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Cat. No.	Product Name	Field of Application
DC10936	GSK3179106 Featured	GSK3179106 (GSK-3179106, GSK 3179106) is a potent, selective, first-in-class and gut-restricted with IC50 of 0.4 and 11 nM in the biochemical assay and cellular assay respectively.
DC10647	EPZ015938(pemrametostat) Featured	GSK3326595(EPZ015938) is the first-in-class protein arginine methyltransferase-5 (PRMT5) inhibitor.
DC7143	GSK-343 Featured	GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM, showing 60 fold selectivity against EZH1, and >1000 fold selectivity against other histone methyltransferases.
DC8505	GSK369796 Featured	GSK369796 shows antimalerial activity with IC50 values of 11.2 nM for 3D7 strain, 12.6 nM for HB3 strain, 17.6 nM for K1 strain
DC1035	GSK3787 Featured	GSK3787 is as a potent and selective antagonist of PPARδ with pIC50 of 6.6.
DC8648	GSK4112 Featured	GSK4112 is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.
DC7144	GSK429286A Featured	GSK429286A is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63 nM, respectively.
DC22306	cGAS inhibitor 467 Featured	GSK467 is a potent and selective inhibitor of KDM5 (also known as JARID1). GSK467 exploits unique binding modes.
DC8589	PAD4 inhibitor GSK484 Featured	GSK484 is a reversible inhibitor of PAD4 (IC50 = 50 nM) that binds to the low-calcium form of the enzyme.
DC8044	GSK503 Featured	GSK503 is a specific EZH2 methyltransferase inhibitor.
DC12513	RIP1 inhibitor GSK547 Featured	GSK547 (RIP1i, GSK 547) is a highly selective and potent inhibitor of RIP1 kinase that robustly targets RIP1 in vivo.
DC9733	GSK583 Featured	GSK583 is a Highly Potent and Selective Inhibitor of RIP2 Kinase (RIP2K bing IC50=5 nM; rat in vivo PD IC50 = 50 nM).
DC9831	GSK6853 Featured	GSK6853 is a potent, soluble, cell active, and highly selective inhibitor of the BRPF1 bromodomain
DC2070	GSK690693 Featured	GSK690693 is a pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 2 nM, 13 nM, and 9 nM, respectively.
DC8373	GSK8573 Featured	GSK-8573 is the inactive control of GSK-2801.
DC26130	GSK8612 Featured	GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1.
DC10471	GSK-872 Featured	GSK-872 is a potent and selective RIPK3 (receptor-interacting protein kinase-3) inhibitor.
DC7812	GSK923295 Featured	GSK923295 is a first-in-class, specific allosteric inhibitor of CENP-E kinesin motor ATPase with Ki of 3.2 nM, and less potent to mutant I182 and T183.
DC9907	GSK9311 Featured	GSK9311 is a potent and highly selective inhibitor of the BRPF bromodomain (BRPDF1 pIC50 = 6.0; BRPDF2 pIC50 = 4.3).
DC10061	PI4KA inhibitor-A1 Featured	GSK-A1 is a potent inhibitor of PI4KA. In vitro using HEK-AT1 cells, GSK-A1 had an IC50 of about 3 nM.
DC10064	GSK-F1 Featured	GSK-F1 is a potent inhibitor of PI4KA.
DC7858	GSK-J1 Featured	GSK-J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM for human JMJD3 in vitro).
DC7857	GSK-LSD1 Featured	GSK-LSD1 is a potent and selective inhibitor of lysine specific demethylase 1 (LSD1).
DC20112	GT 949 Featured	GT 949 is a selective excitatory amino acid transporter-2 (EAAT2) positive allosteric modulator with an EC50 of 0.26 nM.
DC8303	GTS 21 2HCl(DMXBA) Featured	GTS 21 dihydrochloride is a partial agonist of α7 nicotinic acetylcholine receptors (nAChRs); also a weak α4β2 and 5-HT3 antagonist at micromolar concentrations.
DC21825	Guanabenz Featured	Guanabenz (WY 8678) is an α2 adrenergic receptor agonist that is used as an antihypertensive agent, also has been proposed to exert protective effects against misfolding by interfering with eIF2α-P dephosphorylation through selective disruption of a PP1-P
DC9819	Guanoclor Featured	Guanoclor is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.
DC7566	GW-4064 Featured	GW 4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).
DC7145	GW441756 Featured	GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2.
DC8810	GW-5074 Featured	GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor (IC50 = 9 nM); displays ≥ 100-fold selectivity for raf kinase over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fms.

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