| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11531 | Teslexivir | A first-in-class, small molecule protein-protein inhibitor of the interaction between the E1 and E2 proteins of HPV types 6 and 11. |
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| DC12012 | PD 404182 Featured | PD 404182 is a high affinity inhibitor of KDO 8-P synthase (Ki = 26 nM). Also inhibits dimethylarginine dimethylaminohydrolase 1 (DDAH1). Exhibits antiangiogenic and antiviral activity in vitro. Putative antibiotic against gram-negative bacteria. |
|
| DC11823 | BMS-929075 | A highly potent, selective, orally bioavailable HCV NS5B polymerase inhibitor with IC50 of 9, 4, and 18 nM for GT1a, GT1b, and GT1b-C316N mutant in HCV replicon assay, respectively. |
|
| DC11811 | SCY-078 | A novel orally bioavailable fungal beta-1,3-D glucan synthetase inhibitor against Candida species C. glabrata (MIC 0.03 to 0.25 ug/ml), C. parapsilosis (MIC 0.06 to 0.25 ug/ml). |
|
| DC11854 | IDX899 | A novel potent, selective HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with EC50 of 1, 1.3, 2.8 and 11 nM for WT, K103N, Y181C and K103N/Y181C, respectively. |
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| DC11825 | MK-8876 | A novel, broadly acting non-nucleoside inhibitor of HCV NS5B polymerase with IC50 of 3 nM and 2 nM for GT1b and GT2a, respectively. |
|
| DC11772 | AZD-4316 | A potent respiratory syncytial virus (RSV) fusion inhibitor.. |
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| DC11647 | JNJ-2408068 Featured | JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1]. |
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| DC24010 | Plpro-IN-6(PLpro inhibitor) Featured | A potent, noncovalent SARS-CoV papain-like protease (PLpro) inhibitor with IC50 of 2.6 uM. |
|
| DC11731 | Ruzasvir | A potent, pan-genotype HCV NS5A inhibitor with replicon EC90 of 0.003, 0.016, 0.067, 0.036, 0.007, and 0.007 nM for GT1a, GT1a L31V, GT1a Y93H, GT2b, GT3a, and Gt4a, respectively.. |
|
| DC11849 | DSM421 | A potent, selective P. falciparum dihydroorotate dehydrogenase (PfDHODH) with IC50 of 53 nM. |
|
| DC21979 | ATF6 agonist compound A147 Featured | ATF6 agonist compound A147 is a specific, small molecule agonist of transcription factor ATF6, activates ATF6 and influences differentiation of stem cells.147 has broad antiviral activity against multiple DENV strains and serotypes and that the compound i |
|
| DC10797 | AB-423 Featured | AB-423 is the first-generation Hepatitis B Virus Capsid Assembly inhibitor, which was generally safe and well tolerated in Phase 1 healthy volunteer studies. |
|
| DC9029 | Abacavir | Abacavir is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. |
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| DCAPI1273 | Acyclovir (Aciclovir) | Acyclovir (Aciclovir) |
|
| DC10513 | AFN-1252(Debio 1452) Featured | AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml. |
|
| DC10621 | Amenamevir Featured | Amenamevir, also known as ASP2151, is a herpes virus helicase-primase inhibitor. |
|
| DC7058 | Amprenavir Featured | Amprenavir (Agenerase) is a HIV protease inhibitor(Ki=0.6 nM) used to treat HIV infection. |
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| DC11738 | SCYX-7158 | An orally-active, CNS permeable benzoxaborole antiprotozoal agent. |
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| DC9827 | AN3365(Epetraborole) Featured | AN3365 is a first-in-class antibiotic that demonstrates potent activity across a wide spectrum of Gram-negative bacteria, including those resistant to many other antibiotics. |
|
| DCAPI1051 | Arbidol HCl (Umifenovir) Featured | Umifenovir is currently being investigated as a potential treatment and prophylactic agent for COVID-19 caused by SARS-CoV2 infections in combination with both currently available and investigational HIV therapies. Arbidol hydrochloride (Umifenovir hydroc |
|
| DC3150 | Atazanavir Featured | Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM. |
|
| DC9480 | Atazanavir (sulfate) | Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. |
|
| DCAPI1362 | Azithromycin (Zithromax) | Azithromycin (Zithromax) |
|
| DC7541 | Balapiravir | Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). |
|
| DC11056 | Baloxavir marboxil Featured | Baloxavir marboxil is a prodrug of S-033447. S-033447 is a small molecule inhibitor of the cap-dependent endonuclease of influenza A and B viruses. |
|
| DC5064 | Baricitinib (INCB28050, LY3009104) Featured | Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2,showed potent activity against COVID-19(SARS-COV-2). |
|
| DC8258 | Baricitinib phosphate Featured | Baricitinib phosphate(INCB 028050; LY 3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2,showed potent activity against COVID-19(SARS-COV-2). |
|
| DC10294 | Bay 41-4109 | BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM. |
|
| DC8809 | Bedaquiline fumarate Featured | Bedaquiline fumarate(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis. |
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