| DCC2088 |
Fc11a-2 |
Specific inhibitor of inflammasome assembly, targeting the NLRP3 inflammasome by interfering with the proximity-induced autocleavage of procaspase-1 |
|
| DCC2089 |
Fcpr16 |
Novel phosphodiesterase 4 (PDE4) inhibitor with little emetic potential, blocking MPP+ induced oxidative damage in SH-SY5Y cells and neurons via AMPK-dependent autophagy |
|
| DCC2090 |
Fc-rapa |
Novel rapamycin derivative, targeting polycystic kidneys due to the high expression of the folate receptor (FRα), lacking the extra-renal effects of unconjugated rapamycin, in particular immunosuppressive effects |
|
| DCC2091 |
Feiii-ppix Ligand-18 |
Novel potent antimalarial agent, binding to ferriprotoporphyrin-IX (FeIII-PPIX) (Kd = 33 nM) against chloroquine-resistant and sensitive strains of Plasmodium falciparum |
|
| DCC2092 |
Fenobam |
Potent, selective, noncompetitive glutamate mGluR5 receptor antagonist |
|
| DCC2093 |
Fenoprofen Calcium Dihydrate |
Non-steroidal anti-inflammatory drug, being used for symptomatic relief for rheumatoid arthritis, osteoarthritis, and mild to moderate pain |
|
| DCC2094 |
Fenspiride Hydrochloride |
Non-steroidal antiinflammatory agent |
|
| DCC2095 |
Ferric Maltol |
Novel oral iron therapy agent, being effective in correcting iron deficiency anemia in patients with inflammatory bowel disease |
|
| DCC2096 |
Ferroptosis Inducer |
Novel ferroptosis inducer, killing selected cancer cell lines by harnessing reactive oxygen species (ROS) |
|
| DCC2097 |
Ferroxamine B |
Iron chelator, mediating iron transport in Streptomyces pilosus |
|
| DCC2098 |
Ferulin C |
Natural potent colchicine site binding microtubule-destabilizing agent with anti-proliferation and anti-metastasis activity via PAK1 and p21-mediated signaling in breast cancer cells |
|
| DCC2099 |
Ffa2-agonist-1 |
Selective orthosteric agonist of human FFA2 |
|
| DCC2100 |
Ffa3-agonist-1 |
Selective and moderately potent positive allosteric modular (PAM)-agonist of the FFA3 receptor |
|
| DCC2101 |
Ffa3-antagonist-6 |
Novel PAM-antagonist of the function of C3 at FFA3 |
|
| DCC2102 |
ffn206 |
Novel fluorescent probe as an excellent VMAT2 substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy |
|
| DCC2103 |
Fgf/pdgf/vegf Rtk Inhibitor |
Potent, reversible, ATP-competitive inhibitor against PDGFRβ, FGFR-1, and VEGFR-2 (IC50 = 20, 90, and 240 nM, respectively) and effectively suppresses VEGF-stimulated proliferation of HMVECs (EC50 = 420 nM). |
|
| DCC2104 |
Fgfr4 Inhibitor 1 |
Novel, covalent, highly potent, and exquisitely specific FGFR4 inhibitor |
|
| DCC2105 |
Fgfr4 Inhibitor 5a |
Novel potent and selective covalent inhibitor of FGFR4 kinase |
|
| DCC2106 |
Fgfr4 Inhibitor 7v |
Novel highly selective covalent inhibitor of wild-type and gatekeeper mutant FGFR4, exhibiting excellent potency against FGFR4, FGFR4V550L, and FGFR4V550M with nanomolar activity in both the biochemical and cellular assays while sparing FGFR1/2/3 |
|
| DCC2107 |
Fgfr4 Inhibitor F-30 |
Novel potent and selective FGFR4 inhibitor, covalently binding to FGFR4 protein |
|
| DCC2108 |
Fgfr-in-21 |
Novel potentl and selective covalent FGFR inhibitor, inhibiting proliferation of FGFR-amplified cancer cell lines with low nM IC50 values |
|
| DCC2109 |
Fh1024 Tfa Salt |
Novel regulator of transcription factor PU.1-DNA binding interactions, acting as a weak agonist that recruits PU.1 to DNA |
|
| DCC2110 |
Fh535-n |
Novel inhibitor of the Wnt/β-catenin transcriptional activity, demonstrating significant increased rate of apoptosis in Huh7 and PLC/PRF |
|
| DCC2111 |
Fhu-779 |
Novel light-regulated diltiazem derivative, photoswitching LTCC in pancreatic β cells, cardiomyocytes and mouse hearts |
|
| DCC2112 |
Fibroblast Growth Factor (1-10) |
Fibroblast growth factor fragment |
|
| DCC2113 |
Fibronectin Adhesion-promoting Peptide |
Potent macrophage activator, enhancing interleukin 12-dependent interferon gamma production by lipopolysaccharide-stimulated mouse splenocytes, exerting an antiviral action against HSV-1 with the independent pathways of IFN-alpha |
|
| DCC2114 |
Fibronectin Cs1 Peptide |
Cell-adhesive octapeptide as the authentic sequence within intact fibronectin, mediating OSCC cell spreading, migration, and invasion, regulating IL-17A levels and mechanical allodynia after peripheral nerve injury |
|
| DCC2115 |
Finafloxacin Hydrochloride |
Antibacterial agent, expressing enhanced activity at acidic pH |
|
| DCC2116 |
Fischerin |
Natural potent cytotoxic agent |
|
| DCC2117 |
Fitc-sulfono-γ-aa Peptide |
Fluorescent protein-protein interaction (PPI) inhibitor |
|
