| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC7001 | AMG-47a Featured | AMG-47a is a potent inhibitor of Lck and T cell proliferation; exhibits anti-inflammatory activity (ED50 = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice. |
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| DC20664 | AMG-548 Featured | AMG-548 is a potent and selective inhibitor of p38α with Ki of 0.5 nM, dispalys weak inhibition for p38β (Ki=3.6 nM), and >5,000-fold selectivity over p38γ and p38δ; shows >1,000-fold selectivity over other 36 kinases, and is efficacious in acute and chro |
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| DC11878 | AMG-579 | AMG-579 is a potent, selective, CNS penetrant, orally bioavailable PDE10A inhibitor with IC50 of 0.1 nM. |
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| DC12430 | AMG7703 | AMG7703 (4-CMTB, AMG-7703) is an allosteric, selective agonist of FFAR2 (GPR43).. |
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| DC10132 | AMG9810 Featured | AMG9810 is a potent and selective, competitive vanilloid TRPV1 receptor antagonist (IC50 = 17 nM). |
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| DC11180 | Amgen 16 | Amgen16 is a highly potent inhibitor of NF-κB inducing Kinase (NIK), example 294 in patent WO 2009158011 A1.. |
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| DC8503 | AMG-Tie2-1 Featured | AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC50 <1 nM). |
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| DC8292 | AMI-1 Featured | AMI-1 is a PRMT and HIV-1 RT polymerase inhibitor. |
|
| DC9548 | Amicarbazone | Amicarbazone(BAY-MKH3586; BAY314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); herbicide with a broad spectrum of weed control. |
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| DCAPI1263 | Amidopyrine | Amidopyrine is white crystalline substance used as an analgesic and antipyretic. |
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| DCAPI1043 | Amikacin hydrate | Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. |
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| DCAPI1279 | Aminocaproic acid (Amicar) | Aminocaproic acid (Amicar)is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders. |
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| DC8984 | Aminoglutethimide | Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM. |
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| DC11324 | Aminopeptidase N Inhibitor | Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). |
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| DC11193 | Aminopyridine 2 | Aminopyridine 2 (MPO inhibitor AP-2) is a novel potent, selective, orally available inhibitor of Myeloperoxidase (MPO), inhibits MPO peroxidase activity in vitro and in human plasma with IC50 of 0.16 and 1.9 uM, respectively. |
|
| DC9189 | Amiodarone HCl | Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM. |
|
| DC20206 | Amitriptyline；MK-230, N-750, Ro41575 | Amitriptyline is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. |
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| DC9181 | Amlodipine Besylate | Amlodipine besylate is a long-acting calcium channel blocker. |
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| DCAPI1067 | Ammonium Glycyrrhizinate (AMGZ) | Ammonium Glycyrrhizinate (AMGZ) |
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| DC20178 | Pyrrolidinedithiocarbamate ammonium;APDC, PDTC Featured | Ammonium pyrrolidine dithiocarbamate (PDTC) is a potent nuclear factor-κB (NF-κB) inhibitor that inhibits IκB phosphorylation, blocks NF-κB translocation to the nucleus and reduces the expression of downstream cytokines. |
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| DC20188 | Amodiaquine | Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria. |
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| DC8923 | AS-1413(Amonafide) | Amonafide(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage. |
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| DCAPI1343 | Amorolfine HCl Featured | Amorolfine hydrochloride is a antifungal reagent. |
|
| DC10698 | Amoscanate Featured | Amoscanate(nithiocyamine) is an experimental anthelmintic agent of the arylisothiocyanate class which was found to be highly effective in animals against the four major species of schistosomes which infect humans,and is also highly active against hookworm |
|
| DCAPI1158 | Amoxicillin sodium (Amox) | Amoxicillin sodium (Amox) |
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| DC5075 | BDP-12(Ampalex) Featured | Ampalex (Ampakine CX516) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). |
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| DCAPI1309 | Ampicillin sodium | Ampicillin is a beta-lactam antibiotic that is part of the aminopenicillin family. |
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| DC9406 | Ampiroxicam | Ampiroxicam(CP65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug. |
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| DC11130 | AMPK activator 991 | AMPK activator 991 is an allosteric AMPK activator, activates non-phosphorylated Thr172 AMPK in vitro binds to α1β1γ1 and α2β1γ1 with Kd of 0.13 and 0.17 uM, respectively.. |
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| DC11129 | AMPK activator SC4 | AMPK activator SC4 is a potent, specific activator of α2β2-AMPK complexes with EC50 of 17.2 and 82.1 nM for α2β2γ1 and α2β2γ3, the predominant AMPK isoform complexes in human skeletal muscle. |
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