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Cat. No. Product name CAS No.
DC8909 Maribavir Featured

Maribavir(GW257406X; BW1263W94; 1263W94) inhibits HCMV replication is by inhibition of an HCMV encoded protein kinase enzyme called UL97 or pUL97.

176161-24-3
DC8031 Marimastat

Marimastat is a broad spectrum MMP inhibitor and selective TACE inhibitor

154039-60-8
DC10639 Marinopyrrole A (Maritoclax)

Marinopyrrole A (Maritoclax) is a selective Mcl-1 antagonist. It binds to Mcl-1, but not Bcl-XL, and targets Mcl-1 for proteasomal degradation. Maritoclax disrupts the interaction between Bim and Mcl-1 with an IC50 of 10.1 μM.

1227962-62-0
DC20883 Maropitant citrate

Maropitant citrate (Cerenia) is a selective neurokinin 1 receptor (NK1) antagonist for prevention of vomiting due to motion sickness in dogs..

862543-54-2
DC9519 Maropitant

Maropitant is a neurokinin (NK1) receptor antagonist.

147116-67-4
DC20443 MARPIN

MARPIN is a novel ATR-Chk1 pathway inhibitor that inhibits hydroxyurea (HU)-induced phosphorylation of Ser345 on Chk1 with IC50 of 7.7 uM.

848675-17-2
DC7460 Masitinib Featured

Masitinib is a broad coronavirus 3CL inhibitor that effectively blocks replication of SARS-CoV-2. Science 20 Jul 2021: eabg5827 DOI: 10.1126/science.abg5827

790299-79-5
DC11236 MB-07811 (VK-2809) Featured

MB-07811 (VK-2809) is an orally bioavailable, liver-targeted prodrug of MB07344, which is a thyroid hormone receptor-beta agonist (TRβ) agonist, efficiently converted to MB07344 by liver microsomes in vivo.

852948-13-1
DC10958 MB710

MB710 is a small-molecule p53 mutant Y220C stabilizer, binds tightly to the Y220C pocket and stabilizes p53-Y220C in vitro..

2230044-57-0
DC10957 MB725 Featured

MB725 is a small-molecule p53 mutant Y220C stabilizer, induces selective viability reduction in several p53-Y220C cancer cell lines (Huh7 cell IC50=10 uM).

2230058-99-6
DC12094 MBQ-167

MBQ-167 is a dual Rac/Cdc42 inhibitor, with IC50s of 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively.

2097938-73-1
DC21270 MC-1575

MC-1575 is a potent and selective class IIa HDAC inhibitor with IC50 of 440 nM for maize HD1-A, displays >70-fold selectivity over HD1-B.

DC23370 MC2884

MC2884 is a novel hybrid, dual HAT/EZH2 inhibitor with IC50 of 3.27, 8.35 and 4.56 uM for CBP, KAT5 and p300, respectively.

330657-42-6
DC11358 CPP32 Fluorogenic Substrate III

Mca-DEVDAPK(Dnp)-OH is a substrate for caspase-3.

189696-20-6
DC11338 MMP-2/MMP-7 Fluorogenic Substrate Control Featured

Mca-PL is a fluorogenic peptide that has been used as a building block in the synthesis of Mca-PLGL-Dpa-AR-NH2, a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-7.

140430-55-3
DC8550 MCB-613 Featured

MCB-613 is a novel and potent stimulator of p160 steroid receptor coactivators (SRCs). It is a Pan-SRCs stimulator.

1162656-22-5
DC23706 Netoglitazone(MCC 555) Featured

Netoglitazone, also known as isaglitazone and MCC-555, is an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic activity. Netoglitazone exerts both peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist activity. Netoglitazone decreases bone formation and increases marrow adipocyte formation in vivo.MCC 555 (Isaglitazone.

161600-01-7
DC26085 MCL0129

MCL0129 is a selective, potent melanocortin-4 receptor (MC4R) antagonist with Ki of 7.9 nM, without affinity for MC1 and MC3.

768357-45-5
DC22643 Mcl1-IN-2

Mcl1-IN-2 is an Mcl-1 inhibitor without a reported IC50 value..

292057-76-2
DC20444 Mcl-1-Puma inhibitor 8

Mcl-1-Puma inhibitor 8 is a small-molecule dual-acting compound that targets the apoptotic Mcl-1-PUMA interface with Ki of 0.3 uM (Mcl-1, FPA), reduces multiple cancer cells and inhibits PUMA-mediated apoptosis.

678158-55-9
DC10353 MCOPPB triHydrochloride

MCOPPB 3Hcl is a nociceptin receptor agonist with pKi of 10.07; weaker activity at other opioid receptors.

1108147-88-1
DC23820 MCP110 Featured

MCP110 is a potent Ras/Raf-1 interaction inhibitor.

521310-51-0
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