| DC7695 |
Defactinib (VS-6063, PF-04554878)
Featured
|
Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel. |
|
| DC10100 |
Defactinib hydrochloride
Featured
|
Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel. |
|
| DC10822 |
Defensamide(MHP)
Featured
|
Defensamide, also known as MHP and methyl caprooyl tyrosinate, is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC. |
|
| DCAPI1107 |
Deferasirox (Exjade)
Featured
|
Deferasirox (Exjade) |
|
| DC7399 |
Deferitrin
Featured
|
Deferitrin (GT-56-252) is the first drug in a class of desferrithiocin-derived hexadentate iron chelators. |
|
| DC11332 |
Degarelix (acetate)
Featured
|
Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist (IC50 = 3 nM in HEK293 cells expressing the human receptor). |
|
| DC9337 |
Deguelin
Featured
|
Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to have an anti-tumor effect on several cancers; decrease levels of phosphorylated Akt.
|
|
| DC8866 |
DEL-22379
Featured
|
DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ∼0.5 μM. |
|
| DC10458 |
Delafloxacin（ABT-492）
Featured
|
Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. |
|
| DC20116 |
Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine)
Featured
|
Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and |
|
| DC7764 |
Delamanid (OPC-67683)
Featured
|
Delamanid (OPC-67683) is an experimental drug for the treatment of multi-drug-resistant tuberculosis. |
|
| DC8481 |
Delanzomib(CEP-18770)
Featured
|
Delanzomib(CEP-18770) is a novel orally-active inhibitor of the chymotrypsin-like activity of the proteasome that down-modulates the nuclear factor-kappaB (NF-kappaB) activity. |
|
| DC11890 |
Delgocitinib
Featured
|
Delgocitinib (JTE-052, LEO 124249) is a potent, selective, orally active, pan-JAK inhibitor with IC50 of 2.8, 2.6, 13 and 58 nM for JAK1,2,3 and Tyk2, respectively. |
|
| DC10612 |
Delpazolid (LCB01-0371)
Featured
|
Delpazolid (LCB01-0371) is a new oxazolidinone with cyclic amidrazone. |
|
| DC8205 |
Deltarasin
Featured
|
Deltarasin is a novel and small molecule inhibitor which can inhibit the KRAS-PDEδ interaction(Kd= 41 nM. binding to PDEδ) and impairs oncogenic KRAS signalling. |
|
| DC26004 |
delta-Valerobetaine (hydrobromide)
Featured
|
Delta-Valerobetaine (hydrobromide) is a precursor of trimethylamine N-oxide (TMAO). |
|
| DC12287 |
delta-Valerobetaine
Featured
|
Delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO). |
|
| DC8712 |
Deoxycorticosterone acetate
Featured
|
Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. |
|
| DC10559 |
Derazantinib (ARQ 087)
Featured
|
Derazantinib (Derazantinib) is an ATP competitive tyrosine kinase inhibitor; exhibits potent activity against FGFR1-3 chondrocytes with IC50s of 4.5, 1.8, and 4.5 nM, respectively. |
|
| DC24197 |
Derenofylline(SLV320)
Featured
|
Derenofylline(SLV320) is a potent and selective adenosine A1 receptor antagonist (Ki values are 1, 200, 398 and 3981 nM at human A1, A3, A2A and A2B receptors respectively). |
|
| DC11402 |
Desidustat
Featured
|
Desidustat is an inhibitor of HIF hydroxylase. |
|
| DC11055 |
Desmethyl dabrafenib
Featured
|
Desmethyl dabrafenib (GSK2167542, Dabrafenib metabolite M8) is the desmethyl- metabolic byproduct of Dabrafenib, ameliorates developmental pathologies of Kabuki Syndrome in vivo.. |
|
| DC8833 |
Desmethyl VS-5584
Featured
|
Desmethyl VS-5584 is a PI3K/mTOR kinase inhibitor |
|
| DC9604 |
Desogestrel
Featured
|
Desogestrel(Org-2969) is a third-generation 19-nortestosterone derivative progestogen; is contained in many oral contraceptive preparations, both combined (COCs) to ethinyl-estradiol (EE) or alone in a progestin-only pill (POP). |
|
| DC20273 |
Deuterated AZ5104
Featured
|
Deuterated AZ5104 is a potent EGFR inhibitor. |
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|
| DCAPI1025 |
Dexamethasone
Featured
|
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs used as an anti-inflammatory and immunosuppressant. |
|
| DC4240 |
Dexmedetomidine hydrochloride
Featured
|
Dexmedetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties. |
|
| DC22074 |
DFP00173
Featured
|
DFP00173 (DFP-00173) is a potent and selective aquaporin-3 (AQP3) inhibitor, inhibits glycerol permeability in
erythrocytes with IC50 of 0.2 uM.. |
|
| DC24079 |
DG-172 dihydrochloride
Featured
|
DG-172 is a novel PPARβ/δ-selective ligand showing high binding affinity (IC50= 27 nM) and potent inverse agonistic properties. |
|
| DC12321 |
STING agonist-1 trihydrochloride
Featured
|
diABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist. |
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