| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC23111 | Ampkinone | Ampkinone is a novel small molecule activator of AMPK, stimulates the phosphorylation of AMPK via indirect activation of AMPK in various cell lines (2.7-fold at 10 uM). |
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| DC11274 | AMPPD Featured | AMPPD, 1,2-dioxo-cyclohexane derivatives, is a new biochemistry ultrasensitive alkaline phosphatase substrate. |
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| DC11076 | Ampreloxetine | Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively. |
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| DC7058 | Amprenavir Featured | Amprenavir (Agenerase) is a HIV protease inhibitor(Ki=0.6 nM) used to treat HIV infection. |
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| DC23625 | AMR-2 | AMR-2 is a highly potent, orally active, triple reuptake inhibitor of SERT, NET, and DAT with IC50 of 3.0, 3.1, and 8.3 nM, respectively. |
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| DC7002 | Amrubicin(SM-5887) | Amrubicin(SM-5887) is a novel anthracycline derivative for treatment of bladder carcinoma. |
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| DC9634 | Amsacrine | Amsacrine (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells. |
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| DC7510 | TAC-101 | amsilarotene (TAC-101) is a retinobenzoic acid with potential antineoplastic activity. TAC-101 inhibits retinoblastoma-gene product (RB) phosphorylation and increases the presence of 2 cyclin-dependent kinase (CDK) inhibitors, resulting in cell cycle arrest. This agent also causes a cytotoxic decline in cyclin A and thymidylate synthase expression. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).For the detailed information of TAC-101, the solubility of TAC-101 in water, the solubility of TAC-101 in DMSO, the solubility of TAC-101 in PBS buffer, the animal experiment (test) of TAC-101, the cell expriment (test) of TAC-101, the in vivo, in vitro and clinical trial test of TAC-101, the EC50, IC50,and Affinity of TAC-101, Please contact DC Chemicals.. |
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| DC7324 | Amuvatinib (MP-470) Featured | Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. |
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| DC20088 | Amuvatinib hydrochloride (MP470 hydrochloride; HPK 56 hydrochloride) | Amuvatinib hydrochloride (MP470 hydrochloride) is a multi-targeted receptor tyrosine kinases inhibitor, which inhibits c-Kit (D816V), c-Kit (D816H), c-Kit (V560G), c-Kit (V654A), PDGFRα (D842V), and PDGFRα (V561D) with IC50s of 950 nM, 10 nM, 34 nM, 127 n |
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| DC21995 | AMXT-1501 | AMXT-1501 (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination of with DFMO. |
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| DC21996 | AMXT-1501 tetrahydrochloride | AMXT-1501 tetrahydrochloride (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination with DFMO. |
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| DC23109 | AMZ30 | AMZ30 is a potent, selective, covalent inhibitor of the serine hydrolase protein phosphatase methylesterase-1 (PME-1) with IC50 of 0.6 uM, >100-fold selectivity over other SHs. |
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| DC25088 | Rivastigmine Featured | An acetylcholinesterase (AChE) inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. |
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| DC11651 | HLY-78 Featured | HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction[1]. |
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| DC22762 | Norendoxifen | An active metabolite of the selective estrogen receptor modulator (SERM) tamoxifen. |
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| DC23227 | N6-Cyclohexyladenosine Featured | An adenosine A1 receptor agonist (EC50= 8.2 nM).. |
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| DC24153 | Cysteamine hydrochloride | An agent for the treatment of nephropathic cystinosis and an antioxidant. |
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| DC23931 | Hydrastine | An alkaloid of Hydrastis canadensis used in many dietary supplements intended to enhance the immune system. |
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| DC11657 | PPT(Propyl pyrazole triol ) Featured | Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%). |
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| DC21630 | SCF-I2 | An allosteric, sepecific inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase with IC50 of 6.2 uM in FP assyas. |
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| DC22888 | β2AR-IN-15 | An allosteric, small-molecule negative modulator for β2AR with Kd of 1.7 uM. |
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| DC22827 | DBCO-NHS ester | An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine. |
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| DC21155 | Myriocin | An amino fatty acid antibiotic that is 10- to 100-fold more potent than cyclosporin A as an immunosuppressive agent of the immune response in vitro and in vivo. |
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| DC24145 | G-418 disulfate Featured | An aminoglycoside antibiotic similar in structure to gentamicin B1. |
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| DC24005 | Apramycin | An aminoglycoside antibiotic used in veterinary medicine.. |
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| DC22371 | Rocuronium | An aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia. . |
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| DC22575 | MLN-4924 hydrochloride | An analog of adenosine 5’-monophosphate that potently and selectively inhibits NEDD8-activating enzyme (NAE) with IC50 of 4.7 nM. |
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| DC20908 | Beloranib hemioxalate | An analog of the natural compound Fumagillin that functions as a highly potent methionine aminopeptidase 2 (MetAP2) inhibitor. |
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| DC24054 | Poloxime Featured | An analog of thymoquinone that blocks pSer/pThr recognition by Plk1 Polo-box domain as a phosphate mimic.. |
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