansine Featured

Cantuzumab mertansine (SB-408075; huC242-DM1), an ADC, is an immunoconjugate of the potent maytansine derivative (DM1; HY-19792) and the humanized monoclonal antibody (huC242) directed to CanAg. Cantuzumab mertansine has cytotoxic toward colon cancer cells and has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts[1][2].

400010-39-1
DC65463 Clivatuzumab-MMAE Featured

Clivatuzumab-MMAE is an antibody-drug conjugate (ADC) composed of a humanized anti-mucin (MUC1) monoclonal antibody and a anti-mitotic cytotoxic agent monomethyl auristatin (MMAE).

DC65464 Farletuzumab-MMAE Featured

Farletuzumab-MMAE is an antibody-drug conjugate (ADC) composed of humanized anti-human folate receptor-alpha (FRα) and the cytotoxic agent monomethyl auristatin (MMAE) via a MC-Vc linker. It has a potent antitumor activity.

DC65465 L-Ascorbic Acid Phospate Magnesium Salt Hydrate Featured

L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[1][2][3].

1713265-25-8
DC65466 Phenylthiourea Featured

1-PHENYL-2-THIOUREA(N-Phenylthiourea, PTU, Phenylthiocarbamide) is an inhibitor of tyrosinase (Tyr). 1-PHENYL-2-THIOUREA blocks pigmentation and improves optical transparency in zebrafish (Danio rerio) embryo.

103-85-5
DC65467 Kojic acid dipalmitate Featured

Kojic acid dipalmitate (Kojic dipalmitate) is a derivative of Kojic acid (HY-W050154), a fungal metabolite that can be produced by species of Aspergillus, Acetobacter and Penicillium. Kojic acid dipalmitate is a slow and reversible competitive inhibitor of tyrosinase. Kojic acid dipalmitate can be used for skin‐lightening agent research[1].

79725-98-7
DC65468 Influenza Hemagglutinin (HA) Peptide Featured

HA Peptide (HA tag) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). It is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry.

92000-76-5
DC60483 LIS10W Featured

LIS10W is a sugar-alcohol-derived ionizable lipid with L-sorbitol as the precursor. CD40L-LIS10W in the CATCH (CD40L-LIS10W+CD40-BDMCs) treatment simultaneously induces ICD and CD40L expressions in tumoural tissues, which enables to activate both endogenous DCs and adoptively transferred CD40-BMDCs.

DC65469 Penicillin, streptomycin Featured

Penicillin-Streptomycin is used to prevent microbial contamination of cell culture during long-term in vitro cell culture maintenance.

8025-06-7
DC65470 Belantamab Mafodotin Featured

Belantamab mafodotin (GSK2857916) is a humanized, afucosylated, anti-B-cell maturation antigen (BCMA) monoclonal antibody-drug conjugate (ADC) conjugated to MMAF (HY-15579) via a maleimidocaproyl linker (McMMAF, HY-15578). Belantamab mafodotin shows anti-myeloma activity[1][2].

2050232-20-5
A152 Codrituzumab-MMAE Featured

Codrituzumab-MMAE, is an antibody-drug conjugate composed of a anti-GPC3 monoclonal antibody and a cytotoxic tubulin polymerase inhibitor conjugated through MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) type linker.

DC65472 Pifithrin-β Featured

Pifithrin-β (PFT β hydrobromide; Cyclic Pifithrin-α hydrobromide) is a potent inhibitor of p53 with an IC50 of 23 μM and is regarded as a lead compound for cancer and neurodegenerative disease therapy.

60477-34-1
DC65473 Mps1-IN-6 Featured

Mps1-IN-6 is a potent Mps1 inhibitor with an IC50 value of 2.596 nM. Mps1-IN-6 shows antiproliferative activity. Mps1-IN-6 shows antitumor activity.

2489220-49-5
DC65474 TMRE Featured

TMRE is a mitochondria specific dye (λex=550 nm, λem=575 nm).

115532-52-0
DC65475 JKE-1674 Featured

JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor. JKE-1674 kills cells in a manner that is equipotent to ML210 and is completely rescued by ferroptosis inhibitors[1].

2421119-60-8
DC65476 Serclutamab talirine Featured

Serclutamab Talirine (ABBV-321), is an antibody-drug conjugate (ADC) composed of an humanized immunoglobulin G1 anti-EGFR monoclonal antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a maleimidocaproyl-valine-alanine linker. Serclutamab Talirine has the potential for use in advanced solid tumors associated with overexpression of the epidermal growth factor receptor (EGFR) or its ligands.

2140174-56-5
DC65477 Laprituximab emtansine Featured

Laprituximab emtansine (IMGN-289) is an immunotoxin targeting HER1. Laprituximab emtansine is an EGFR antibody-drug conjugate (ADC) consisting of the J2898A antibody, DM1 (anti-microtubule agent) and the SMCC thioether linker. Laprituximab emtansine can be used for cancer research[1][2][3].

1622327-37-0
DC65478 Cetuximab-MMAE Featured

Cetuximab-MMAE is an antibody-drug conjugate composed of a anti-EGFR monoclonal antibody and a cytotoxic tubulin polymerase inhibitor conjugated through MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) type linker.

DC65479 Necitumumab (anti-EGFR) Featured

Necitumumab (anti-EGFR) is an epidermal growth factor receptor (EGFR) antagonist that can be used in combination with gemcitabine and cisplatin for the first-line treatment of patients with metastatic squamous non-small cell lung cancer.

906805-06-9
DC65480 TPH104m Featured

DC65481 Eeyarestatin I Featured

Eeyarestatin I is a potent inhibitor of endoplasmic reticulum-associated protein degradation (ERAD). Eeyarestatin I also inhibits Sec61 translocon.

412960-54-4
DC65482 Amyloid beta-peptide(25-35) Featured

β-Amyloid (25-35) (Amyloid beta-peptide (25-35), Aβ25-35, β-Amyloid peptide (25-35)) , a sequence GSNKGAIIGLM, is a highly toxic synthetic derivative of Amyloid beta-peptide (Aβ-peptides) which forms fibrillary aggregates. β-Amyloid (25-35) is involved in the pathogenesis of Alzheimer's disease.

131602-53-4
DC65483 SI-2 (hydrochloride) Featured

SI-2 hydrochloride (EPH 116 hydrochloride) is a highly promising SRC-3 SMI: SRC-3 inhibitor (PPI), with IC50 values of 3-20 nM for breast cancer cell death. SI-2 hydrochloride (EPH 116 hydrochloride) has a much improved toxicity and pharmacokinetic profile, with acceptable oral availability[1].

1992052-49-9
DC65484 WAY-639889 Featured

WAY-639889 is a bioactive compound relative to neuropeptide Y-5.

432506-24-6
DC65486 ZW290 Featured

ZW290 is a compound to activate brown adipose tissue (BAT) thermogenic function. ZW290 increases the expression of uncoupling Protein 1 (UCP1) protein and inhibits ATP synthesis in BAT.

2411852-67-8
DC65485 CP-226269 Featured

CP 226269 is a potent dopamine D4 receptor agonist that induces calcium flux with EC50 of 32.0 nM. CP 226269 can be used in the research of schizophrenia and other related diseases.

220941-93-5
DC65487 SRD5A1-IN-1 Featured

SRD5A1-IN-1 (Compound 4) is a competitive and covalent steroid 5α-reductase type 1 (SRD5A1) inhibitor with an IC50 of 1.44 µM. SRD5A1-IN-1 modulates SRD5A1 function, leading to a lower level of dihydrotestosterone (DHT) production and SRD5A1 protein suppression[1].

2279077-93-7
DC65489 CRCD2 Featured

CRCD2 is an NT5C2 (cytosolic 5’ nucleotidase II) inhibitor with a kd of 70.9 μM. It enhances the cytotoxic effects of 6-MP and effectively reverses thiopurine resistance mediated by genetic and non-genetic mechanisms of NT5C2 activation in ALL.

DC65490 Colestipol hydrochloride Featured

Colestipol hydrochloride, a salt form of Colestipol, is a high-molecular-weight, insoluble, granular copolymer of tetraethylenepentamine and epichlorohydrin. It functions as an anion-exchange and resin-sequestering agent. Colestipol hydrochloride reduces cholesterol levels without affecting triglycerides.

37296-80-3
DC65491 TMRM Perchlorate Featured

TMRM Perchlorate is a cell-permeant cationic lipophilic red fluorescent dye (λex=530 nm, λem=592 nm).

115532-50-8
DC65492 Copper sulfate Featured

Cupric sulfate (Copper(II) sulfate) is a salt formed by treating cupric oxide with sulfuric acid. Cupric sulfate is a lewis acid catalyst commonly used to promote acid-catalyzed organic transformations.

7758-98-7
DC65493 SIRT5 inhibitor 5 Featured

SIRT5 inhibitor 5 is a potent SIRT5 inhibitor with an IC50 value of 0.21 µM.

DC65494 HDAC-IN-57 Featured

HDAC-IN-57 is an orally active inhibitor of histone deacetylases (HDAC), with IC50s of 2.07 nM, 4.71 nM, 2.4 nM and 107 nM for HDAC1, HDAC2, HDAC6, HDAC8, respectively. HDAC-IN-57 can inhibits LSD1, with IC50 of 1.34 μΜ. HDAC-IN-57 induces apoptosis, and has anti-tumor activity[1].

2716217-79-5
DC65495 PYZ18 Featured

PYZ18 is a selective COX-2 inhibitor with an IC50 of 7.07 μM. PYZ18 is the best lead compound for COX-2 inhibitors. PYZ18 has anti-inflammatory and other biological properties[1].

1447578-01-9
DC65496 Gcase activator 2 Featured

Gcase activator 2 (compound 14), a pyrrolo[2,3-b]pyrazine, is alos a β-Glucocerebrosidase (GCase) activator (EC50=3.8 μM). Gcase activator 2 induces GCase dimerizatio (both K-type and V-type). And Gcase activator 2 has low metabolic clearance in human and mouse[1].

2759897-35-1
DC65497 CYP4Z1-IN-1 Featured

CYP4Z1-IN-1 (compound 7c) is a potent CYP4Z1 inhibitor, with an IC50 of 41.8 nM. CYP4Z1-IN-1 decreases the expression of breast CSCs stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo[1].

2760611-38-7
DC65498 hCAII-IN-9 Featured

hCAII-IN-9 is a potent carbonic anhydrase inhibitor

2878477-18-8
DC65499 hCAII-IN-8 Featured

hCAII-IN-8, an amide, is a highly selective carbonic anhydrase (CA) inhibitor with an IC50 value of 0.18 μM against hCA II[1].

952306-80-8
DC65500 GW6340 Featured

GW6340 is an intestinal-specific LXR agonist.

405910-78-3
DC65501 GFP16 Featured

GFP16 is a low affinity antiprion compound.

749212-56-4
DC65502 BI-2865 Featured

BI-2865 is a none-covalent pan-KRAS Inhibitor. BI-2865 blocked nucleotide exchange to prevent the activation of wild-type KRAS and a broad range of KRAS mutants, including G12A/C/D/F/V/S, G13C/D, V14I, L19F, Q22K, D33E, Q61H, K117N and A146V/T. Inhibition of downstream signalling and proliferation was restricted to cancer cells harbouring mutant KRAS, and drug treatment suppressed KRAS mutant tumour growth in mice, without having a detrimental effect on animal weight.

2937327-93-8
DC65503 KIF18A-IN-3 Featured

KIF18A-IN-3 is a potent KIF18A inhibitor (IC50=61 nM). KIF18A-IN-3 causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues. KIF18A-IN-3 can be used for researching cancer[1].

2600577-49-7
DC65504 Skp2 inhibitor 1 Featured

Skp2 inhibitor 1 (compound 14i) is a potent and selective Skp2 inhibitor

2760612-63-1
DC65505 PRMT6-IN-3 Featured

PRMT6-IN-3 (compound 25) is a selective PRMT6 inhibitor

2890765-10-1
DC65506 PARP10-IN-2 Featured

PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 3.64 μM for human PARP10. PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC50s of 27 μM and 11 μM for human PARP2 and human PARP15, respectively[1].

1042780-52-8
DC65507 PHGDH-IN-3 Featured

PHGDH-IN-3 is an orally active phosphoglycerate dehydrogenase (PHGDH) inhibitor. PHGDH-IN-3 inhibits PHGDH with an IC50 value of 2.8 μM. PHGDH-IN-3 can be used for the research of cancer[1].

2893778-31-7
DC65508 MyD88-IN-1 Featured

MyD88-IN-1 is a potent MyD88 inhibitor.

2911609-80-6
DC65509 TNF-α-IN-9 Featured

TNF-α-IN-9 (compound 48) is a analog of NDM-1 inhibitor-3

2054199-25-4
DC65510 Antibacterial agent 132 Featured

Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258)

DC65511 Antibacterial agent 133 Featured

Antibacterial agent 133 (4l) is an antimicrobial agent

DC65512 WDR5-IN-6 Featured

WDR5-IN-6 is a WDR5 inhibitor.

326901-92-2
DC65513 HYNIC-FAPI-04 Featured

HYNIC-FAPI-04 is a useful ligand for making [99mTc]Tc-HYNIC-FAPI-04. In vitro experiments, the results indicated that [99mTc]Tc-HYNIC-FAPI-04 showed binding properties, and inhibited the migration of tumor cells. The [99mTc]Tc-HYNIC-FAPI will be a promising SPECT/CT imaging probe.

DC65514 NOTA-FAPI-46 Featured

NOTA-FAPI-46 is an analogue of FAPI-46 (MedKoo Cat#207189). NOTA-FAPI-46 is useful in the diagnosis or treatment of a disease characterized by overexpression of fibroblast activation protein (FAP). NOTA-FAPI-46 can be used as a PET tracer for detection of diseases or disorders related to fibroblast activation protein.

DC65515 HYNIC-PSMA Featured

HYNIC-PSMA is a PSMA based ligand, which can bind radio-active metal ion and used as a tumor-imaging agent in prostate cancer. 99mTc-HYNIC-PSMA is a novel technetium-99m-labeled small-molecule inhibitor of prostate-specific membrane antigen (PSMA) for detection of prostate cancer. 99mTc-HYNIC-PSMA showed high tracer uptake (with a tumor-to-background ratio of 9.42 ± 2.62) in the malignant lesions of PCa patients, making it a promising radiopharmaceutical imaging method for site-specific management of PCa.

DC65516 PSMA-BCH Featured

PSMA-BCH also known as NOTA-PSMA, is a PSMA- NOTA-conjugated precursor. 68Ga-PSMA-BCH can be used for prostate cancer imaging. Al18F-PSMA-BCH can be used for prostate cancer imaging as a novel 18F PET radiotracer. 64Cu-PSMA-BCH is a new radiotracer for delayed PET imaging of prostate cancer. 64Cu-PSMA-BCH was PSMA specific and showed high stability in vivo with lower uptake in liver than 64Cu-PSMA-617. Biodistribution in mice and PCa patients showed similar profile compared with other PSMA ligands and it was safe with moderate effective dosimetry.

1703768-73-3
DC65517 PSMA-I&T Featured

PSMA-I&T is a PSMA-based radioligand. [177Lu]Lu-PSMA I&T can be uused for potential treatment of metastatic castration-resistant prostate cancer. 67 Ga-PSMA I&T can be used for Radioguided Surgery of Lymph Node Metastases With Biochemical Recurrence of Prostate Cancer

2192281-54-0
DC89101 C12-4 (C12-494,Lipid A-4) Featured

C12-4 (C12-494,Lipid A-4) is a branched-chain ionizable cationic lipidoid that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA. LNPs containing lipid A4 and encapsulating an mRNA reporter accumulate in the uterus, placenta, and ovaries, as well as to the spleen and liver, in pregnant mouse dams unlike LNPs containing the branched-chain ionizable cationic lipidoid C12-200, which primarily accumulate in the liver. Intravenous administration of LNPs containing lipid A4 and encapsulating mRNA encoding VEGF increase placental VEGFR1 levels and mean fetal blood vessel area without inducing liver damage in pregnant mouse dams.

2639634-71-0
DC60484 Clovibactin Featured

Clovibactin is an antibiotic isolated from uncultured soil bacteria. Clovibactin efficiently kills drug-resistant Gram-positive bacterial pathogens without detectable resistance. Clovibactin blocks cell wall synthesis by targeting pyrophosphate of multiple essential peptidoglycan precursors.

2247194-77-8
DC65518 STC15 Featured

Discovery of STC15, an oally bivilble, highly setive METTL3 inibior for the treatment of AML and solid tumours: The fist molecule sifily trgeting an RNA mtytasferase enzyme to enter dinical development

2648257-56-9
DC65519 TNG462 Featured

Discovery of TNG462, a highly potent and selective MTA-cooperative PRMT5 inhibitor that is synthetic lethal for MTAP deleted cancers

2760483-96-1
DC65520 TNG908 Featured

TNG908 is a MTAP-cooperative PRMT5 inhibitor that can pass through the blood-brain barrier. TNG908 is 15 times more selective for MTAP null cell lines than MTAPWT cell lines, and can be used in cancer research.

2760481-53-4
DC65521 PTC-258 2HCl Featured

PTC-258 2HCl is a specific and orally active splicing modulator of Elongator complex protein 1 gene (ELP1). PTC258 increases the expression of ELP1 in vitro and in vivo. PTC258 is well tolerated in mouse model.

2476724-75-9
DC65522 Nico-52 Featured

DC65523 JNT-517 Featured

JNT-517 is a small-molecule inhibitor of the phenylalanine transporter SLC6A19 that has the potential to be a first-in-class oral therapy used to treat any person with PKU, regardless of age or genotype. JNT-517 acts at a novel, cryptic allosteric site to block kidney reabsorption of Phe and offers a promising new approach to reduce blood Phe levels. The FDA has granted JNT-517 Rare Pediatric Disease Designation.

2837993-05-0
DC65524 CHK-336 Featured

CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50<1 nM) that inhibits lactate production in mouse hepatocytes. CHK-336 can be used in the study of hyperoxaluria.

2743436-86-2
DC65525 Resigratinib (KIN-3248) Featured

Activity of KIN-3248, a next-generation pan-FGFR inhibitor, against acquired FGFR-gatekeeper and molecular-brake drug resistance mutations

2750709-91-0
DC72906 BCPA Featured

BCPA is a Pin1 regulator without cytotoxicity. BCPA attenuates the reduction of Pin1 protein to inhibit receptor activator of RANKL-induced osteoclastogenesis. BCPA regulates osteoclast activation, used to osteoporosis research.

547731-67-9
DC72911 CHBO4 Featured

CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research.

98991-32-3
DC72912 IK-930 Featured

IK930 (compound I-32) is a potent and orally active TEAD inhibitor with an EC50 value of <0.1 µM.

2563892-44-2
DC65529 n10-methylfolic acid Featured

Methopterin has the activation and bone resorption function of murine osteoclasts.

2410-93-7
DC65530 niacinamide ascorbate Featured

Nicotinamide ascorbate is a bioactive chemical.

1987-71-9
DC60485 IAJD93 Featured

IAJD93(IAJD-93) is a pentaerythritol-based one-component ionizable amphiphilic Janus Dendrimer (IAJD), delivery systems for mRNA delivery.

DC60486 IAJD 288 Featured

IAJD 288(IAJD-288) is a pentaerythritol-based one-component ionizable amphiphilic Janus Dendrimer (IAJD), delivery systems for mRNA delivery.

DC60487 IAJD249 Featured

IAJD249(IAJD-249) is a pentaerythritol-based one-component ionizable amphiphilic Janus Dendrimer (IAJD), delivery systems for mRNA delivery.

DC65531 Anticancer agent 118 Featured

Anticancer agent 118, a N‑acylated ciprofloxacin derivative, has anti-bacterial and anticancer activities.

864443-43-6
DC65532 MtUng-IN-1 Featured

MtUng-IN-1 (Compound 18a) is a Uracil DNA glycosylase of Mycobacterium (MtUng) inhibitor (IC50: 300 μM). MtUng-IN-1 can be used for research of cancers and infectious diseases.

359826-99-6
DC60488 CL1H6 Featured

CL1H6 is an ionizable lipid and CL1H6-LNP is capable of efficiently introducing both siRNA and mRNA into NK-92 cells.

2256087-63-3
DC60489 LIPID 331 Featured

Lipid 331 is a biodegradable cyclic ionizable lipid. LNPs containing Lipid 331 result in robust transfection in the nasal and lung tissues of mice and efficient transfection of lung epithelial cells and lung-resident APCs. Lipid 331 is a promising candidate for mRNA vaccine delivery, offering the potential for further enhancing the potency of mRNA vaccines.

DC65560 GalNAc-L96 free base Featured

GalNAc-L96 free base, the G-rich oligonucleotides carrying the longer GalNAc linker that can be used for delivery of nucleic acid drugs.

1159408-61-3
DC65559 GalNAc-L96 Phosphoramidite Featured

DC65561 GalNac-L96 analog Featured

GalNac-L96 analog is an analog of GalNac-L96 used for siRNA delivery.

1159408-72-6
DC65562 GalNAc-NAG-25 Phosphoramidite Featured

DC65563 GalNAc-L96-CPG Featured

DC65564 GalNAc-L96-PS Featured

DC65565 GalNac-L96 Featured

GalNac-L96, the G-rich oligonucleotides carrying the longer GalNAc linker that can be used for delivery of nucleic acid drugs[1].

1159408-62-4
DC89083 Pacritinib citrate Featured

Pacritinib Citrate is the citrate salt form of pacritinib, an orally bioavailable inhibitor of Janus kinase 2 (JAK2).

1228923-42-9
DC65567 ABBV-CLS-484 Featured

Osunprotafib (ABBV-CLS-484) is a potent PTPN1 and PTPN2 inhibitor with subnanomolar activity. Osunprotafib has antitumor activity, enhances the immune response and increases the sensitivity of tumors to immune-mediated killing.

2489404-97-7
DC60490 icFSP1 Featured

icFSP1 is a compound class of 3-phenylquinazolinones. icFSP1, unlike iFSP1, is the first described on-target FSP1 inhibitor, does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition.

1115910-36-5
DC65568 C14-494 Core (Lipid Core 494) Featured

C14-4 Core (Core 4) is the core structure of C14-4.

2344685-60-3
DC65569 Eg5-IN-1 Featured

Eg5-IN-1 (compound 6c) is a potent kinesin family motor protein (Eg5) inhibitor

DC65570 Tubulin inhibitor 35 Featured

Tubulin inhibitor 35 (compound 6b) is a dual inhibitor of topoisomerase I and tubulin polymerization.

2247047-77-2
DC65571 FY-21 Featured

FY-21 is a selective inhibitor of LSD1.

DC65572 Anti-inflammatory agent 51 Featured

Anti-inflammatory agent 51 (compound 11d) is an amide/sulfonamide derivative with anti-inflammatory activities.

2911610-03-0
DC65573 WES-1 Featured

WES-1 (Compound 8g) is an inhibitor of carbonic anhydrase IX (Ki: 55.9 μM).

2748673-86-9
DC65574 Anti-NASH agent 1 Featured

Anti-NASH agent 1 (compound 3d),a derivative of Elafibranor (HY-16737),is a potent agonist of PPAR-α/δ.

2409685-41-0
DC65575 17β-HSD10-IN-2 Featured

17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor.

2316765-79-2
DC65576 17β-HSD10-IN-1 Featured

17β-HSD10-IN-1 (compound 9) is an orally active inhibitor of 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) with blood-brain permeability. 17β-HSD10-IN-1 doesn't result additional effects for mitochondrial off-targets and cytotoxic or neurotoxic effects.

2316765-78-1
DC65577 P-Gb-In-1 Featured

P-gb-IN-1 (compound Ⅲ-8), a 2,5-disubstituted furan derivative, is a highly effective, broadspectrum P-glycoprotein (P-gp) inhibitor.

2632874-49-6
DC65578 ROS inducer 1 Featured

ROS inducer 1 (compound I29) is a fungicide, with EC50 against Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo), and Pseudomonas syringae pv. actinidiae (Psa)

2921602-31-3
DC65579 h-NTPDase8-IN-1 Featured

h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8

716358-51-9
DC65580 AD-186 Featured

AD186 is a potent and selective S1R agonist

DC65581 AP-C2 Featured

AP-C2 is a potent guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor.

682793-07-3
DC65582 Cbl-b-IN-5 Featured

Cbl-b-IN-5 (compound 6) is a Cbl-b inhibitor.

2368835-59-8
DC65583 Nurr1 agonist 2 Featured

Nurr1 agonist 3 (Compound 7) is a Nurr1 agonist.

742058-34-0
DC65584 Antitumor agent-93 Featured

Antitumor agent-93 (compound 7D) is an anticancer agent.

1681019-44-2
DC65585 Sotuletinib dihydrochloride Featured

Sotuletinib, also known as BLZ945, is a potent and selective CSF-1R kinase inhibitor. BLZ945 showed effects of CSF1R inhibition on other tumor-infiltrating immune cells. BLZ945 attenuates the turnover rate of TAMs while increasing the number of CD8+ T cells that infiltrate cervical and breast carcinomas. BLZ945 decreases the growth of malignant cells in the mouse mammary tumor virus-driven polyomavirus middle T antigen (MMTV-PyMT) model of mammary carcinogenesis. BLZ945 prevents tumor progression in the keratin 14-expressing human papillomavirus type 16 (K14-HPV-16) transgenic model of cervical carcinogenesis.

2222138-40-9
DC65586 B-Raf IN 15 Featured

B-Raf IN 15 (Compound 7) is a BRAF inhibitor.

832107-31-0
DC65587 ARC7 Featured

ARC7 can act as a probe for secondary metabolism in S. coelicolor.

681212-58-8
DC65588 5-LOX-IN-2 Featured

5-LOX-IN-2 is an inhibitor of 5-lipoxygenase (5-LOX).

179691-97-5
DC65589 AKT-IN-18 Featured

AKT-IN-18, an inhibitor of Akt, inhibits Akt.

DC65590 Antitumor agent-113 Featured

Antitumor agent-113 shows cytotoxic effects on A549 cells.

DC65595 Ethidium bromide Featured

Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.

1239-45-8
DC65596 GDC-0068 (dihydrochloride) Featured

Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.

1396257-94-5
DC65597 T807 Featured

T807 a novel tau positron emission tomography (PET) tracer.

1415379-56-4
DC65598 2-Chloro-3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Featured

1799612-10-4
DC65599 E3 ligase Ligand-Linker Conjugates 3 Featured

E3 ligase Ligand-Linker Conjugates 3 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.

2101200-09-1
DC65600 42-(2-Tetrazolyl)rapamycin Featured

42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.

221877-56-1
DC65601 Hoechst 33342 Featured

Hoechst 33342 is a DNA minor groove binder used fluorochrome for visualizing cellular DNA.

23491-52-3
DC65602 BMS-309403 sodium Featured

BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells.

2802523-05-1
DC65603 Mepazine Featured

Mepazine (Pecazine) is a potent and selective MALT1 inhibitor. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 and 0.42 μM, respectively. Mepazine affects viability of ABC-DLBCL cells by enhancing apoptosis.

60-89-9
DC65604 L-Buthionine (S,R)-sulfoximine Featured

L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.

83730-53-4
DC60491 C11-MRTX Featured

C11-MRTX is a lipid-conjugated MRTX849 analogue with a 11-carbon tail. C11-MRTX is a nonaggregating potent cellular inhibitor of K-Ras(G12C).

DC65591 Pim-1 kinase inhibitor 4 Featured

Pim-1 kinase inhibitor 4 (Compound 10f) is a Pim-1 kinase inhibitor.

DC65592 AChE-IN-30 Featured

AChE-IN-30 is an AChE inhibitor.

2937454-22-1
124608 EN450 Featured

EN450 is a cysteine-reactive covalent molecular glue degrader targeting NF-κB.

793719-01-4
DC65594 Anticancer agent 129 Featured

Anticancer agent 129 (Compound 3a), a quinoline derivative, predicting to has anti-cancer activity.

135882-37-0
DC65605 WAY-299359 Featured

WAY-299359 is a FLT3 inhibitor

1005057-81-7
DC65606 WAY-304800-A Featured

WAY-304800-A is a Casein kinase 1δ inhibitor.

345616-08-2
DC65607 WAY-311474 Featured

WAY-311474 altering the lifespan of eukaryotic organisms.

569313-77-5
DC65608 WAY-625135 Featured

WAY-625135 is a Casein kinase 1δ inhibitor.

756865-45-9
DC65609 WAY-646458 Featured

WAY-646458 is a Casein kinase 1d inhibitor.

852413-92-4
DC65610 WAY-270250 Featured

WAY-270250 is a IGF-1R/SRC inhibitor.

852367-46-5
DC65611 WAY-299562 Featured

WAY-299562 is a modulator of the interaction of protein kinase A (PKA) and A kinase anchor proteins (AKAP).

299934-88-6
DC65612 Lenalidomide-acetylene-Br Featured

Lenalidomide-acetylene-Br is a PROTAC Linker that makes up HJM-561.

2619512-84-2
DC65613 LZWL02003 Featured

LZWL02003 is a neuroprotective agent and derivative of N-salicyloyl tryptamine. LZWL02003 upregulated the expression of Bcl-2 and downregulated the expression of Bax, thus maintaining the homeostasis of Bcl-2/Bax proteins and preventing apoptosis. LZWL02003 also reduced oxidative stress by reducing malondialdehyde and reactive oxygen species levels, increasing the superoxide dismutase activity, and resolving mitochondrial malfunction. LZWL02003 can lower interleukin (IL)-1β, tumor necrosis factor (TNF)-α, and IL-6 levels, which in turn suppress neuroinflammation. LZWL02003 suppressed the phosphorylation activation of NF-κB pathway-related proteins and decreased the nuclear translocation of NF-κB p65 subunits. LZWL02003 is a neuroprotective agent with pleiotropic effects and may be a candidate for treating cerebral I/R injury.

1371564-45-2
DC65614 AJ2-30 Featured

AJ2-30 is a SLCl5A4 inhibitor.

2700322-79-6
DC65615 AJ2-71 Featured

AJ2-71 is a SLCl5A4 inhibitor.

2700323-17-5
DC65616 JC-229 Featured

JC-229 is a TbRPA1 inhibitor. JC-229 targets RPA1 in Trypanosoma brucei, the causative parasite of African trypanosomiasis. JC-229 is highly toxic to T. brucei cells, while mildly toxic to human cells. JC-229 treatment mimics the effects of TbRPA1 depletion, including DNA replication inhibition and DNA damage accumulation. JC-229 inhibits the activity of TbRPA1, but not the human ortholog.

DC65617 TH-Z93 Featured

TH-Z93, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 90 nM).

2260887-09-8
DC60492 244cis Featured

244-cis is an ionizable, liver-specific lipid. 244-cis LNP that induces lower immune responses than the responses evoked by previously used LNPs. 244-cis LNP and low-dose adeno-associated virus could minimize side effects and achieve a therapeutic threshold in hemophilia A mice.

2956402-64-3
DC60493 BEBT-809 Featured

BEBT-809 is a GPR75 antagonist for rat CYP4F2 and CYP4A11 with IC50 of and 15.76 nM and 33.16 nM, respectively.

DC60494 76-O17Se Featured

76-O17Se is a lipidoid for the efficient delivery of antiCD19 mRNA CAR to murine primary macrophages. 76-O17Se is more efficient than delivery with lipofectamine 2000 (LPF2K) or MC3

DC60495 9322-O16B Featured

9322-O16B is a lipidoid for the efficient delivery of antiCD19 mRNA CAR to murine primary macrophages. LNP 9322-O16B is more efficient than delivery with lipofectamine 2000 (LPF2K) or MC3.

2909427-23-0
DC65618 DSPE-NHS Featured

DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as drug nanocarrier.

1383932-86-2
DC65619 LNP Lipid-8 Featured

LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells without targeting to ligands. LNP LIPs-8 loaded with GFP siRNA (siGFP), and significantly causes GFP gene silencing in mice model.

2408140-60-1
DC65620 cKK-E15 Featured

cKK-E15 is an ionizable cationic lipid and a derivative of cKK-E12 that has been used in the generation of lipid nanoparticles (LNPs).1 LNPs containing cKK-E15 and encapsulating Cre mRNA induce the expression of Cre in Kupffer cells, endothelial cells, and hepatocytes in Ai14 mice engineered to express the fluorescent protein tdTomato upon translation of Cre.

1432494-71-7
DC65621 1,2(R)-Dioleyloxy-3-dimethylamino-propane Featured

1,2(R)-Dioleyloxy-3-dimethylamino-propane ((R)-DODMA) is an ionizable cationic lipid and an isomer of DODMA

666234-78-2
DC65622 306Oi9-cis2 Featured

306Oi9-cis2 is an ionizable cationic lipid. WARNING This product is not for human or veterinary use.

3027930-39-5
DC65623 Lipid AX4 Featured

Lipid AX4 is an ionizable cationic lipid (pKa = 6.89) that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.

2735814-23-8
DC65624 RM 137-15 Featured

RM 137-15 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.1 LNPs containing RM 137-15 and encapsulating mRNA encoding a fluorescent reporter increase fluorescence in the livers of mice.

DC65625 C12-SPM Featured

C12-SPM is a polyamine branched-chain lipidoid.1 It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA targeting the host protein kinase protein kinase C-related kinase 2 (PRK2) to inhibit hepatitis C virus (HCV) replication in Huh7 cells and a mouse model of HCV infection.

2055647-81-7
DC65626 C14-SPM Featured

C14-SPM is a polyamine branched-chain lipidoid.1 It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA.

2241864-59-3
DC65629 Deslorelin Featured

Deslorelin is a GnRH agonist. Deslorelin implants can be used as an alternative to dopamine agonists to induce fertil eoestrus in the bitch in anoestrus. The deslorelin implant can be used successfully in the queen for oestrus inhibition. Deslorelin acetate did not significantly affect the spontaneous contraction amplitude but caused a decrease in the frequency in the dorsal and ventral parts of the bladder.

57773-65-6
DC65630 Melanotan II Featured

Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.

121062-08-6
DC65631 Teriparatide acetate Featured

Teriparatide is a PHT agonist, with an IC50 of 2 nM in HEK293 cells. Sequence: Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe.

99294-94-7
DC65632 Tetracosactide acetate Featured

Tetracosactide (INN) is an analogue of adrenocorticotrophic hormone (ACTH), with the biological activity of stimulating production of corticosteroids in the adrenal cortex. Sequence: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro.

16960-16-0
DC65634 LL 37 Featured

LL-37, Human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity[1]. LL-37, Human could help protect the cornea from infection and modulates wound healing.

154947-66-7
DC65636 Lypressin Featured

Lysipressin is Antidiuretic hormone that have been found in pigs and some marsupial families. Induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase.

50-57-7
DC60496 TT-012 Featured

TT-012 is a potent small-molecule MITF dimer disruptor. TT-012 diminishes the Alpha signal generated by MITF dimer formation is 13.1 nM. TT-012 also inhibits the transcriptional activity of MITF in B16F10 melanoma cells.

1164471-33-3
DC65637 Terlipressin GMP grade Featured

Terlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells. Terlipressin can result in splanchnic vasoconstriction augmenting systemic arterial blood pressure with beneficial circulatory and renal effects that would be expected to also ameliorate the key pathophysiological changes responsible for the development of refractory ascites

14636-12-5
DC65638 DSIP Featured

Delta-Sleep Inducing Peptide trifluoroacetate salt is a neuropeptide, with antioxidant and anxiolytic properties.

62568-57-4
DC65639 Thymulin Acetate Featured

Serum thymic factor (Thymulin) is a zinc-dependent immunomodulatory peptide. Serum thymic factor induces hyperalgesia. Serum thymic factor protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor has anti-diabetic, analgesic and anti-inflammatory effects.

63958-90-7
DC65640 Selank Featured

TP-7 (Selanc) is a heptapeptide with anxiolythic properties.

129954-34-3
DC65641 Larazotide Acetate Featured

Larazotide acetate is a synthetic peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state.

881851-50-9
DC65642 Thymosin beta 4 Featured

Thymosin beta 4 is a potent regulator of actin polymerization in living cells. Sequence: Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser.

77591-33-4
DC65643 Kisspeptin-10 Featured

Kisspeptin-10 is a potent endogenous agonist for GPR54, used as a vasoconstrictor and an angiogenesis inhibitor.

374675-21-5
DC65644 Nafarelin Featured

Nafarelin is a gonadotropin-releasing hormone (GnRH) agonist that stimulates secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Sequence: {Glp}-His-Trp-Ser-Tyr-{2-Naph-Ala}-Leu-Arg-Pro-Gly-NH2.

76932-56-4
DC65645 iRGD Featured

iRGD peptide is a 9-amino acid cyclic peptide, triggers tissue penetration of drugs by first binding to av integrins, then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties.

1392278-76-0
DC65646 Opiorphin trifluoroacetate salt Featured

Opiorphin, an opioid peptide, is a potent enkephalin-inactivating zinc ectopeptidases in human inhibitor. Opiorphin inhibits two enkephalin-catabolizing ectoenzymes, human neutral ecto-endopeptidase, hNEP (EC 3.4.24.11) with an IC50 value of 11 μM, and human ecto-aminopeptidase, hAP-N (EC 3.4.11.2). Opiorphin displays potent analgesic activity by activating endogenous opioid-dependent transmission.

864084-88-8
DC65647 Goralatide Featured

N-Acetyl-Ser-Asp-Lys-Pro is a natural and specific substrate for the N-terminal site of ACE.

127103-11-1
DC65648 Retatrutide GMP grade Featured

LY3437943 is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). LY3437943 inhibits for human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. LY3437943 can be used for the research of obesity.

2381089-83-2
DC65649 Adrenocorticotropic Hormone (ACTH) (1-39), human Featured

Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist.

12279-41-3
DC60497 STX-478 Featured

STX-478 is an allosteric PI3Kα inhibitor that selectively targets prevalent PI3Kα helical- and kinase-domain mutant tumors. STX-478 provides robust efficacy while avoiding the metabolic dysfunction associated with the nonselective inhibitor alpelisib.

2883540-92-7
DC65650 Vialox Featured

Pentapeptide-3 is a pentapeptide fragment of neurotoxin waglerin-1 from the venom of Temple Viper. Pentapeptide-3 is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs), it can blocks nerves at the post-synaptic membrane. Pentapeptide-3 has anti-aging effects and it can be used together with other cosmetic peptides.

135679-88-8
DC65651 Dipeptide-2 Featured

Dipeptide 2 (N-Valyltryptophan; Val-Trp) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient.

24587-37-9
DC65652 Palmitoyl tripeptide-5 bistrifluoracetate salt Featured

623172-56-5
DC65653 Palmitoyl tetrapeptide-7 Featured

Palmitoyl Tetrapeptide-3 (Rigin) is a synthetic peptide, corrspending to 341-344 amino acid sequenceof IgG human H-chain, with phagocytosis stimulating activity.

221227-05-0
DC65654 Hexapeptide-10 Featured

Hexapeptide-10 is an amino acid derivative.

146439-94-3
DC65655 BiotinoylTripeptide-1 Featured

Biotinoyl tripeptide-1 (Biotinyl-GHK; Bio-GHK)is a bioactive peptide with hair growth effect and has been reported used as a cosmetic ingredient.

299157-54-3
DC65656 Acetyl tetrapeptide-3 Featured

Acetyl tetrapeptide-3 is a bioactive chemical.

827306-88-7
DC65657 Palmitoyl hexapeptide-12 Featured

Palmitoyl hexapeptide-12 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient.

171263-26-6
DC65658 Nonapeptide-1 Featured

Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (Ki: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC50: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer.

158563-45-2
DC65659 Acetyl tetrapeptide-9 Featured

Caprooyl-tetrapeptide-9 (AcTP1) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient.

928006-50-2
DC65660 Hexapeptide-9 Featured

1228371-11-6
DC65661 Acetyl hexapeptide 38 Featured

Acetyl hexapeptide-38 is a bioactive peptide with upregulate adipogenesis effect and has been reported used as a cosmetic ingredient.

1400634-44-7
DC65662 L-carnosine Featured

L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging.

305-84-0
DC65663 Melitane Featured

Acetyl hexapeptide-1 (Melitane) is a bioactive peptide with anti-wrinkle effect and has been reported used as a cosmetic ingredient.

448944-47-6
DC60498 UNC8153 Featured

UNC8153 is a novel NSD2-targeted degrader that potently and selectively reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark.

DC65664 Palmitoyl tripeptide-38 Featured

Palmitoyl tripeptide-38 is a bioactive peptide with anti-aging effect .

1447824-23-8
DC65665 Palmitoyl Tripeptide-8 Featured

Palmitoyl tripeptide-8 s a bioactive peptide with anti-allergen effect and has been reported used as a cosmetic ingredient.

936544-53-5
DC65666 Tripeptide-1 Featured

72957-37-0
DC65667 AHK-Cu Featured

682809-81-0
DC65668 Mu-conotoxin Featured

μ-Conotoxin-CnIIIC is a 22-residue conopeptide that can be isolated from Conus consors. μ-Conotoxin-CnIIIC is a potent and persistent blocker of NaV1.4 channel. μ-Conotoxin-CnIIIC has analgesic, anaesthetic and myorelaxant properties.

936616-33-0
DC60499 C14-A1 Featured

Lipid C14-A1 is an ionizable lipid. C14-A1-LPN is a potent and safe LNP platform to deliver Foxp3 mRNA to CD4+ T cells to engineer immunosuppressive FP3T cells.

DC65669 TB500 Featured

TB500 is a synthetic version of an active region of thymosin β4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation.

885340-08-9
DC60500 NVS-STG2 Featured

NVS-STG2 is a molecular glue that targets STING and activates STING-mediated immune signaling. NVS-STG2 induces higher-order oligomerization of human STING by binding to pockets between adjacent STING dimer transmembrane domains, effectively acting as a molecular glue. NVS-STGI enhances the activity of cGAMP by inducing the formation of more abundant and larger oligomers. NVS-STG2 produces antitumor activity in animal models.

3030588-01-0
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