Cat. No. | Product name | CAS No. |
DC8601 |
IAA-94
IAA-94 is an indanyloxyacetic acid blocker of epithelial chloride channels. |
54197-31-8 |
DC12105 |
IACS-10759 Hydrochloride
IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation (OXPHOS). |
1807523-99-4 |
DC21131 |
IACS-4619
IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.2 nM. |
1884209-98-6 |
DC21132 |
IACS-4759
IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.6 nM. |
1884209-99-7 |
DC23352 |
IACS-7e
IACS-7e is a potent TRIM24 bromodomain inhibitor with IC50 of 217.8 nM (TRIM24 ligand displacement).. |
1800477-13-7 |
DC23361 |
IACS-9571
IACS-9571 is a potent, selective dual TRIM24-BRPF1 bromodomain inhibitor with Kd of 31 and 14 nM, respectively. |
1800477-30-8 |
DC23546 |
IAXO-102
IAXO-102 is a novel selective TLR4 antagonist, negatively regulates non-hematopoietic TLR4 signalling and inhibits experimental AAA development. |
1115270-63-7 |
DC21905 |
IBET151-VHL-PROTAC
IBET151-VHL-PROTAC is a novel PROTAC.. |
|
DC12341 |
Ibiglustat succinate (Venglustat (succinate); GZ/SAR402671 (succinate))
Ibiglustat (succinate) is a selective inhibitor of glucosylceramide synthase. |
1629063-78-0 |
DC7635 |
IB-MECA
Featured
IB-MECA is a potent and selective A3 adenosine receptor agonist (Ki values are 1.1, 54 and 56 nM for A3, A1 and A2A receptors respectively). |
152918-18-8 |
DC21134 |
IBR2
IBR2 is a novel small molecule RAD51 inhibitor that specifically binds to RAD51 and disrupts the BRC repeats of BRCA2/RAD51 interaction with IC50 of 0.11 uM. |
313526-24-8 |
DC22112 |
IBS003031
IBS003031 (IBS-003031) is a novel chemical Yes-associated protein 1 (YAP1) activator, up-regulates H2B-mCherry expression at 1 and 3 uM in mCherry signal based reporter assays. |
381177-81-7 |
DC8573 |
Ibufenac
Ibufenac is an analog of the NSAID ibuprofen that inhibits COX-1 and -2 activity with IC50 values of 17.4 and 13.1 µM, respectively. |
1553-60-2 |
DC20411 |
Ibulocydine
Ibulocydine is the prodrug of CDK inhibitor BMK-Y101, inhibits CDK7 and CDK9 with IC50 of 530 nM and 85 nM in kinase assays, respectively. |
1314096-68-8 |
DC21135 |
IC 86621
Featured
IC 86621 is a potent DNA-PK inhibitor with IC50 of 135 nM, also inhibits p110β (IC50=135 nM), less potent for p110α/γ/δ (IC50=880-1,400 nM). |
404009-40-1 |
DC21136 |
IC 87361
IC 87361 is a potent and selective DNA-PK inhibitor with IC50 of 34 nM, shows >50-fold selectivity over p110β. |
404011-02-5 |
DC23271 |
IC-9564
IC-9564 (AIDS033640) is a betulinic acid derivative and potent HIV entry inhibitor that blocks HIV-1 envelope-mediated membrane fusion with IC90 of 0.22 uM for NL4-3 strain. |
174847-98-4 |
DC10983 |
ICA-1(ICA-1T)
Featured
ICA-1(ICA-1T)is a potent, specific inhibitor of Protein Kinase C-iota (PKC-ι) with IC50 of 0.1 uM, does not inhibit PKC-ζ, the closely related atypical PKC family member. |
742038-81-9 |
DC22114 |
ICA135
ICA135 (ICA-135, ICA 135) is a broad-spectrum inhibitor against human enteroviruses that inhibits Coxsackievirus A10 (CV-A10) replication in RD cells with IC50 of 1.446 uM. |
825601-94-3 |
DC3115 |
ICI-118551
Featured
ICI-118,551 is a selective beta-2 (β2) adrenergic receptor antagonist.ICI binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor. |
72795-01-8 |
DC7427 |
Icotinib
Icotinib(BPI-2009) is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R). |
610798-31-7 |
DC21139 |
iCRT-5
iCRT-5 is a selective, cell-permeable β-catenin responsive transcription (CRT) inhibitor with IC50 of 18 nM. |
18623-44-4 |