Cat. No. | Product name | CAS No. |
DC22615 |
Rosuvastatin
A potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with IC50 of 11 nM. |
287714-41-4 |
DC20318 |
BCML
A potent, competitive inhibitor of quinine-activated bitter taste receptor T2R4 with IC50 of 59 nM.. |
113231-05-3 |
DC11767 |
IJ-5
A potent, covalent inhibitor of ubiquitin-conjugating enzyme UbcH5 with Kd of 5.189 uM, 3.578 uM, and 2.577 uM for UbcH5a, UbcH5b, and UbcH5c, respectively. |
68776-47-6 |
DC11624 |
WIN-18446
A potent, covalent, orally active ALDH1A2 inhibitor with IC50 of 0.3 uM. |
1477-57-2 |
DC20702 |
Ilepatril
A potent, dual ACE-neutral endopeptidase (vasopeptidase) inhibitor with IC50 of 0.053 and 5.0 nM, respectively. |
473289-62-2 |
DC23394 |
Dual BET-Kinase inhibitor 3
A potent, dual BET bromodomain-kinase inhibitor with IC50 of 34, 1.1 and 1.1 nM for BRD4 BD1, JAK2 and FLT-3, respectively. |
1877286-69-5 |
DC20885 |
CGP-74514A
A potent, dual CDC-like kinase (CLK)/CDK inhibitor with IC50 of 148, 111, 104, 382 and 573 nM for CLK1, CLK2, CLK4, CDK1 and CDK4, respectively.. |
190653-73-7 |
DC24059 |
PI-103 hydrochloride
Featured
A potent, dual class I PI3K/mTOR inhibitor with IC50 of 2/3/3/15/ for p110α/β/δ/γ, respectively. |
371935-79-4 |
DC11837 |
RO-5963
Featured
RO-5963 is an inhibitor of the interaction of both MDM2 and MDMX with p53. |
1416663-77-8 |
DC21562 |
Pz-1
A potent, dual pan-RET/VEGFR2 kinase inhibitor with IC50s of <1 nM for all RET, RET V804M and VEGFR2. |
1800505-64-9 |
DC20542 |
SA 16
A potent, dual PDK1 and Aurora kinase A inhibitor with IC50 of 416 and 35 nM, respectively. |
1919884-11-9 |
DC22545 |
TG 100572 hydrochloride
A potent, dual receptor tyrosine kinase/Src kinase inhibitor with IC50 of 2-16 nM for VEGFR, FGFR and PDGFR, 0.1-5 nM for Src family. |
867331-64-4 |
DC23967 |
TG 100572
A potent, dual receptor tyrosine kinase/Src kinase inhibitor with IC50 of 2-16 nM for VEGFR, FGFR and PDGFR, 0.1-5 nM for Src family. |
867334-05-2 |
DC20663 |
AMG 511
A potent, efficacious, and orally available pan class I PI3K inhibitor with Ki of 4/6/2/1 nM for PI3Kα/β/δ/γ, respectively. |
253573-53-3 |
DC11976 |
SX-576
A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively. |
1240494-14-7 |
DC11533 |
PH-46A N-Methyl-D-Glucamine salt
A potent, first-in-class, oral small-molecule agent for the treatment of inflammatory bowel diseases.. |
1380445-04-4 |
DC11532 |
PH-46A
A potent, first-in-class, oral small-molecule agent for the treatment of inflammatory bowel diseases.. |
1421332-97-9 |
DC23211 |
SKF 82958
Featured
A potent, full dopamine D1 agonist. |
80751-65-1 |
DC20939 |
NCGC00379308
Featured
A potent, functionally selective TSH receptor (TSHR) positive allosteric modulator with EC50 of 11.6 uM (β-Arr 1 translocation). |
662164-09-2 |
DC23958 |
MRK-016
A potent, functionally selective, CNS-penetrating and orally bioavailable inverse agonist of benzodiazepine site of GABAA α5 receptor with Ki of 0.8-1.5 nM for α1-, α2-, α3-, andα5-containing GABAA receptors. |
342652-67-9 |
DC11903 |
NBUMP
A potent, highly selective 5-HT1A receptor partial agonist with Ki of 0.1 nM, displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively.. |
1348755-27-0 |
DC20599 |
25CN-NBOH
A potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM ([3H]ketanserin). |
1391489-32-9 |