DCC2497 |
Hcv Gt2a Inhibitor 5m |
Antiviral agent against HCV genotype 2a JFH-1 infected in human Huh7.5.1 cells |
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DCC2498 |
Hcv-in-5 |
Novel Inhibitor of Hepatitis C Virus |
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DCC2499 |
Hd-800 |
High affinity and selective colchicine site tubuline inhibitor amenable to radiolabel with C-11, a positron emitting isotope |
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DCC2500 |
Hdac6 Degrader 14a |
Novel PROTAC HDAC6 degrader, efficiently and selectively decreased HDAC6 levels in several cell lines, including activated THP-1 cells |
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DCC2501 |
Hdac6 Degrader Np8 |
Novel potent and selective PROTAC degrader of HDAC6 protein |
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DCC2502 |
Hdac6 Inhibitor 6h |
Novel hHDAC6 inhibitor, having low inhibitory potency over hHDAC1 and hHDAC8, as potential pharmacological tools for idiopathic pulmonary fibrosis (IPF) treatment |
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DCC2503 |
Hdac6 Inhibitor Xp5 |
Novel potent HDAC6 inhibitor with an IC 50 of 31 nM and excellent HDAC6 selectivity (SI = 338 for HDAC6 over HDAC3), displaying high antiproliferative activity against various cancer cell lines including the HDACi-resistant YCC3/7 gastric cancer cells (IC |
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DCC2504 |
Hdac6-in-10c |
Novel HDAC6 isoform-selective inhibitor, increasing the acetylation level of α-tubulin with little effect on the acetylation of histone H3, inducing apoptosis in HL-60 cell by activating caspase 3 |
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DCC2505 |
Hdac6-in-3f |
Potent and selective HDAC6 inhibitor |
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DCC2506 |
Hdac6-in-4b |
Potent and selective HDAC6 inhibitor |
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DCC2507 |
Hdac6-in-w5 |
Novel highly potent and selective HDAC6 inhibitor with an IC 50 of 2.54 nM and being more than 290- to 3300-fold selective over other HDAC isoforms |
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DCC2508 |
Hdac8 Protac |
First-in-class proteolysis targeting chimera (PROTAC) for selective degradation of histone deacetylase 8 (HDAC8) |
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DCC2509 |
Hdac8-in-8b |
Novel Selective Histone Deacetylase 8 (HDAC8) Inhibitor with Anti-Neuroblastoma Activity |
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DCC2510 |
Hdac-in-6 |
Novel HDAC inhibitor, targeting HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, and HDAC9 |
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DCC2511 |
Hdac-in-h13 |
Novel Histone deacetylase (HDAC) inhibotor, displays potent inhibitory activity towards human HDACs and several cancer cells lines |
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DCC2512 |
Hdl376
Featured
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HDL376 is a scavenger receptor class B type I (SR-BI) inhibitor. HDL376 directly inhibits SR-BI-mediated lipid transport in cells and in liposomes reconstituted with purified SR-BI (IC50 = 0.22 μM). HDL376 can be used for the research of atherosclerotic coronary artery disease. |
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DCC2513 |
Hdp-mimic C4 |
Potent antifungal agent, hosting defense peptide mimic through a membrane-active mechanism |
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DCC2514 |
Hds029 |
Potent inhibitor of the ErbB receptor family (IC50 values are 0.3, 0.5 and 1.1 nM for ErbB1 (EGFR), ErbB4 and ErbB2 respectively) |
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DCC2515 |
Helenalin Acetate |
Anti-inflammatory and anti-cancer agent, disrupting the cooperation of CCAAT-box/enhancer-binding protein beta (C/EBPß) and co-activator p300 |
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DCC2516 |
Helenalin Methacrylate |
Natural anti-inflammatory and anti-cancer agent |
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DCC2517 |
Helioxanthin |
Inhibitor of interleukin-1β-induced MIP-1β production |
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DCC2518 |
Hemiasterlin |
Cytotoxic peptide, inducing mitotic arrest and abnormal spindle formation |
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DCC2519 |
Hemigossypol |
The biosynthetic precursor of gossypol |
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DCC2520 |
Hemisurfen |
Heparan sulfate antagonist |
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DCC2521 |
Heparin Disaccharide I-s Sodium Salt |
Heparin derivative for treatment of thrombotic diseases |
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DCC2522 |
Hepcidin |
Master regulator of iron homeostasis, contributing to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss |
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DCC2523 |
Hepta-histidine |
Novel inhibitor of Tau aggregation against Tau-related neurodegenerative diseases including Alzheimer's disease (AD) |
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DCC2524 |
Het-dpd-13a |
Novel LsrK inhibitor (ID 50 119 μM) agaist antimicrobial resistance (AMR) |
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DCC2525 |
Heterotaxin |
Novel TGF-β Signaling Inhibitor |
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DCC2526 |
Hetrombopag Olamine |
Novel orally bioavailable, non-peptide thrombopoietin (TPO) receptor agonist |
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