Cat. No. | Product name | CAS No. |
DC11275 |
Calicheamicin
Featured
Calicheamicin, also known as Calicheamicin gamma(1,I) or Calichemicin gamma1, is an potent enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora. Calicheamicin targets DNA and cause strand scission. Calicheamicin binds with DNA in the minor groove, wherein it then undergos a reaction analogous to the Bergman cyclization to generate a diradical species. This diradical, 1,4-didehydrobenzene, then abstracts hydrogen atoms from the deoxyribose (sugar) backbone of DNA, which ultimately leads to strand scission. The specificity of binding of calicheamicin to the minor groove of DNA is due to the aryltetrasaccharide group of the molecule. |
108212-75-5 |
DC20021 |
Calmidazolium chloride (R 24571)
Featured
Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively. Also in anti-cancer re |
57265-65-3 |
DC7095 |
W-7 hydrochloride
Featured
Calmodulin antagonist. Inhibits Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 μM) and myosin light chain kinase (IC50 = 51 μM). |
61714-27-0 |
DC7967 |
calpeptin
Featured
calpeptin is Ca2+-dependent protease,calpain inhibitor |
117591-20-5 |
DC8730 |
Cambendazol
Featured
Cambendazol is an antihelmintic that, at a dose of 50 mg/kg/day in mice, eradicates S. ratti adult worms from intestine and S. stercoralis larva from muscle. |
26097-80-3 |
DC10744 |
Cambinol
Featured
Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 and 59 μM, respectively. |
14513-15-6 |
DC20859 |
CAN-508
Featured
CAN-508 is a potent, selective CDK9 inhibitor with IC50 of 0.35 uM (CDK9/cyclin T1), displays >35 fold selectivity over CDK1/2/4/7 (IC50=13.5-70 uM). |
140651-18-9 |
DC3111 |
Canagliflozin
Featured
Canagliflozin is a highly potent and selective SGLT2 inhibitor for CHO-hSGLT2, CHO-rSGLT2 and CHO-mSGLT2 with IC50 of 4.4 nM, 3.7 nM and 2 nM, respectively. |
842133-18-0 |
DC9185 |
Candesartan cilexetil
Featured
Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. |
145040-37-5 |
DC8553 |
Canertinib
Featured
Canertinib (CI-1033) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3. CI-1033 shows excellent potency for irreversible inhibition of erbB2 autophosphorylation in MDA-MB |
267243-28-7 |
DC3138 |
Canertinib dihydrochloride
Featured
Canertinib dihydrochloride is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. |
289499-45-2 |
DC22425 |
Cangrelor sodium
Featured
Cangrelor (AR-C69931MX) is a potent, selective P2T/P2Y12 receptor antagonist with IC50 of 0.4 nM against ADP-induced aggregation of human platelets. |
163706-36-3 |
DC7005 |
Cangrelor free acid
Featured
Cangrelor is a P2Y12 inhibitor, and was approved in June 2015 as an antiplatelet drug for intravenous application. Cangrelor is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggrega |
163706-06-7 |
DC4154 |
Capecitabine
Featured
Capecitabine is a tumor-selective fluoropyrimidine carbamate which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU. |
154361-50-9 |
DC7615 |
Capromorelin
Featured
Capromorelin tartrate is a potent ghrelin receptor agonist/growth hormone secretagogue (Ki = 7 nM). |
193273-69-7 |
DC7952 |
Capasazepine
Featured
Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, capsaicin; potent TRPV1 receptor antagonist with IC50 of 562 nM. |
138977-28-3 |
DC9193 |
Carbamazepine
Featured
Carbamazepine, a sodium channel blocker, is an anticonvulsant drug. |
298-46-4 |
DC9095 |
Carboplatin
Featured
Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell's repair mechanism. |
41575-94-4 |
DC9384 |
Carboxypeptidase G2 (CPG2) Inhibitor
Featured
Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents. |
192203-60-4 |
DC6502 |
cardamonin
Featured
Cardamonin, isolated from the fruits of Alpinia species, is a chalconoid with anti-inflammatory and anti-tumor activity. |
19309-14-9 |
DC8456 |
Cardiogenol C (hydrochloride)
Featured
Cardiogenol C is a diaminopyrimidine that induces cardiomyogenesis in mouse embryonic stem cells. |
671225-39-1 |
DC1002 |
Carfilzomib (PR-171)
Featured
Carfilzomib is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells,showed potent activity against COVID-19(SARS-COV-2). |
868540-17-4 |