| DC22544 |
AR-C155858 |
AR-C155858 is a potent monocarboxylate transporter MCT1 and MCT2 with Ki of 2.3 nM and <10 nM, displays no activity at MCT4. |
|
| DC20265 |
Arctigenin
Featured
|
Arctigenin is an extract from A. lappa, a burdock plant traditionally used in Japanese Kampo medicine for its antioxidant, anti-inflammatory, |
|
| DC9659 |
Arctiin(NSC 315527)
Featured
|
Arctiin, a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis. |
|
| DC12359 |
Arg-AMS |
Arg-AMS is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes. |
|
| DCAPI1329 |
Argatroban
Featured
|
Argatroban |
|
| DC8841 |
Argatroban monohydrate
Featured
|
Argatroban monohydrate is a direct, selective thrombin inhibitor. |
|
| DC9645 |
(+)-Arglabin
Featured
|
Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella; anticancer natural compound. |
|
| DC23605 |
AR-HO47108 |
AR-HO47108 is a potent, selective acid pump antagonist (potassium-competitive acid blocker or P-CAB) that reversiblely inhibits gastric H+/K+-ATPase with pIC50 of 7.0. |
|
| DC10110 |
ARM390 Hydrochloride
Featured
|
ARM390 is a non-peptidic, low-internalizing δ-selective opioid receptor agonist. |
|
| DC20677 |
ARN 077 |
ARN077 is the first potent, selective N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 7 nM on both rat NAAA and human NAAA. |
|
| DC12569 |
ARN14494 |
ARN14494 (ARN-14494) is a potent, small molecule serine palmitoyltransferase (SPT) inhibitor with IC50 of 27.3 nM. |
|
| DC22000 |
ARN19874 |
ARN19874 (ARN-19874) is the first selective, cell-active inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) with IC50 of 33.7 uM. |
|
| DC9345 |
ARN2966(2-PMAP)
Featured
|
ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ. |
|
| DC20676 |
ARN-3261 |
ARN-3261 is a potent, selective, orally available salt inducible kinase SIK2 and SIK3 inhibitor with IC50 of 11 nM and 19 nM, respectively. |
|
| DC20678 |
ARN 726 |
ARN726 is a potent, selective, orally bioavailable N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 63 nM (r-NAAA) and 27 nM (h-NAAA). |
|
| DC12460 |
ARP101 |
ARP101 (ARP-101) is a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells. |
|
| DC7820 |
ARQ 621
Featured
|
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1. |
|
| DC20679 |
ARRY-502 |
ARRY-502 is an orally bioavailable, potent and selective antagonist of the prostaglandin D2 receptor (CRTh2) for treatment of mild to moderate Th2-driven asthma.. |
|
| DC8181 |
Filanesib(ARRY-520)
Featured
|
ARRY-520 is a synthetic, small molecule kinesin spindle protein (KSP) inhibitor with IC50 of 6 nM. |
|
| DC9495 |
ARRY-520 (R enantiomer) |
ARRY-520 R enantiomer is the R form of ARRY-520, which is a synthetic, small molecule kinesin spindle protein (KSP) inhibitor with IC50 of 6 nM.
|
|
| DC21452 |
Artefenomel |
Artefenomel (OZ439) is a novel, next-generation antimalarial ozonide that demonstrates high potentcy against P. falciparum in vitro and P. berghei in vivo (K1/NF54, IC50=2.0/3.2 nM).. |
|
| DC21451 |
Arterolane |
Arterolane (OZ277. |
|
| DCAPI1125 |
Articaine HCl |
Articaine is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue. |
|
| DC12614 |
Arylsulfonamide 64B |
Arylsulfonamide 64B (HIF inhibitor 64B) is a small molecule HIF pathway inhibitor, blocks hypoxia-induced expression of c-Met and CXCR4 and uveal melanoma (UM) cell migration. |
|
| DC20687 |
AS 2553627 |
AS 2553627 (AS2553627) is a novel potent, selective pan-JAK inhibitor with IC50 of 0.46, 0.30, 0.14 and 2.0 nM for JAK1, JAK2, JAK3 and TYK2, respectively. |
|
| DC22001 |
AS-1269574
Featured
|
AS-1269574 is a selective, orally available GPR119 agonist with EC50 of 2.5 uM in cell-based cAMP assays. |
|
| DC22002 |
AS1928370 |
AS1928370 (ASP8370) is a potent, selective, orally available TRPV1 antagonist with IC50 of 0.51 uM, shows no inhibitory effects on TRPV4, TRPA11, and TRPM8 at 10 uM. |
|
| DC22766 |
AS-1949490 |
AS-1949490 (AS1949490) is a potent, selective SHIP2 inhibitor with IC50 of 0.34/0.62 uM for mouse/human SHIP2. |
|
| DC20682 |
AS2521780 |
AS2521780 is a potent, selective, orally bioavailable PKCθ inhibitor that inhibits combinant human PKCθ enzyme with IC50 of 0.48 nM, >30-fold higher than other PKC isoforms. |
|
| DC3112 |
AS-252424
Featured
|
AS-252424 is a novel, potent and selective inhibitor of PI3Kγ with IC50 of 33 nM. |
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