DCC2737 |
Iproclozide |
Irreversible and nonselective Monoamine_oxidase_inhibitor>monoamine oxidase inhibitor (MAOI) |
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DCC2738 |
Ips-02001 |
Novel inhibitor of protein-protein interaction (PPI), targeting integrin αvβ3-osteopontin interface, blocking OC maturation from murine bone marrow-derived macrophages, as well as the resorptive function of OCs, impairing downstream signaling of integrin |
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DCC2739 |
Ipsalazide |
Sulfasalazine analog, releasing 5-aminosalicylic acid and a nontoxic carrier molecule in the gastrointestinal tract |
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DCC2740 |
Iqs-01.01rs |
Novel potent inverse agonist of the chemokine receptor CXCR4, preventing CXCL12-mediated chemotaxis and triggering apoptosis in a panel of 18 cell lines and primary cultures, with superior mobilizing properties in vivo |
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DCC2741 |
Ir-1061 |
NIR-II cyanine dye for cancer treatment and diagnosis |
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DCC2742 |
Irak Inhibitor 3 |
Novel interleukin-1 (IL-I) receptor-associated kinase (IRAK) modulator |
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DCC2743 |
Irak3 Degrader 23 |
Novel potent and selective degrader of IRAK3, inducing proteasome-dependent degradation of IRAK3 and showing both CRBN and IRAK3 binding for activity |
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DCC2744 |
Irak4-in-13 |
Novel Orally Efficacious IRAK4 Inhibitor, Targeting MyD88L265P Mutant Diffuse Large B Cell Lymphoma |
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DCC2745 |
Irc-083864 |
Novel inhibitor of CDC25 phosphatases, actively against human cancer cells |
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DCC2746 |
ire1-in-vii |
Inhibitor of IRE1 endoribonuclease activity, strongly inhibiting XBP-1 splicing in an in vivo model of acute endoplasmic reticulum stress. |
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DCC2747 |
Irl-1620 |
ET B receptor agonist, showing anti-apoptotic activity and protecting neural cells in rats with cerebral ischemia |
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DCC2748 |
Isam-c032 |
Novel potent hA2BAR antagonist (Ki = 3.66 nM) |
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DCC2749 |
Isatin-o |
Neutral BBB crossing reactivator for acetylcholinesterase inhibited by paraoxon, also acting as anticonvulsant |
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DCC2750 |
Isbogrel |
Selective thromboxane A2 (TXA2) synthase inhibitor |
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DCC2751 |
Isir-005 |
Natural Stabilizer of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface |
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DCC2752 |
Iso-dehydrozingerone |
Novel osteoclastogenesis inhibitor, preventing ovariectomy-induced osteoporosis in ddY mice |
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DCC2753 |
Isofagomine |
Iminosugar, binding selectively to N370S glucocerebrosidase and restoring its correct conformation and, consequently, enhancing its activity |
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DCC2754 |
Isomazole |
Potent inotropic agent, inhibiting both PDE3 and PDE4 |
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DCC2755 |
Isomyristicin |
Natural essential oil, showing activity against T. muris |
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DCC2756 |
Isopedopeptin B |
Natural antibacterial agent with cytotoxicity and hemolytic properties against a larger panel of Gram-negative bacteria |
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DCC2757 |
Iso-ppads |
P2X-purinoceptor antagonist |
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DCC2758 |
Isowighteone |
Natural genistein derivetive with antibacterial and antifungal activities |
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DCC2759 |
Isoxaben |
Inhibitor of the cellulose biosynthesis, inhibiting anisotropic cell expansion resulting in a severely swollen and stunted growth phenotype |
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DCC2760 |
Isox-inact |
Biological Active Reagents |
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DCC2761 |
Isph Inhibitor 23.20-tpp |
Novel prodrug of potent IspH inhibitor, killing clinical isolates of several multidrug-resistant bacteria, including those from the genera Acinetobacter, Pseudomonas, Klebsiella, Enterobacter, Vibrio, Shigella, Salmonella, Yersinia, Mycobacterium and Baci |
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DCC2762 |
Isp-vt |
Novel inhibitor of COX and neutrophil migration |
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DCC2763 |
Isq-1 Hydrochloride |
Distinct IKur blocker |
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DCC2764 |
Ist-622 |
Unique topoisomerase inhibitor, showing significant growth-inhibitory effects against large-cell lung cancer (Lu-116) and gastric adenocarcinoma (St-4) |
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DCC2765 |
Isvy130 |
Novel Potent and Selective A3 Antagonist |
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DCC2766 |
Ite-atra |
Novel degrader of CRABP proteins |
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