Novel potent inhibitor of eleven-nineteen leukemia (ENL) protein, selectively targeting the ENL YEATS domain

Novel oral inhibitor of angiogenic and proliferation kinases, having activity in recurrent, platinum resistant ovarian cancer

Novel potent inhibitor of ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1 or NPP1), showing good in vitro potency, stability in SGF/SIF/PBS, selectivity, ADME properties and pharmacokinetic profile and finally potent anti-tumor response in viv

PGE2 analog, inhibiting gastric acid secretion

Dopamine D2-receptor agonist for the treatment of extrapyramidal disorders, also being an antiparkinson agent

Novel β-tubulin polymerization inhibitor

Novel inhibitor of Ectonucleoside Triphosphate Diphosphohydrolase 5 (ENTPD5)

Novel inhibitor of Ectonucleoside Triphosphate Diphosphohydrolase 5 (ENTPD5)

Unnatural verticilide enantiomer, inhibiting type 2 ryanodine receptor-mediated calcium leak and being antiarrhythmic.

Novel, potent, and selective Factor XIa inhibitor

Vitamin E derivative, suppressing inflammation during hepatic ischemia-reperfusion injury and exerting hepatoprotective effects

Novel potent and selective leucyl-tRNA synthetase inhibitor

Novel agonist of EphA2 receptor tyrosine kinase

Potent and selective covalent inhibitor of receptor tyrosine kinase EphB1

Novel clickable potent and specific inhibitor of EphB3

The first potent and specific inhibitor of a single Eph isoform EphB3

Novel selrctive SETD8 inhibitor without inhibiting G9a, SETD7, RmtA, and PRMT1

Novel stabilizer of 14-3-3 PPIs, Diastereoepimer of aminopeptidase inhibitor bestatin

Second-generation antihistamine and mast cell stabilizer, being highly selective for the H1 receptor

The precursor of the nocardicins

Mucolytic and bronchospasm relieving agent

Novel inhibitor of extracellular polymeric substances (EPS)