DCC2016 |
Etb067 |
H-89 analog as PKA and AKT1 inhibitor with specificity on no longer inhibiting CAMK2B and neither affecting viability of mice nor causing any detectable tissuedamage at the dose given |
|
DCC2017 |
Etc-131 |
Novel inhibitor of PORCN, inhibiting ß-catenin reporter activity in a dose-dependent manner |
|
DCC2018 |
Ethd-1 |
Cell-impermeant viability indicator, as high-affinity nucleic acid stain that is weakly fluorescent until bound to DNA and emits red fluorescence (excitation/emission maxima ~528/617). |
|
DCC2019 |
Etheofazine |
Novel anticancer agent |
|
DCC2020 |
Ethyl 3-hydroxyhexanoate |
Natural potent antiviral agent, significantly inhibiting coxsackievirus group B (CVB) replication both in vivo and in vitro |
|
DCC2021 |
Ethyl Lipotf |
Novel selective FTO inhibitor |
|
DCC2022 |
Ethylvanillin |
TRPA1 channel agonist |
|
DCC2023 |
Etifoxine |
Activator of β2 and β3 subunit containing channels of the GABAA receptor complex, stimulating the production of GABA(A) active neurosteroids |
|
DCC2024 |
Et-kuq |
Novel enhancer of the religation reaction of human topoisomerase I |
|
DCC2025 |
et-nhp5g |
Partial agonist at the glutamate binding site of the GluN2 subunits |
|
DCC2026 |
Etoxazole |
Pesticide, acting as antibiotics or growth regulators to kill mites and ticks |
|
DCC2027 |
etp-45299 |
Potent and selective inhibitor of Pim 1, inhibiting the phosphorylation of Bad and 4EBP1 in cells and suppresses the proliferation of several non-solid and solid human tumor cell lines. |
|
DCC2028 |
Etx2514 |
Novel broad-spectrum β-lactamase inhibitor |
|
DCC2029 |
Eu1622-14 |
Novel Biased modulator of NMDA receptors, controlling channel opening and ion selectivity |
|
DCC2030 |
Eu1794-4 |
Novel negative allosteric modulator (NAM) of NMDA receptors, reducing both the overall current that flows following receptor activation and the flux of Ca2+ ion relative to monovalent cations |
|
DCC2031 |
Euk-124 |
Scavenger for oxidative species such as peroxynitrite, superoxide, and hydrogen peroxide |
|
DCC2032 |
Evolidine |
The first plant cyclic peptide with antibacterial and antifungal activity |
|
DCC2033 |
Evp-0015962 |
Novel potent gamma-secretase modulator |
|
DCC2034 |
Evt-101 |
Novel GluN2B antagonist, binding at the same GluN1/GluN2B dimer interface as ifenprodil but adopting a remarkably different binding mode involving a distinct subcavity and receptor interactions |
|
DCC2035 |
Evt-201 |
Novel partial positive allosteric GABAA receptor modulator |
|
DCC2036 |
Ew-7203 |
Novel ALK5 inhibitor |
|
DCC2037 |
Ex4-dnp Conjugate 7 |
Novel glucagon-like peptide 1 (GLP-1) receptor agonist, displaying significantly elongated half-lives and improved long-acting antidiabetic activity in the presence of endogenous anti-DNP antibodies |
|
DCC2038 |
Ex-527(r) |
Potent and selective SIRT1 inhibitor |
|
DCC2039 |
Ex-527(s) |
Potent and selective SIRT1 inhibitor |
|
DCC2040 |
Exatecan Mesylate Dihydrate |
Topoisomerase I inhibitor |
|
DCC2041 |
exosensor 517 |
Novel Dual-Analyte Fluorescent Chemosensor for Visualizing Neurotransmitter Exocytosis |
|
DCC2042 |
Ex-tbdps-chc |
Novel potent MCT1 inhibitor, exhibiting good single agent anticancer efficacy properties |
|
DCC2043 |
Ezn-2208 |
Polyethylene glycol conjugate of SN38, acting as a topoisomerase I inhibitor,, exerting significant anti-leukaemia activity, overcoming ABCG2-mediated topotecan resistance |
|
DCC2044 |
F0045(s) |
Novel influenza A hemagglutinin (HA) fusion inhibitor (EC 50 = 1.9 ± 0.3 μM), preventing HA from transitioning to the postfusion state at pH 5.0 |
|
DCC2045 |
F0371-0041 |
Novel antifungal agent against Candida albicans persister cells |
|