Cat. No. | Product name | CAS No. |
DC23711 |
MRL20
MRL20 is a novel synthetic PPARγ ligand and orthosteric agonist with canonical LBP binding affinity of 2 nM. |
393794-32-6 |
DC11047 |
MRL871
Featured
MRL-871 (MRL871) is a potent, selective inhibitor of RORγt via allosteric inverse agonism, inhibits coactivator binding with IC50 of 7 nM; significantly reduces the IL17a mRNA levels in EL4 murine lymphoblast cell line at 10 uM. |
1392809-08-3 |
DC20220 |
MRS-1845
Featured
MRS 1845 is a potent calcium channel protein inhibitor and inhibits capacitative Ca2+ influx in HL-60 cells (IC50 = 1.7 mM). |
544478-19-5 |
DC23483 |
MRS 2179
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM. |
101204-49-3 |
DC23471 |
MRS 2179 tetrasodium
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM. |
1454889-37-2 |
DC23733 |
MRS 2481
MRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity. |
859724-30-4 |
DC23740 |
MRS 2485
MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity.. |
859724-34-8 |
DC12260 |
MRS1177
MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM. |
183721-13-3 |
DC12258 |
MRS1186
MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM. |
183721-03-1 |
DC12803 |
MRS1754
Featured
MRS1754 is a selective adenosine A2B receptor antagonist (Ki values are 1.97, 16.8, 403, 503, 570 and 612 nM for hA2B, rA1, hA1, hA2A, hA3 and rA2A receptors respectively). |
264622-58-4 |
DC7203 |
MRS 2578
Featured
MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors. |
711019-86-2 |
DC22164 |
MRS4458
MRS4458 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 169 nM, does not display extensive off-target interactions with biogenic amine receptors.. |
|
DC22165 |
MRS4478
MRS4478 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 269 nM, does not display extensive off-target interactions with biogenic amine receptors.. |
|
DC21344 |
MRT 199665
MRT 199665 is a potent salt-inducible kinases (SIKs) inhibitor with IC50 of 110, 12, 43 nM for SIK1,2,3 respectively. |
1456858-57-3 |
DC10635 |
MRT67307 HCl
Featured
MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. |
1190378-57-4 |
DC23898 |
MRT-83 hydrochloride
MRT-83 hydrochloride is a potent Smoothened antagonist that blocks Hedgehog (Hh) signaling in various assays with IC50 of 10 nM. |
1359944-60-7 |
DC12288 |
MRT-83
MRT-83 is a potent antagonist of Smo, with an IC50 in the nanomolar range. |
1263131-92-5 |
DC12651 |
MRTX1257
Featured
MRTX1257 (MRTX-1257, MRTX 1257) is a potent, selective, covalent and irreversible inhibitor of KRAS G12C, inhibits KRAS dependent ERK-phosphorylation in the H358 cell with IC50 of 0.9 nM. |
2206736-04-9 |
DC21346 |
MS012
MS012 is a potent and selective inhibitor of G9a-Like Protein (GLP) lysine methyltransferase with IC50 of 7 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases.. |
2089617-83-2 |
DC21347 |
MS0124
MS-0124 is a potent and selective inhibitor of G9a-like Protein (GLP) lysine methyltransferase with IC50 of 13 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases.. |
1197196-63-6 |
DC21348 |
MS2734
Featured
MS2734 is a bisubstrate Nicotinamide N-methyltransferase (NNMT) with IC50 of 14 uM, Kd of 2.7 uM.. |
|
DC8574 |
MS37452
Featured
MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM). |
423748-02-1 |