| DC24132 |
Haloxon |
An organophosphorus anthelmintic used against nematodes of the abomasum and small intestine in ruminants. . |
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| DC24008 |
Eperezolid
Featured
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An oxazolidinone antibiotic that possesses potent antimicrobial activity in vitro and in vivo.. |
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| DC20418 |
InS3-54
Featured
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An STAT3 inhibitor that selectively targets the DNA-binding domain of STAT3, without affecting the activation and dimerization of STAT3. |
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| DC22570 |
eN-IN-1 |
An α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN. |
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| DC20307 |
AN-12-H5 |
AN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM. |
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| DC12168 |
AN2718 |
AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism. |
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| DC7804 |
Anacetrapib(MK0859)
Featured
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Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3. |
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| DC9429 |
Anagliptin |
Anagliptin is a potent and selective DPP-4 inhibitor(IC50= 3.8 nM); > 10 fold less potent for DPP-8 and DPP-9.
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| DC9580 |
Anagrelide (hydrochloride) |
Anagrelide Hydrochloride(BL4162A) is a drug used for the treatment of essential thrombocytosis.
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| DCAPI1425 |
Anastrozole
Featured
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Anastrozole is known to inhibit the CYP19 enzyme (aromatase, IC50 = 15 nM) that converts androgens to estrogens. Anastrozole has been seen to reversibly bind to the CYP19 enzyme through competitive inhibition. |
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| DC20085 |
Androgen receptor modulators 1 |
Androgen receptor modulators 1 is a selective androgen receptor modulator (SARM). Androgen receptor modulators 1 has strong agonistic activities with an EC50 of 4.7 nM. |
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| DC12143 |
Anemarrhenasaponin I |
Anemarrhenasaponin I, a traditional Chinese medicine, is isolated from Anemarrhena asphodeloides Bunge. |
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| DC12113 |
Anemarsaponin E |
Anemarsaponin E is extracted from Anemarrhena asphodeloides Bunge and has anti-inflammatory activity. |
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| DC24123 |
Angiotensin 1-7 |
Angiotensin (1-7) (Ang-(1-7)) is an active heptapeptide of the Renin-angiotensin system (RAS), inhibits purified canine angiotensin converting enzyme (ACE) activity with IC50 of 0.65 uM. |
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| DC9348 |
Angiotensin II human |
Angiotensin II human is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure.
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| DC24109 |
Anguizole |
Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM. |
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| DCAPI1490 |
Anidulafungin
Featured
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Anidulafungin |
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| DC20670 |
ANT431
Featured
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ANT431 is a novel potent metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2, shows a comparatively weak inhibitor of VIM-1 and IMP-1 (Ki of 14.6 and 4.15 uM, respectively). |
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| DC20671 |
ANT431 sodium |
ANT431 sodium is a novel, highly water-soluble metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2, shows a comparatively weak inhibitor of VIM-1 and IMP-1 (Ki of 14.6 and 4.15 uM, respectively). |
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| DC23276 |
Antimalarial compound 49c |
Antimalarial compound 49c is a potent antimalarial peptidomimetic inhibitor originally developed against Plasmepsin II selectively targets TgASP3, PfPMIX, and PfPMX, shows very potent antimalarial effects only after 72 h of treatment with IC50 of 0.6 nM. |
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| DC20308 |
Antimycin A |
Antimycin A is an inhibitor of cellular respiration, specifically oxidative phosphorylation, binds to the Qi site of cytochrome c reductase, disrupts the Q-cycle of enzyme turn over. |
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| DC8959 |
Antipyrine |
Antipyrine is an analgesic and antipyretic agent |
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| DC22094 |
ANY1 |
ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA). |
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| DC20078 |
AP1867
Featured
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AP1867 is a synthetic FKBP12F36V-directed ligand. |
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| DC22207 |
AP1903
Featured
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AP1903 (Rimiducid, AP-1903) is a potent, specific synthetic ligand of FKBP Phe36Val mutant (F36V-FKBP) with binding IC50 of 1.8 nM. |
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| DC8581 |
AP219 |
AP219 is a control compound for AP39, containing the triphenylphosphonium scaffold but lacking the H2S-releasing portion. |
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| DC5198 |
ALK-IN-1 (Brigatinib analog)
Featured
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ALK-IN-1 (Brigatinib analog) is a potent and selective active inhibitor of anaplastic lymphoma kinase(ALK), Patent US20140066406 A1. |
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| DC12705 |
APA modulator T4 |
APA modulator T4 is a small modulator of alternative polyadenylation (APA) with IC50 of 2.1 uM in reporter assays, modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts. |
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| DC12706 |
APA modulator T5 |
APA modulator T5 is a small modulator of alternative polyadenylation (APA), modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts. |
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| DC12636 |
Apararenone
Featured
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Apararenone (MT-3995) is a novel potent, selective non-steroidal mineralocorticoid receptor antagonist for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.. |
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