| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC20352 | CYP11B1-IN-25 | CYP11B1-IN-25 is a selective, potent 11β-hydroxylase (CYP11B1) inhibitor with IC50 of 2 nM, displays 14-fold selectivity over CYP11B2. |
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| DCAPI1536 | Cyproheptadine Hydrochloride | Cyproheptadine hydrochloride is a migraine prophylactic and Non-selective SR-2A (5HT2) antagonist. Cyproheptadine hydrochloride is an inhibitor of Histamine H1 Receptor and SR-2C. |
|
| DC3107 | Momelotinib (CYT387,CYT-387) Featured | CYT387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50 of 11 nM and 18 nM, respectively. |
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| DC5134 | lexibulin (CYT997) | CYT997 is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines. Phase 1/2. |
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| DCAPI1295 | Cytidine | Cytidine |
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| DC9835 | Cytochalasin H Featured | Cytochalasin H is a potent inhibitor of actin incorporation into filaments,a cell-permeable fungal toxin used in actin polymerization studies and cytological research. |
|
| DCAPI1566 | Cytarabine hydrochloride Featured | Cytosine β-D-arabinofuranoside hydrochloride is an anti-leukemic agent which binds to topoisomerase I resulting in DNA fragmentation and inhibition of replication. In addition this compound does not have any effects on RNA synthesis. Cytosine β-D-arabinof |
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| DC10125 | CZ415 Featured | CZ415 is a potent and highly selective mTOR inhibitor. |
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| DC7734 | CZC24832 Featured | CZC24832 is the first selective PI3Kγinhibitor with IC50 of 27 nM, with 10-fold selectivity over PI3Kβ and >100-fold selectivity over PI3Kα and PI3Kδ. |
|
| DC7113 | CZC-25146 Featured | CZC-25146 is a potent, selective and metabolically stable LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2 respectively. |
|
| DC8082 | CZC-54252 Featured | CZC-54252 is a potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) (IC50 values are 1.28 nM and 1.85 nM for wild-type and G2019S mutant forms of LRRK2 respectively). |
|
| DC11199 | CZh226 Featured | CZh226 hydrochloride (CZh-226) is a potent, selective inhibitor of p21-activated kinase 4 (PAK4) with Ki of 9 nM, displays 346-fold selectivity over PAK-1. |
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| DC11198 | CZh226 hydrochloride | CZh226 hydrochloride (CZh-226) is a potent, selective inhibitor of p21-activated kinase 4 (PAK4) with Ki of 9 nM, displays 346-fold selectivity over PAK-1. |
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| DC9886 | D-(+)-Cellobiose | D-(+)-Cellobiose is a substrate of β-glucosidase. |
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| DC12296 | D-(+)-Trehalose dihydrate | D-(+)-Trehalose dihydrate can be used as a food ingredient and pharmaceutical excipient. |
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| DC12252 | D,L-Buthionine-(S,R)-sulfoximine Featured | D,L-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis. |
|
| DC12582 | D13-9001 | D13-9001 (D 13-9001) is a small molecule, MexAB-OprM specific efflux pump inhibitor with good potency in vitro (MPC 2 ug/mL) and displays excellent activity in vivo in a rat pneumonia model of P. aeruginosa.. |
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| DC25001 | D-156844 | D156844 is a potent SMN2 inducer and DcpS inhibitor. |
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| DC12610 | D159153 | D159153 (D-159153) is a novel potent, allosteric inhibitor of PDE4 with cellular IC50 of 28.5 and 6.6 nM for PDE4B1 and PDE4D3, respectively.. |
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| DC20219 | D159687 Featured | D159687 is a selective negative allosteric modulator (NAM) of PDE4D. |
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| DC9850 | D-3263 HCl Featured | D3263 is a novel, orally bioavailable small molecule Trp-p8 agonist. |
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| DC7011 | D4476 (D-4476) Featured | D4476, a cell-permeant inhibitor of CK1δ (IC90 <10 uM), suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a, D4476 originally identified as inhibitors of activin receptor-like kinase ALK5. |
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| DC11124 | D-520 | D-520 is a potent, multifunctional D2/D3 agonist with Ki of 41.8 /0.35 nM, modulates aggregation of alpha-synuclein (αSN) and reduces toxicity of preformed aggregates of αSN. |
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| DC20053 | D5D-IN-326 | D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and d |
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| DC9589 | D609 Featured | D609 is a selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (Ki = 6.4 μM); antiviral and antitumor agent. |
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| DC7393 | D-64131 Featured | D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to αβ-Tubulin. |
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| DC11232 | D715-2441 | D715-2441 (D 715-2441) is a novel antiviral compound that interferes with the conserved cap-binding domain of the PB2 protein, exhibits potent antiviral activity against influenza A viruses (IAVs) with IC50 of 1.7-4.4 uM. |
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| DC9259 | DAA1106 Featured | DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptors, in mitochondrial fractions of the rat brain. |
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| DC8913 | Dabigatran etexilate mesylate Featured | Dabigatran etexilate mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. |
|
| DC5149 | Dabrafenib Featured | Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. Phase 3. |
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