Cat. No. | Product name | CAS No. |
DC23016 |
Nexinhib 20
Nexinhib 20 is a novel small molecule neutrophil exocytosis inhibitor (IC50=0.33 uM) that specifically inhibits Rab27a-JFC1 binding (IC50=2.6 uM) but does not interfere with the interaction of other Rab GTPases and effectors. |
1162656-24-7 |
DC12176 |
NFAT Transcription Factor Regulator
Featured
NFAT Transcription Factor Regulator is an IL-2 synthesis inhibitor with an IC50 of 182 nM. |
245747-71-1 |
DC11171 |
NFEPP
NFEPP is a novel potent, selective pH-dependent μ-opioid receptor (MOR) agonist with a low pKa, shows significantly lower affinity compared with fentanyl at pH 7.4. |
1422952-82-6 |
DC23081 |
NFPS
NFPS (ALX-5407) is a potent, selective GlyT1 inhibitor with IC50 of 2.8 and 9.8 nM for hGlyT1 and rGlyT1 respectively, >5,000-fold selectivity over rGlyT2. |
405225-21-0 |
DC21380 |
NGD-4715
NGD-4715 is a potent, selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1), has anxiolytic, antidepressant and anorectic effects.. |
476322-70-0 |
DC11200 |
NGI-1 derivative C-19
NGI-1 derivative C-19 is a specific, small-molecule inhibitor of oligosaccharyltransferase (OST) catalytic subunit STT3B, without effect on STT3A. |
924471-88-5 |
DC8525 |
NIBR-17
Featured
NIBR-17 is a pan class I PI3K inhibitor with IC50 values of 1, 9.2, 9 and 20 nM respectively for PI3Kapha - delta. |
944396-88-7 |
DC21742 |
NIBR-3049
NIBR-3049 (TCS-21311) is a potent, highly selective JAK3 inhibitor with IC50 of 8 nM, displays >100-fold selectivity over JAK1, JAK2 and TYK2, also inhibits PKCα, PKCθ, and GSK3β with IC50 of 13, 68, and 3 nM, respectively.. |
1260181-14-3 |
DC25090 |
Nicardipine
Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.. |
55985-32-5 |
DC21243 |
Nidufexor(LMB-763)
Featured
Nidufexor (LMB763, LMB-763) is a novel potent farnesoid X receptor (FXR) agonist for the treatment of non-alcoholic steatohepatitis (NASH) and hepatobiliary disorders. |
1773489-72-7 |
DC12297 |
Nigakinone
Nigakinone is one of the most abundant alkaloids responsible for the major pharmacological activities of Kumu. |
18110-86-6 |
DC10927 |
NIK inhibitor 4f(NIK SMI1)
Featured
NIK SMI1 is a potent, selective small molecule inhibitor of NF-κB inducing kinase (NIK) with Ki of 230±170 pM; only inhibits 3 out of 222 off-target kinases (KHS1, LRRK2, and PKD1) with >75% inhibition at 1 uM; potently inhibits anti-LTβR-induced nuclear p52 levels in anti-LTβR-stimulated HeLa cells, with no effect on canonical signaling; inhibits BAFF and CD40 signaling, suppresses immune responses in vivo; suppresses disease biomarkers and improves survival and renal function in NZB/W F1 mice. |
1660114-31-7 |
DC4192 |
Nilutamide
Nilutamide is an antiandrogen medication used in the treatment of advanced stage prostate cancer. |
63612-50-0 |
DC9379 |
Nilvadipine
Nilvadipine(FR34235) is a calcium channel blocker for treatment of hypertension. |
75530-68-6 |
DCAPI1251 |
Nitazoxanide (Alinia, Annita)
Featured
Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM). |
55981-09-4 |
DC7791 |
NITD 609
NITD 609 is a novel and potent drug candidate for the treatment of uncomplicated malaria |
1193314-23-6 |
DC21383 |
NITD-304
NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv. |
1473450-60-0 |
DC21384 |
NITD-349
NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv. |
1473450-62-2 |
DC21385 |
NITD-564
NITD-564 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.59 uM, exhibits MIC50 of 160 nM against Mtb. |
1614262-75-7 |
DC21386 |
NITD-916
NITD-916 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.57 uM, exhibits MIC50 of 50 nM against Mtb. |
1614262-83-7 |
DC21388 |
NJK14047
NJK14047 is a novel potent, selective p38 MAPK inhibitor with IC50 of 27 nM against p38α, suppresses RSV and influenza A virus replication by inhibiting virus-induced p38 MAPK activation. |
1800576-41-3 |
DC20916 |
NKH 477 hydrochloride
Featured
NKH 477 hydrochloride (Colforsin dapropate) is a water-soluble analog of Forskolin and a potent activator of adenylyl cyclase, shows some selectivity for cardiac (type V) adenylyl cyclase. |
138605-00-2 |