Home > Products > Novel inhibitors
Cat. No. Product name CAS No.
DCC4565 S-8921

Novel ileal Na /bile acid cotransporter inhibitor

151165-96-7
DCC4566 Sab378

Peripherally restricted cannabinoid CB1/CB2 receptor agonist, inhibiting gastrointestinal motility with no effect on experimental colitis in mice

432047-72-8
DCC4567 Safrazine Hydrochloride

Irreversible and nonselective Monoamine_oxidase_inhibitor>monoamine oxidase inhibitor (MAOI)

7296-30-2
DCC4568 Sag1.5

Novel Smoothened receptor agonist

612542-14-0
DCC4569 Saha-bpyne

Novel clickable HDAC inhibitor, selectively labeling HDAC complex proteins

930772-88-6
DCC4570 Saha-obp

Novel Endogenous Reactive oxygen species (ROS)-activated HDAC inhibitor prodrug, demonstrating selective activity against multiple cancer cell lines such as HeLa, MCF-7, MDA-MB-231 and B16-F10, while remaining benign to non-cancer cells

DCC4571 Salacinol

Natural α-glucosidase inhibitor

200399-47-9
DCC4572 Salazinic Acid

Natural α-glucosidase inhibitor, potently modulating Nrf 2 , NF-κB and STAT3 pathways

521-39-1
DCC4573 Salbutamol

ß2-adrenoceptor agonist

18559-94-9
DCC4574 Salinomycin Sodium

Antibiotic, Inhibiting CD44 expression in breast cancer cells and mammary tumor growth

55721-31-8
DCC4575 Saliphe

Novel potent V-ATPase inhibitor, blocking viral entry

DCC4576 Samidorphan L-malate

Opioid receptor antagonist for the treatment of alcoholism and cocaine addiction

1204592-75-5
DCC4577 Sampangine

Natural antimicrobial and antitumor agent, inducing reactive oxygen species (ROS), and alterating heme biosynthesis

116664-93-8
DCC4578 Sampatrilat

Vasopeptidase or dual inhibitor of ACE and neutral endopeptidase with potential application in the treatment of hypertension and congestive heart failure

129981-36-8
DCC4579 Sansanmycin

Uridyl peptide antibiotic, exhibiting antibacterial activity against Mycobacterium tuberculosis H(37)Ra and Pseudomonas aeruginosa with MIC values of 10 and 12.5 mug/ml, respectively

DCC4580 Sant-2

Novel potent inhibitor of Shh signaling pathway

496793-78-3
DCC4581 Sap2-in-23h

Novel Potent Non-peptidic Inhibitor of Secreted Aspartic Protease 2 (SAP2) for the Treatment of Resistant Fungal Infections

DCC4582 Saperconazole

Broad-spectrum antifungal agent, selective inhibiting the cytochrome P-450-dependent ergosterol synthesis in Candida albicans, Aspergillus fumigatus and Trichophyton mentagrophytes, in vitro and in vivo activity against F. pedrosoi

110588-57-3
DCC4583 Sar-104772

Novel inhibitor of TAFIa (activated thrombin-activatable fibrinolysis inhibitor)

1437501-99-9
DCC4584 Sar107375

Novel selective and potent dual inhibitor of thrombin and factor Xa

DCC4585 Sarafloxacin

Broad spectrum antibiotic

98105-99-8
DCC4586 Sarcolipin

Regulator of the sarco-endoplasmic reticulum Ca -ATPase (SERCA1a), significantly slowing down the E2 to Ca2.E1 transition of SERCA1a while it affects neither phosphorylation nor dephosphorylation

145018-73-1
DCC4587 Sarcolipin Palmitoylated

Regulator of the sarco-endoplasmic reticulum Ca -ATPase (SERCA1a), significantly slowing down the E2 to Ca2.E1 transition of SERCA1a while it affects neither phosphorylation nor dephosphorylation

DCC4588 Sard033

Novel Highly Potent Selective Androgen Receptor Degrader (SARD)

DCC4589 Sard279

Novel Potent Selective Androgen Receptor Degrader (SARD)

DCC4590 Sarmustine

Covalent Antineoplastic Agent

81965-43-7
DCC4591 Sars-cov 3clpro-in-7d

Novel potent SARS-CoV-2 3CLpro inhibitor with IC 50 value of 73 nM

DCC4592 Sars-cov-2 Mpro Inhibitor E24

Novel SARS-CoV-2 Main Protease (Mpro) Inhibitor, inhibiting viral replication with a nanomolar EC 50 value (844 nM) in SARS-CoV-2-infected Vero E6 cells, impairing SARS-CoV-2 replication in human lung epithelial cells and human-induced pluripotent stem ce

DCC4593 Sars-cov-2 Nsp14 Mtase Inhibitor 16

Novel SARS-CoV-2 nsp14 Methyltransferase inhibitor

DCC4594 Sars-cov-2 Nsp14/16 Inhibitor 2a

Novel potent SARS-CoV-2 MTase Nsp14 and Nsp16 inhibitor

DCC4595 Satavaptan

Selective non-peptide vasopressin V2 receptor antagonist

185913-78-4
DCC4596 Satavaptan Fumarate

Selective non-peptide vasopressin V2 receptor antagonist

185913-79-5
DCC4597 Sat-in-3

Novel inhibitor of salmonella serine acetyltransferase (SAT), the enzyme that catalyzes the rate-limiting step of L-cysteine biosynthesis

898619-81-3
DCC4598 Saussureamine C

Inhibitor of H274Y and N294S mutants

148245-83-4
DCC4599 Sazetidine-a Dihydrochloride

Subtype-selective α4β2 nicotinic acetylcholine receptor partial agonist

820231-95-6
DCC4600 Sb1404

PPARγ covalent ligand

85469-93-8
DCC4601 Sb1495

Novel reversible covalent inhibitor of the cyclin-dependent kinase 5 (Cdk5)-mediated phosphorylation of PPARγ at Ser245, a key factor in the insulin-sensitizing effect of PPARγ-targeted drugs

DCC4602 Sb1617

Novel neuroprotective agent, suppressing abnormal tau protein aggregation

DCC4603 Sb-203347

Selective, active-site-directed 14 kDa PLA2 inhibitor, totally inhibiting LT and PAF formation, while prostanoid formation was not altered

DCC4604 Sb-209670

Dual ETA and ETB receptor antagonist

157659-79-5
DCC4605 Sb-220025 Trihydrochloride

Potent, specific inhibitor of human p38 mitogen-activated protein (MAP) kinase

197446-75-6
DCC4606 Sb-226552

Potent and selective agonist for the human ß3-adrenoceptor

883724-08-1
DCC4607 Sb-239272

Inhibitor of p38 MAPK

DCC4608 Sb-243213 Dihydrochloride

Selective 5-HT2C_receptor>5-HT2C inverse agonist

200940-23-4
DCC4609 sb-258719 Hydrochloride

Selective 5-HT7 receptor antagonist

195199-95-2
DCC4610 Sb2602

Novel selective mTOR inhibitor

DCC4611 Sb-267268

Nonpeptidic antagonist of alpha(v)beta3 and alpha(v)beta5 integrins, reducing angiogenesis and VEGF expression

205678-26-8
DCC4612 Sb-277011a Dihydrochloride

Selective dopamine D3 receptor antagonist

1226917-67-4
DCC4613 Sb-284851-bt

Selective p38a kinase inhibitor, inhibiting Brd4

219769-23-0
DCC4614 Sb-354364

AntiMycobacterium tuberculosis agent

DCC4615 Sb-390570

Novel TRPV4 blocker

DCC4616 Sb-414796

Potent and selective dopamine D3 receptor antagonist

264262-71-7
DCC4617 sb-649915

Novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor

420785-78-0
DCC4618 Sb-656933

Novel CXCR2 selective antagonist, inhibiting ex vivo neutrophil activation and ozone-induced airway inflammation in humans

688763-65-7
DCC4619 Sb-744941

Novel inhibitor of mitogen and Stress-Activated Kinases 1 (MSK1)

DCC4620 Sb-7720770 Dihydrochloride

Novel Rho kinase inhibitor

607373-46-6
DCC4621 Sb-790594-a

Potent non-cytotoxic inhinitor of Mycobacterium tuberculosis H37Rv

1443138-56-4
DCC4622 Sbc040

Novel cAMP-independent potentiator of CFTR, synergistically restoring CFTR function

DCC4623 Sbc219

Novel cAMP-independent potentiator of CFTR, synergistically restoring CFTR function

DCC4624 Sbfi-am

Membrane-permeant, fluorescent, selective Na+ indicator dye

129423-53-6
DCC4625 Sbi-0061869

Novel potentiator of metabotropic glutamate receptors for use against neurological and psychiatric disorders

853760-12-0
DCC4626 Sbi-0069332

Novel potentiator of metabotropic glutamate receptors for use against neurological and psychiatric disorders

853760-14-2
DCC4627 Sbi-183

Novel inhibitor of Quiescin Sulfhydryl Oxidase 1 (QSOX1), suppresses tumor cell growth in a Matrigel-based spheroid assay and inhibits invasion in a modified Boyden chamber, but does not affect viability of non-malignant cells

DCC4628 Sbi4211

Inhibitor of S100B which selectively kills melanoma; Amoebicidal diamidine

94345-47-8
DCC4629 Sbp-0636457

Novel Smac mimetic, demonstrating potent cell-killing effects in several subtypes of breast, ovarian, and prostate cancer cell lines but only when the DR ligand TRAIL or another such apoptosis inducer is co-administered

1422180-49-1
DCC4630 Sc-2001

Novel obatoclax derivative, inducing apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation

1383727-17-0
DCC4631 Sc-203885

Potent inhibitor of checkpoint kinase 2 (Chk2)

724708-21-8
DCC4632 Sc-44463

Matrix metalloproteinase (MMP) inhibitor, also acting as a collagenase inhibitor

104408-38-0
DCC4633 Sc-53228

Second-generation leukotriene B4 receptor antagonist

153633-01-3
DCC4634 Sc-558

Selective COX-2 inhibitor

845674-84-2
DCC4635 Sc-68376

Potent and selective inhibitor of p38 MAP kinase

318480-82-9
DCC4636 Sc-75416

Novel selective COX-2 inhibitor

215122-74-0
DCC4637 Scacer1

Novel photoswitchable substrate for sphingomyelin synthase 2 (SMS2), enabling optical control of apoptosis and being ready for azide-alkyne click chemistry

DCC4638 Scacer2

Novel photoswitchable substrate for sphingomyelin synthase 2 (SMS2), enabling optical control of apoptosis and being ready for azide-alkyne click chemistry

DCC4639 Scalaradial

Natural Potent Inhibitor of Transient Receptor Potential Melastatin 2 (TRPM2) Ion Channels

53527-28-9
DCC4640 Sch-202596

Natural selective non-peptide antagonist for the receptor GAL-1

196615-89-1
DCC4641 Sch2-1-20

Novel Inhibitor of the virus fusion to its cell receptor, targeting SARS-CoV-2 spike protein HR1

DCC4642 Sch2-1-27

Novel Inhibitor of the virus fusion to its cell receptor, targeting SARS-CoV-2 spike protein HR1

DCC4643 Sch-23982

Precursor for radioiosotopically labelled R(+)-SCH-23390

99234-87-4
DCC4644 Sch-23985

D1 dopamine receptor antagonist

129666-34-8
DCC4645 Sch-351591

Novel, orally active phosphodiesterase 4 (PDE4) inhibitor

444659-43-2
DCC4646 Sch-43478

Non-​nucleoside antiviral agent, having potent and selective activity against herpes simplex virus type 2 (HSV-​2)

112446-99-8
DCC4647 Sch-51866

Potent and selective PDE1 and PDE5 inhibitor

167298-74-0
DCC4648 Sch-538415

Novel Acyl_carrier_protein_synthase>acyl carrier protein synthase inhibitor; Inhibitor of growth of the bacteria Streptococcus_pneumoniae>Streptococcus pneumoniae and Neisseria_gonorrhoeae>Neisseria gonorrhoeae

637772-75-9
DCC4649 Sch-53870

Inhibitor of p21-hRas nucleotide exchange in vitro

188480-50-4
DCC4650 sch-79687

Novel histamine H3-receptor antagonist

224585-45-9
DCC4651 Sch-900822

Novel potent and selective glucagon receptor antagonist

1220894-09-6
DCC4652 Schembl12616233

Novel inhibitor of SARS-CoV-2 main protease (MPro)

910644-11-0
DCC4653 Schembl1548848

Novel inhibitor of vanilloid receptor subtype 1 (VR1)

DCC4654 Schembl15939407

Novel Lysine-Specific Demethylase 1 (LSD1) Inhibitor (IC50: 20nM)

DCC4655 Schembl18320671

Novel glucose transport inhibitor

DCC4656 Schembl18616095

Novel inhibitor of SARS-CoV-2 main protease (MPro)

DCC4657 Schembl20148701

Novel inhibitor of SARS-CoV-2 main protease (MPro)

DCC4658 scio-469 Hydrochloride

Selective, ATP-competitive p38

309915-12-6
DCC4659 Scq-14d

Novel Inhibitor of p53-Murine Double Minute 2 (MDM2) Interaction and Histone Deacetylases (HDACs) with the IC50 values of 140, 910 and 17.5 nmol/L against MDM2, HDAC1, and HDAC6, respectively, showing the tumor growth inhibition (TGI) in the A549 xenograf

DCC4660 Scr1693

Novel dual acetylcholinesterase inhibitor (AChEI) and a calcium channel blocker (CCB)

1442559-20-7
DCC4661 Scr-4026

Novel inhibitor of nNOS-PSD-95 interaction, exhibiting neuroprotective activities in NMDA-induced or Oxygen and glucose deprivation (OGD)-induced neuronal damage in primary cortical neurons cultures, and ameliorating focal cerebral ischemic damage in rats

DCC4662 Scriptene

NRTI-drug pair of zidovudine (AZT)-didanosine (ddI), being highly cytotoxic and mutagenic

121135-53-3
DCC4663 S-cw3554

Novel irriversible selective PDI inhibitor, selectively labeling protein disulfide isomerase and inhibiting its enzymatic activity, showing unique cytotoxicity in cells derived from multiple myeloma

DCC4664 Sd2590 Hydrochloride

Potent inhibitor of MMP-2, -3, -9, -8, -13, and -14

226395-93-3
DCC4665 Sdz 205-557 Hydrochloride

Selective, surmountable antagonist for 5-HT4 receptors

137196-67-9
DCC4666 Sdz 90-215

Novel inhibitor of the Golgi complex (Vrg4); Antifungal

129816-38-2
DCC4667 Sdz Mrl 953

Novel immunostimulatory monosaccharidic lipid A analog, down-regulating TNF-alpha and IL-6 production and priming secretion of G-CSF and IL-1 beta

123136-61-8
DCC4668 Sdz Ser 082 Fumarate

Selective 5-HT2B/2C receptor antagonist

141474-54-6
DCC4669 sdz-285604

Novel inhibitor of sterol 14a-demethylases (CYP51)

1033846-45-5
DCC4670 Sdz-lap-977

Potent antiproliferative agent, binding to the “colchicine binding site” on tubulin and inhibiting tubulin polymerization in vitro

150779-71-8
DCC4671 sdz-nkt343

Highly selective human tachykinin NK1 receptor antagonist

180046-99-5
DCC4672 Secologanate

Natural plant growth inhibitor

22864-93-3
DCC4673 Seco-rapamycin Ethyl Ester

Novel open-ring metabolite of rapamycin derivative

DCC4674 Securinine Mononitrate

Antagonist of gamma-aminobutyric acid A (GABA A ) receptor and cholinergic agent

7104-26-9
DCC4675 Seh/ache Inhibitor 12c

Novel Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease

DCC4676 Seh-in-12

Novel potent inhibitor of the enzyme soluble epoxide hydrolase (sEH)

1883803-09-5
DCC4677 Sempai

Novel AkaLumine analog, acting asa NIR emission luciferin with the enhanced solubility in water

DCC4678 Sen205a

Novel S100B inhibitor

958712-85-1
DCC4679 Sen461

Novel Wnt inhibitor/Axin stabilizer

1287727-28-9
DCC4680 Sen-826

Novel potent antagonist of the Hedgehog pathway

1160833-51-1
DCC4681 Senp1-in-8e

Sentrin-specific protease 1 (SENP1) inhibitor

DCC4682 Se-nsaid-8

Novel selenium-nonsteroidal anti-inflammatory drug (Se-NSAID), inhibiting colorectal cancer (CRC) growth via the inhibition of the cell cycle in G1 and G2/M phases and reduces the cell cycle markers like cyclin E1 and B1 in a dose dependent manner

DCC4683 Sephin1 Hydrochloride

Selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A) that prolong the benefit of eIF2α phosphorylation, thereby protecting cells from proteostatic defects

32597-86-7
DCC4684 Ser@tpp@cur

Novel mitochondrial KIM-1 receptor modulator to be specifically internalized by renal tubular epithelial cells via KIM-1 receptor-mediated endocytosis and then actively distributed in mitochondria under the effect of TPP, effectively ameliorating injured

DCC4685 Sert Inhibitor 69419

Novel serotonin reuptake inhibitor

305374-42-9
DCC4686 Sertaconazole

Cytochrome P450 14α-demethylase inhibitor, also acting as a BuChE-IDO1 inhibitor

99592-32-2
DCC4687 Setastine

Highly selective H1 receptor antagonist

64294-95-7
DCC4688 Sethrrs Inhibitor 36j

The first-in-class triple-site aaRS inhibitor, targeting Salmonella enterica threonyl-tRNA synthetase (SeThrRS) with IC 50 = 19 nM and K d = 35.4 nM

DCC4689 Setin-1

The most potent inhibitor of Set7, inhibiting the KMTase G9a

1313802-67-3
DCC4690 Trichomonacid

Novel inhibitor of Mycobacterium marinum MelF (Rv1936), exhibiting bacteriostatic/bactericidal activity against M. marinum and M. tuberculosis in vitro

7195-14-4
DCC4691 Seviteronel

Novel potent CYP17 lyase inhibitor, inhibiting androgen production without mineralocorticoid excess or cortisol depletion

1610537-15-9
DCC4692 sew05920

Novel telomerase inhibitor

260392-16-3
DCC4693 Sew-05929

The First potent SecA inhibitor

260392-25-4
DCC4694 Sf-1-087

Potent and selective STAT5 inhibitor

DCC4695 Sf-22 (npy Y2 Antagonist)

Potent, selective, and highly brain-penetrant NPY Y2 receptor antagonist

824981-55-7
DCC4696 Sf2535

Novel dual inhibitor of BRD4 and PI3K, inhibiting BRD4, PI3Kα, PI3Kδ, and PI3Kγ with IC 50 values of 277, 714, 27, and 1170 nM, respectively

DCC4697 Sfom-0046

Novel anticancer agent, arresting cell cycle in S-phase and causes DNA replication stress leading to the phosphorylation of H2AX into gamma-H2AX

1383607-61-1
DCC4698 Sfrp-1 Inhibitor-1

Cell-permeable antagonist of secreted frizzled related protein-1(sFRP-1), inhibiting Wnt-3/frizzled interaction and restoring cellular response to Wnt-3 stimulation

302804-57-5
DCC4699 Sfti-1

Highly Potent and Selective Plasmin Inhibitor, Attenuating Fibrinolysis in Plasma

DCC4700 Sgc-camkk2-1

Novel probe for CAMKK2/CAMKK1

DCC4701 Sgc-clk-1

Novel probe for CLK1, CLK2, and CLK4

DCC4702 Sgc-gak-1n

Negative control for SGC-GAK-1 (GLXC-31266)

DCC4703 Sge201

Novel potent allosteric modulator of N-methyl-D-aspartate receptors (NMDAR)

35882-85-0
DCC4704 Sgi-10067

PKM2 activator, potently inhibiting proliferation of cancer cells in media lacking serine

DCC4705 Sgi-9380

PKM2 activator, potently inhibiting proliferation of cancer cells in media lacking serine

DCC4706 Sgk1 Inhibitor 17a

Novel highly selective SGK1 inhibitor with a highly optimized profile suitable for oral dosing as a potentially disease-modifying agent for osteoarthritis

DCC4707 Sglt1/2-in-8

Novel Potent SGLT1/2 Dual Inhibitor

DCC4708 Sgx393

Novel inhibitor of the CML mutant Bcr-AblT315I, preempting in vitro resistance when combined with nilotinib or dasatinib.

1030610-86-6
DCC4709 Sh-053-r-ch3-2’f

Selective agonist of GABA A receptors α5 subunit

872874-14-1
DCC4710 Sh-053-s-ch3-2'f

Potent and selective agonist of GABAA receptors α5 subunit

872874-00-5
DCC4711 Sh-11037

Novel potent sEH inhibitor, effectively blocking key angiogenic properties of human retinal endothelial cells (HRECs), inhibiting choroidal sprouting and significantly suppressing CNV lesion volume

DCC4712 Sh-11052

Novel inhibitor of endothelial cell growth

DCC4713 Sh-2251

Novel selective inhibitor of the generation of IL-5-producing Th2 cells and induction of active histone modifications at the IL5 gene locus during Th2 cell differentiation

DCC4714 Sha 14-1

Stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypassing drug resistances and synergizing cancer therapies in human leukemia cell

1033753-87-5
DCC4715 She-196

First in Class Hypoglycemic Agent with Extra-Strong Action, increasing insulin sensitivity, improving glucose tolerance, reducing fasted insulin level and insulin sensitivity, decreasing total body and interscapular fat mass and also increasing the activi

DCC4716 Sherpa Bmi-135

Novel Selective Human ER Partial Agonist (ShERPA)

DCC4717 Sheta2

Selective inhibitor of cancer cell growth, exerting chemoprevention activity without evidence of toxicity

361483-66-1
DCC4718 Sh-i-14

Novel Inhibitor of Phospho-STAT3 Through Induction of Protein Tyrosine Phosphatase PTPN6

DCC4719 Shield-2

Novel potent stabilizing ligand for FKBP-derived destabilizing domains

1013621-70-9
DCC4720 Ship-2a

Cystathione gamma lyase (CSE) inhibitor, inhibiting H2S production and L-cysteine-induced relaxation of rat aortic rings ex vivo

1250186-20-9
DCC4721 Showdomycin

Antineoplastic antibiotic

16755-07-0
DCC4722 Shp2 Inhibitor C21

Inhibitor of shp2 protein tyrosine phosphatase (PTP)

293327-21-6
DCC4723 Shr0687

Highly Potent and Peripheral Nervous System-Restricted KOR Agonist

DCC4724 Sibopirdine

Novel cognitive enhancer; Nootropic agent

122955-18-4
DCC4725 Sid-24784551

Novel direct HIV-1 Nef antagonist with antiretroviral activity

332420-75-4
DCC4726 Sid-7977382

Novel Complement Factor C1 Inhibitor

349114-29-0
DCC4727 Silagaba132

Silicon-Containing GABA Derivative, Treating Neuropathic Pain without Central-Nervous-System-Related Side Effects

1607006-78-9
DCC4728 Silagaba161

Silicon-Containing GABA Derivative, Treating Neuropathic Pain without Central-Nervous-System-Related Side Effects

1607006-79-0
DCC4729 Sila-ibuprofen

Novel COX-I and COX-II inhibitor with four times higher solubility in physiological media and a lower melting enthalpy than ibuprofen

DCC4730 Simfibrate

Peroxisome proliferator

14929-11-4
DCC4731 Sinapine Sulfate

Antioxidant and antimicrobial agent, counteracting mitochondrial oxidative stress in cardiomyocytes

6484-83-9
DCC4732 Sipi-6360

Novel D2/5-HT2A Receptor Dual Antagonist

1401333-14-9
DCC4733 Sipi-7623

Novel farnesoid X receptor antagonist

DCC4734 Sirt1-a2

Novel SIRT1 Activator

304448-98-4
DCC4735 Sirt1-enhancer-a03

First-in-class apolipoprotein E4 (ApoE4)-targeted sirtuin1 (SirT1) enhancer, normalizing sirtuin 1 levels and improving cognition in an Alzheimer's disease mouse model

60719-82-6
DCC4736 Sirt1-i5

Novel SIRT1 Inhibitor, showing potent effect on prostate cancer cell line

601502-36-7
DCC4737 Sirt1-in-4bb

Novel SIRT1 inhibitor, inducing apoptosis in HCT116 human colon carcinoma cells partially by activating p53

DCC4738 Sirt2-in-6f

Potent and selective inhibitor of SIRT2

DCC4739 Sirt3 Inhibitor P6

Novel selective SIRT3 inhibitor, exhibiting SIRT3 inhibitory selectivity with IC50 value of 7.2 µM over SIRT1 (32.6 µM) and SIRT2 (33.5 µM), showing potent inhibitory activity against a group of MLLr leukemic cell lines

DCC4740 Sir-tz

Novel in situ tetrazine ligation reactive silicon-rhodamine dye

DCC4741 Sitafloxacin

Potent broad spectrm fluoroquinolone antibiotic

127254-12-0
DCC4742 Sitafloxacin Monohydrate

Fluoroquinolone antibiotic, acting as antibacterial, antineoplastic, anti-Infective agents, Inhibiting DNA-gyrase and topoisomerase

163253-37-0
DCC4743 Si-w052

Novel inhibitor of lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-α and interleukin (IL)-6 on microglia, exhibiting anti-inflammatory activity through ER-stress-mediated autophagy, significantly inducing the conversion ratio of LC3 II/I and

DCC4744 Sj1008066

Novel inhibitor of MAGE-A11 with robust activity in TR-FRET for disrupting MAGE-A11:PCF11 interactionm being cell permeable and having improved activity in the TR-FRET assay (IC50 0.13 µM)

DCC4745 Sj3366

Unique and highly potent nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1), also inhibiting HIV-2

195720-26-4
DCC4746 Sj521054

Novel inhibitor of MAGE-A11 with robust activity in TR-FRET for disrupting MAGE-A11:PCF11 interaction (IC50 0.40 μM)

DCC4747 Sj572710

Novel Inhibitor of the Disordered Protein, p27(Kip1)

328021-97-2
DCC4748 Sj-bis

Novel selective MDMX antagonist

DCC4749 Sjf-0628

Novel BRAF-targeting PROTAC, inducing efficient and potent degradation of mutant BRAF but sparing BRAFWT, inhibiting cell growth in mutant-BRAF driven cancer cells

2413035-41-1
DCC4750 Sjf-1521

Novel selective EGFR degrader

2230821-40-4
DCC4751 Sjf-1528

Novel potent EGFR degrader, being capable of penetrating the cell membrane, also degrading an exon-20 insertion mutant form of EGFR (ASV duplication)

2230821-38-0
DCC4752 Sjg-136

Novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity

232931-57-6
DCC4753 Sjp-l-5

Novel inhibitor of HIV-1 infection by blocking viral DNA nuclear entry

1286237-83-9
DCC4754 Sk-575

Highly potent and efficacious proteolysis targeting chimera (PROTAC) degrader of PARP1 for treating cancers, potently inhibiting the growth of cancer cells bearing BRCA1/2 mutations and inducing potent and specific degradation of PARP1 in various human ca

DCC4755 Skf64346 Hydrochloride

Inhibitor of Aβ self-aggregation

57664-06-9
DCC4756 Skf-80723 Hydrobromide

Dopamine D1 receptor agonist

71636-62-9
DCC4757 Skf-99101h

Selective, brain penetrant 5-HT(1B/D) receptor agonist

172378-03-9
DCC4758 Ski-349

Novel dual-targeted inhibitor of sphingosine kinase and microtubule polymerization

727686-80-8
DCC4759 Ski-417616

Potent inhibitor of Dengue viruses (DENV), displaying activities against all four serotypes of DENV, as well as to a related flavivirus, West Nile virus (WNV), and an alphavirus, Sindbis virus (SINV)

DCC4760 S-kkwk

Potent influenza A virus (IAV) entry inhibitor, targeting a conserved region of hemagglutinin

DCC4761 sklb023

Novel inhibitor of NF

1266715-49-4
DCC4762 Sklb028

Millepachine analog, inhibiting tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin

DCC4763 Sklb050

Biological Active Reagents

DCC4764 Sklb-163

Potent anticancer agent, downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK

1255099-06-9
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