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| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC22549 | KDM5A-IN-1 | An inhibitor of histone demethylase.. |
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| DC23937 | SIBA | An inhibitor of the IMP-selective cytosolic 5'-nucleotidase (IC50=2-6 mM). |
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| DC22360 | Valifenalate | An insecticide agent that is approved for application on high-value crops such as grapes, tomatoes and other vegetables.. |
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| DC24195 | Benoxafos | An insecticide agent.. |
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| DC24177 | Mitiglinide calcium hydrate Featured | An insulin secretion stimulator by closing the ATP-sensitive potassium KATP channels in pancreatic β cells. |
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| DC24164 | Proparacaine hydrochloride | An irreversible local anesthetic. |
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| DC22612 | Afatinib Featured | An irreversible, dual EGFR/HER2 inhibitor with IC50 of 0.5/0.4/10/14 nM for wt EGFR/EGFR L858R/EGFR L858R+T790M/HER2 respectively. |
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| DC11640 | PK-11195 Featured | PK 11195 is a ligand of translocator protein. It targets Leishmania chemotherapy (IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively). |
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| DC22576 | MSI-1436 | An non-competitive, allosteric inhibitor of PTP1B with Ki of 0.6 uM for PTP1B1-405. |
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| DC11911 | Rovazolac Featured | Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1. |
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| DC22997 | BI-653048 | An oral glucocorticoid agonist for the treatment of rheumatoid arthritis.. |
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| DC24069 | CI-947 Featured | An orally active adenosine receptor agonist that can induce acute cardiovascular toxicity and coronary vascular injury in vivo.. |
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| DC23721 | Metribolone | An orally active anabolic-androgenic steroid and a 19-nortestosterone derivative that has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.. |
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| DC11934 | LQB-118 | An orally active pterocarpanquinone that exhibits antitumoral and antileishmanial activity both in vitro and in vivo. |
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| DC24141 | Lexibulin dihydrochloride | An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. |
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| DC23019 | PACMA 31 Featured | An orally active, irreversible inhibitor of protein disulfide isomerase (PDI), forming a covalent bond with the active site cysteines of PDI. |
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| DC22713 | L-733060 | An orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM. |
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| DC22690 | L-733060 hydrochloride | An orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM. |
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| DC21705 | STX-213 | An orally active, second-generation steroid sulfatase inhibitor with IC50 of 0.5 nM. |
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| DC22943 | Laniquidar | An orally active, third-generation P-glycoprotein inhibitor that inhibits the drug efflux pump P-glycoprotein, resulting in higher concentrations of antineoplastic agents in tumor cells that are multi-drug resistant due to the overexpression of P-glycopro |
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| DC22793 | PF 04942847 | An orally available, ATP-competitive, small-molecule inhibitor of HSP90 with Ki of 6 nM. |
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| DC21242 | LM11A-31 dihydrochloride Featured | An orally available, brain penetrant p75NTR ligand that blocks p75-mediated cell death, also increases proliferation and survival of hippocampal neural progenitors. |
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| DC20609 | Elobixibat | An orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor for the treatment of constipation.. |
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| DC23854 | Vorolanib | An orally available, small molecule dual VEGFR/PDGFR kinase inhibitor with antiangiogenic and antineoplastic activities. |
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| DC23240 | Athidathion | An organophosphate insecticide agent.. |
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| DC24132 | Haloxon | An organophosphorus anthelmintic used against nematodes of the abomasum and small intestine in ruminants. . |
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| DC24008 | Eperezolid Featured | An oxazolidinone antibiotic that possesses potent antimicrobial activity in vitro and in vivo.. |
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| DC20418 | InS3-54 Featured | An STAT3 inhibitor that selectively targets the DNA-binding domain of STAT3, without affecting the activation and dimerization of STAT3. |
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| DC22570 | eN-IN-1 | An α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN. |
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| DC20307 | AN-12-H5 | AN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM. |
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